Results 111 to 120 of about 99,051 (206)
Granulocyte-macrophage colony-stimulating factor activates the transcription of nuclear factor kappa B and induces the expression of nitric oxide synthase in a skin dendritic cell line. [PDF]
, 2001 Nitric oxide (NO) produced by skin dendritic cells and keratinocytes plays an important role in skin physiology, growth and remodelling. Nitric oxide is also involved in skin inflammatory processes and in modulating antigen presentation (either enhancing
Carvalho, AP +5 more
core
Brazilian Journal of Otorhinolaryngology, 2011 Glucocorticoids are considered the main treatment option for nasal polyps, but their effect is only recently being understood. AIM: To evaluate whether fluticasone propionate (FP) inhibits the inflammatory process induced by TNF-alpha in vitro, and to ...
Fabiana Valera +6 more
doaj +1 more source
Interleukin-17A upregulates receptor activator of NF-kappaB on osteoclast precursors. [PDF]
, 2010 IntroductionThe interaction between the immune and skeletal systems is evidenced by the bone loss observed in autoimmune diseases such as rheumatoid arthritis. In this paper we describe a new mechanism by which the immune cytokine IL-17A directly affects
Adamopoulos, Iannis E +7 more
core +1 more source
PLoS ONE, 2009 BackgroundIn response to viral infection, the innate immune system recognizes viral nucleic acids and then induces production of proinflammatory cytokines and type I interferons (IFNs).
Hiroyasu Konno +15 more
doaj +1 more source
Role of NF-kappaB in thyroid cancer.
Molecular and cellular endocrinology, 2009 Thyroid cancer is the most common neoplasia of the endocrine system and accounts for approximately 1% of all newly diagnosed cancer cases. Its incidence has rapidly grown over the past few decades. Although most thyroid carcinomas are of the well-differentiated papillary histology, and respond well to treatment with surgical resection followed by ...
PACIFICO, FRANCESCO MARIA +1 more
openaire +6 more sources
TNFAIP3 interacting protein 2 relieves lipopolysaccharide (LPS)-induced inflammatory injury in endometritis by inhibiting NF-kappaB activation. [PDF]
Immun Inflamm Dis, 2023 Qian X, Wang Y, Li X, Li Y, Li L.
europepmc +1 more source
Circuitry of nuclear factor κB signaling [PDF]
, 2006 Over the past few years, the transcription factor nuclear factor (NF)-κB and the proteins that regulate it have emerged as a signaling system of pre-eminent importance in human physiology and in an increasing number of pathologies. While NF-κB is present
Baltimore, David, Hoffmann, Alexander
core
Intravenous Injection of PEI-Decorated Iron Oxide Nanoparticles Impacts NF-kappaB Protein Expression in Immunologically Stressed Mice. [PDF]
Nanomaterials (Basel), 2023 Schwarz C +3 more
europepmc +1 more source
Biochemical pharmacology, 2001 Camptothecin (CPT) and derivatives are topoisomerase I poisons currently used as anticancer drugs. Their cytotoxicity is maximal for cells in S phase. Using asynchronous and S phase-synchronized HeLa cells, we showed that both the nuclear factor-kappaB (NF-kappaB) activation and its transcriptional activity, induced by CPT treatment, are enhanced in S ...
Habraken, Yvette +2 more
openaire +2 more sources
An Update on the Multifaceted Role of NF-kappaB in Endometriosis. [PDF]
Int J Biol Sci, 2022 Liu Y, Wang J, Zhang X.
europepmc +1 more source