Results 11 to 20 of about 456,853 (317)

TLR4-MyD88-NF-κB signaling pathway contributes to the progression of secondary hepatic injury and fibrosis in hepatolithiasis

European Journal of Inflammation, 2021
This paper focused on evaluating the effect of TLR4-MyD88-NF-κB signaling pathway in the progression of secondary hepatic injury and fibrosis in hepatolithiasis.
Yuan Fang, Lulu Zhou, Xiaoxuan Hu, Jingyun Guo, Jinmao Liao, Zheng Zhang   +5 more
doaj   +1 more source

Research progress on the effect of traditional Chinese medicine on the activation of PRRs-mediated NF-κB signaling pathway to inhibit influenza pneumonia

Frontiers in Pharmacology, 2023
Influenza pneumonia has challenged public health and social development. One of the hallmarks of severe influenza pneumonia is overproduction of pro-inflammatory cytokines and chemokines, which result from the continuous activation of intracellular ...
Ling Zhang, Xiong Ye, Yuntao Liu, Zhongde Zhang, Xueshan Xia, Shuwei Dong   +5 more
doaj   +1 more source

BYHWD Alleviates Inflammatory Response by NIK-Mediated Repression of the Noncanonical NF-κB Pathway During ICH Recovery

Frontiers in Pharmacology, 2021
Intracerebral hemorrhage (ICH) is a life-threatening type of stroke that lacks effective treatments. The inflammatory response following ICH is a vital response that affects brain repair and organism recovery.
Wei Xiao, Zehui He, Weikang Luo, Dandan Feng, Yang Wang, Tao Tang, Ali Yang, Jiekun Luo   +7 more
doaj   +1 more source

The Expression of NF-kB Signaling Pathway Was Inhibited by Silencing TGF-b4 in Chicken IECs Infected with E. tenella [PDF]

Brazilian Journal of Poultry Science, 2020
Chicken coccidiosis is a parasitic disease caused by one or more species of Eimeria infection with severe consequences. The NF-κB signaling pathway and TGF-β4 play an important role in the inflammation and immune response caused by coccidiosis infection.
H Jin, Y Haicheng, Z Caiyun, Z Yong, W Jinrong   +4 more
doaj   +1 more source

Effects of Flavonoids on Cancer, Cardiovascular and Neurodegenerative Diseases: Role of NF-κB Signaling Pathway

International Journal of Molecular Sciences, 2023
Flavonoids are polyphenolic phytochemical compounds found in many plants, fruits, vegetables, and leaves. They have a multitude of medicinal applications due to their anti-inflammatory, antioxidative, antiviral, and anticarcinogenic properties ...
M. M. Barreca, R. Alessandro, C. Corrado
semanticscholar   +1 more source

Chicken telomerase reverse transcriptase mediates LMH cell pyroptosis by regulating the nuclear factor-kappa B signaling pathway

Poultry Science, 2022
: The activation of human telomerase reverse transcriptase is regulated by the nuclear factor kappa B (NF-κB) signaling pathway to various degrees to promote the occurrence and development of tumors.
Yong Xiang, Yun Yu, Qingbo Li, Jian Chen, Yu Li, Weisheng Cao   +5 more
doaj   +1 more source

IGF-1 and PDGF-bb Suppress IL-1β-Induced Cartilage Degradation through Down-Regulation of NF-κB Signaling: Involvement of Src/PI-3K/AKT Pathway [PDF]

PLoS ONE, 2011
Interleukin-1β (IL-1β) is a pro-inflammatory cytokine that plays a key role in the pathogenesis of osteoarthritis (OA). Growth factors (GFs) capable of antagonizing the catabolic actions of cytokines may have therapeutic potential in the treatment of OA.
Montaseri A., Busch F., Mobasheri A., Buhrmann C., Aldinger C., Rad J. S., Shakibaei M.   +6 more
openaire   +6 more sources

Phosphatidylethanolamine-binding protein 4 deficiency exacerbates carbon tetrachloride-induced liver fibrosis by regulating the NF-κB signaling pathway

Frontiers in Pharmacology, 2022
Liver fibrosis is a pathological process which can progress to hepatocirrhosis, even hepatocellular carcinoma. Phosphatidylethanolamine-binding protein 4 (PEBP4) is a secreted protein involved in regulating many molecular pathways, whereas its roles in ...
Qianqian Luo, Yuanyi Ling, Yuanyi Ling, Yufei Li, Xiaoqin Qu, Qiaoqing Shi, Shuangyan Zheng, Yanhong Li, Yonghong Huang, Yonghong Huang, Xiaoyan Zhou, Xiaoyan Zhou   +11 more
doaj   +1 more source

How to Inhibit Nuclear Factor-Kappa B Signaling: Lessons from Poxviruses

Pathogens, 2022
The Nuclear Factor-kappa B (NF-κB) family of transcription factors regulates key host inflammatory and antiviral gene expression programs, and thus, is often activated during viral infection through the action of pattern-recognition receptors and ...
Joshua B. Reus, Emily A. Rex, Don B. Gammon   +2 more
doaj   +1 more source

Role of the NF-κB signaling pathway in the pathogenesis of colorectal cancer.

Gene, 2020
The NF-κB signaling pathway is a key regulator of CRC cell proliferation, apoptosis, angiogenesis, inflammation, metastasis, and drug resistance. Over-activation of the NF-κB pathway is a feature of colorectal cancer (CRC).
Atena Soleimani, F. Rahmani, G. Ferns, Mikhail Ryzhikov, A. Avan, S. M. Hassanian   +5 more
semanticscholar   +1 more source