Results 161 to 170 of about 6,021 (217)

Presenilin: A Multi-Functional Molecule in the Pathogenesis of Alzheimer's Disease and Other Neurodegenerative Diseases. [PDF]

Int J Mol Sci
Sun Y, Islam S, Michikawa M, Zou K.
europepmc   +1 more source

Caspase-8, association with Alzheimer\u27s disease and functional analysis of rare variants [PDF]

, 2017
Cruchaga, Carlos, et al.,, Lord, Jenny
core   +1 more source

Design of two single-domain introbodies to reduce intracellular Aβ production [PDF]

, 2014
Cañete Ríos, Manuel, Universitat Autònoma de Barcelona. Facultat de Biociències   +1 more
core  

Post-translational regulation of the low-density lipoprotein receptor provides new targets for cholesterol regulation. [PDF]

Biochem Soc Trans
Aldworth H, Hooper NM.
europepmc   +1 more source

Identification of domains in Plasmodium falciparum proteins of unknown function using DALI search on AlphaFold predictions. [PDF]

Sci Rep
Behrens HM, Spielmann T.
europepmc   +1 more source

The Curious Case of a Heterozygous Loss-of-Function PSEN1 variant associated with Early-Onset Alzheimer’s Disease

Ruiz IS, Serneels L, Craessaerts K, Goate A, Annaert W, Gutierrez LC, Shi Y, Sheikh-Bahaei N, Jen JC, Ramos EM, Campan M, Ward PM, Magaki S, Bartlone K, Vinters HV, Craig DW, Ringman JM, Strooper B.   +17 more
europepmc   +1 more source

Gnb5 is a negative regulator of the BACE1-mediated Aβ generation and ameliorates cognitive deficits in a mouse model of Alzheimer's disease. [PDF]

PLoS Biol
Chen S, Zhou J, Wang S, Chen E, Zhuang K, Lin R, Liang C, Can D, Li H, Li J, Zhang J.   +10 more
europepmc   +1 more source

The N-terminal PA domains of signal-peptide-peptidase-like 2 (SPPL2) proteases impact on TNFα cleavage. [PDF]

Commun Biol
Schlosser C, Sharrouf K, Papadopoulou AA, Haug-Kröper M, Singh S, Johler M, Pettinger J, Horn H, Koch M, Hoeppner S, Fluhrer R.   +10 more
europepmc   +1 more source

Anti-Inflammatory Peptide Prevents Aβ_25-35-Induced Inflammation in Rats via Lipoxygenase Inhibition. [PDF]

Cells
Yadav Y, Anwar M, Sharma H, Jain S, Sharma U, Haldar P, Dey AB, Dey S.   +7 more
europepmc   +1 more source

Identification of lysosome-related hub genes as potential biomarkers and immune infiltrations of moyamoya disease by multiple bioinformatics methods and machine-learning strategies. [PDF]

Heliyon
Li W, Zhao X, Fu J, Cheng L.
europepmc   +1 more source