Results 21 to 30 of about 396,196 (289)

Ekspresi dan Aktivasi Sub Unit p65 NF-κB pada Sel Mononuklear Penderita Sindrom Nefrotik Resisten Steroid Anak

Jurnal Kedokteran Brawijaya, 2013
Resitance  to  steroid  therapy  is  a  poor  prognosis  sign  for  nephrotic  syndrome,  but  this  mechanism is  still unclear. NF-κB has been reported to affect the glucocorticoid at the T cell through the transrepression in  the glucocorticoid  receptor .  Until  know,  this  study  was  still  limited.  The  aim  of  
Brigitta Ida RV Corebima, Krisni Subandiyah, Loeki Enggar Fitri   +2 more
openaire   +2 more sources

WITHDRAWN: Inhibition of CHOP weakens the promotion of chronic intermittent hypoxia on epithelial cells apoptosis via inhibiting PI3K-Akt and NF-κB signaling pathways

Oncotarget, 2017
// Yi-Bin Wang 1, * , Yin Ni 2, * , Ren-Hua Sun 2 , Xiao-Zhou Mou 3 , Fang Han 2 , Qian Li 2 , Hai-Jun Huang 4 , Jing-Quan Liu 2 and Yue-Xing Tu 2 1 Department of Cardiology, Chun’an First People’s Hospital, Zhejiang Provincial People’s Hospital Chun’an Branch, Hangzhou, Zhejiang 311700, China 2 Department of Critical Care Medicine ...
Yi-Bin Wang, Yi-Bin Wang, Yin Ni, Yin Ni, Ren-Hua Sun, Ren-Hua Sun, Xiao-Zhou Mou, Xiao-Zhou Mou, Fang Han, Fang Han, Qian Li, Qian Li, Hai-Jun Huang, Hai-Jun Huang, Jing-Quan Liu, Jing-Quan Liu, Yue-Xing Tu, Yue-Xing Tu   +17 more
openaire   +1 more source

Ginkgetin inhibits proliferation of HeLa cells via activation of p38/NF-κB pathway

Cellular and Molecular Biology, 2019
Effect of ginkgetin on proliferation of human cervical cancer (HeLa) cells and the underlying mechanism   were investigated. Human cervical cancer (HeLa) cells were cultured at 37 °C in 10 % fetal bovine serum (FBS) supplemented RPMI 1640 medium in a humidified incubator containing 5 % CO2.
Jianxia, Cheng, Yun, Li, Jianping, Kong
openaire   +3 more sources

Dexamethasone suppresses interleukin-1β-induced human β-defensin 2 mRNA expression: involvement of p38 MAPK, JNK, MKP-1, and NF-κB transcriptional factor in A549 cells [PDF]

FEMS Immunology & Medical Microbiology, 2007
Human beta-defensin (HBD)-2 is an inducible antimicrobial peptide that plays an important role in innate immunity. Glucocorticoids, on the other hand, exert immunosuppressive and anti-inflammatory actions. We have previously reported that interleukin (IL)-1beta induces HBD-2 mRNA expression through the activation of nuclear factor-kappaB (NF-kappaB ...
Byeong-Churl Jang, Ki-Jo Lim, Min-Ho Suh, Jong-Gu Park, Seong-Il Suh   +4 more
openaire   +3 more sources

Nuclear Factor-κB/p65 (Rel A) Is Constitutively Activated in Human Prostate Adenocarcinoma and Correlates with Disease Progression

Neoplasia: An International Journal for Oncology Research, 2004
Aberrant nuclear factor-κB (NF-κB) activation has been implicated in the pathogenesis of several human malignancies. In this study, we determined whether NF-κB is constitutively activated in human prostate adenocarcinoma, and, if so, whether increased NF-
Sanjeev Shukla, Gregory T. MacLennan, Pingfu Fu, Jigar Patel, Susan R. Marengo, Martin l. Resnick, Sanjay Gupta   +6 more
doaj   +1 more source

The Role of Ubiquitination in NF-κB Signaling during Virus Infection

Viruses, 2021
The nuclear factor κB (NF-κB) family are the master transcription factors that control cell proliferation, apoptosis, the expression of interferons and proinflammatory factors, and viral infection. During viral infection, host innate immune system senses
Kun Song, Shitao Li
doaj   +1 more source

Fatty Acid Metabolism Provides an Essential Survival Signal in OxPhos and BCR DLBCL Cells

Biomedicines
Backgroung/objectives: Diffuse large B-cell lymphoma (DLBCL) is the most frequent subtype of malignant lymphoma and is a heterogeneous disease with various gene and chromosomal abnormalities.
Aurélie Montagne, Konstantina Kotta, Karoline Kielbassa-Elkadi, Isabelle Martins, José Ángel Martinez-Climent, Guido Kroemer, Catherine Thieblemont, Véronique Baud   +7 more
doaj   +1 more source

Kombinasi Artemisinin dan Ekstrak Moringa oleifera Menurunkan Ekspresi NF-κB namun Tidak Menurunkan Ekspresi iNOS pada Otak Mencit Diinfeksi Malaria

Jurnal Kedokteran Brawijaya, 2015
Malaria otak merupakan manifestasi tersering dari infeksi malaria berat yang ditandai dengan respon inflamasi berlebih di otak. Untuk mencegah terjadinya resistensi, penggunaan obat antimalaria standar (artemisinin) harus dikombinasikan dengan obat antimalaria lain.
Herpan Syafii Harahap, Mochammad Dalhar, Tinny Endang Endang H, Eviana Norahmawati, Loeki Enggar Fitri   +4 more
openaire   +2 more sources

Plant polyphenols as inhibitors of NF-κB induced cytokine production—a potential anti-inflammatory treatment for Alzheimer's disease? [PDF]

Frontiers in Molecular Neuroscience, 2015
Alzheimer’s disease (AD) is a neurodegenerative disorder that impacts the daily lives of many sufferers throughmemory loss as well as behavioral and cognitive changes. AD is themost common form of dementia. One in ten people over the age of 65, and around half of those over 85 have AD.
Karunaweera, Niloo (S31677), Raju, Ritesh (R17740), Gyengesi, Erika (R17270), Muench, Gerald (R12224)   +3 more
openaire   +3 more sources

The Ubiquitination of NF-κB Subunits in the Control of Transcription

Cells, 2016
Nuclear factor (NF)-κB has evolved as a latent, inducible family of transcription factors fundamental in the control of the inflammatory response. The transcription of hundreds of genes involved in inflammation and immune homeostasis require NF-κB ...
Patricia E. Collins, Izaskun Mitxitorena, Ruaidhrí J. Carmody   +2 more
doaj   +1 more source