Results 101 to 110 of about 36,040 (208)

Deacetylation of SRF catalyzed by SIRT7 protects against abdominal aortic aneurysm formation

open access: yesExperimental and Molecular Medicine
Abdominal aortic aneurysm (AAA) is a life-threatening cardiovascular disease for which no effective pharmacological treatments exist. Histone deacetylases (HDACs) have emerged as critical regulators of cardiovascular pathophysiology; however, the ...
Yacheng Xiong   +9 more
doaj   +1 more source

Control of NAD+ homeostasis by autophagic flux modulates mitochondrial and cardiac function

open access: yesThe EMBO Journal
Impaired autophagy is known to cause mitochondrial dysfunction and heart failure, in part due to altered mitophagy and protein quality control. However, whether additional mechanisms are involved in the development of mitochondrial dysfunction and heart ...
Quanjiang Zhang   +11 more
doaj   +1 more source

ENZYMATIC SYNTHESIS OF NICOTINAMIDE MONONUCLEOTIDE

open access: yesJournal of Biological Chemistry, 1957
J, PREISS, P, HANDLER
openaire   +2 more sources

Towards personalized nicotinamide mononucleotide (NMN) supplementation:Nicotinamide adenine dinucleotide (NAD) concentration

open access: yes
Nicotinamide mononucleotide (NMN) is a precursor of nicotinamide adenine dinucleotide (NAD), which declines with age. Supplementation of NMN has been shown to improve blood NAD concentration. However, the optimal NMN dose remains unclear.
Pendse, Sohal   +11 more
core   +2 more sources

Identification of the Escherichia coli Nicotinic Acid Mononucleotide Adenylyltransferase Gene

open access: yes, 2000
The gene ( ybeN ) coding for nicotinate mononucleotide adenylyltransferase, an NAD(P) biosynthetic enzyme, has been identified and overexpressed in Escherichia coli .
Cynthia Kinsland   +2 more
core   +1 more source

supplementary material for paper "PEGylated nicotinamide mononucleotide facilitated efficient renal uptake and inhibited ferroptosis in acute kidney injury through ACAA1-PRDX5-mediated connection of peroxisome and mitochondria"

open access: yes
supplementary material for paper "PEGylated nicotinamide mononucleotide facilitated efficient renal uptake and inhibited ferroptosis in acute kidney injury through ACAA1-PRDX5-mediated connection of peroxisome and ...
Li, Qingyu
core   +1 more source

Restorin® NR is a Highly Efficient NAD+ Precursor

open access: yesDrug Design, Development and Therapy
Brett Weiss,1 Rui Cao,1 Yongzheng Liu,2,3 Jiaqi Chen,2,4 George L Marshall11Seragon Biosciences, Irvine, CA, USA; 2Sinopharm-Seragon Biosciences, Beijing, People’s Republic of China; 3School of Medicine, Tsinghua University, Beijing, People’s Republic of
Weiss B   +4 more
doaj  

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