Results 21 to 30 of about 36,040 (208)

Precursor comparisons for the upregulation of nicotinamide adenine dinucleotide. Novel approaches for better aging

Aging Medicine, 2021
Nicotinamide adenine dinucleotide (NAD) is a coenzyme found in every human cell and regulates a number of systems across multiple cellular compartments and tissue types via an endogenous and exogenous influence.
Raymond D. Palmer, Magdy Mahmoud Elnashar, Mauro Vaccarezza   +2 more
doaj   +1 more source

Nicotinamide Mononucleotide Alleviates LPS-Induced Inflammation and Oxidative Stress via Decreasing COX-2 Expression in Macrophages

Frontiers in Molecular Biosciences, 2021
Macrophage activation is an important process in controlling infection, but persistent macrophage activation leads to chronic inflammation and diseases, such as tumor progression, insulin resistance and atherosclerosis.
Jing Liu, Zhaoyun Zong, Wenhao Zhang, Yuling Chen, Xueying Wang, Jie Shen, Changmei Yang, Xiaohui Liu, Haiteng Deng   +8 more
doaj   +1 more source

Effect of a mixture of caffeine and nicotinamide on the solubility of vitamin (B2) in aqueous solution [PDF]

, 2006
The effect of caffeine (CAF) and nicotinamide (NMD) on the solubility of a vitamin B2 derivative (FMN) has been evaluated for mixtures containing either a single hydrotrope (CAF or NMD) or the two hydrotropes simultaneously.
Davies, David B., Hernandez Santiago, A.A., Evstigneev, V.P., Evstigneev, M.P.   +3 more
core   +1 more source

Nicotinamide Mononucleotide Supplementation [PDF]

, 2021
Vascular cognitive impairment (VCI) is a major cause of dementia among elderly individuals. Understanding molecular mechanisms behind vascular aging is essential to develop novel interventional strategies for the treatment and prevention of VCI.
openaire   +1 more source

A Novel NAD-RNA Decapping Pathway Discovered by Synthetic Light-Up NAD-RNAs

Biomolecules, 2020
The complexity of the transcriptome is governed by the intricate interplay of transcription, RNA processing, translocation, and decay. In eukaryotes, the removal of the 5’-RNA cap is essential for the initiation of RNA degradation.
Florian Abele, Katharina Höfer, Patrick Bernhard, Julia Grawenhoff, Maximilian Seidel, André Krause, Sara Kopf, Martin Schröter, Andres Jäschke   +8 more
doaj   +1 more source

Nicotinamide phosphoribosyltransferase/visfatin does not catalyze nicotinamide mononucleotide formation in blood plasma. [PDF]

PLoS ONE, 2011
Nicotinamide (Nam) phosphoribosyltransferase (NAMPT) is the rate-limiting enzyme in mammalian NAD synthesis, catalyzing nicotinamide mononucleotide (NMN) formation from Nam and 5-phosphoribosyl 1-pyrophosphate (PRPP).
Nobumasa Hara, Kazuo Yamada, Tomoko Shibata, Harumi Osago, Mikako Tsuchiya   +4 more
doaj   +1 more source

Synthesis and detection of nicotinamide mononucleotide and its application in animal production

Siliao yanjiu, 2023
Nicotinamide mononucleotide is one of the key precursors for the generation of nicotinamide adenine dinucleotide. NAD+ is a redox coenzyme, widely involved in various biological effects such as intracellular energy metabolism, DNA repair, signal ...
ZHOU Chang-hong, PENG Hong-xing, LIU Xiao-qing, TAO Jian-jun   +3 more
doaj  

NAD+ Repletion Rescues Female Fertility during Reproductive Aging

Cell Reports, 2020
Summary: Reproductive aging in female mammals is an irreversible process associated with declining oocyte quality, which is the rate-limiting factor to fertility. Here, we show that this loss of oocyte quality with age accompanies declining levels of the
Michael J. Bertoldo, Dave R. Listijono, Wing-Hong Jonathan Ho, Angelique H. Riepsamen, Dale M. Goss, Dulama Richani, Xing L. Jin, Saabah Mahbub, Jared M. Campbell, Abbas Habibalahi, Wei-Guo Nicholas Loh, Neil A. Youngson, Jayanthi Maniam, Ashley S.A. Wong, Kaisa Selesniemi, Sonia Bustamante, Catherine Li, Yiqing Zhao, Maria B. Marinova, Lynn-Jee Kim, Laurin Lau, Rachael M. Wu, A. Stefanie Mikolaizak, Toshiyuki Araki, David G. Le Couteur, Nigel Turner, Margaret J. Morris, Kirsty A. Walters, Ewa Goldys, Christopher O’Neill, Robert B. Gilchrist, David A. Sinclair, Hayden A. Homer, Lindsay E. Wu   +33 more
doaj   +1 more source

Nicotinamide mononucleotide: a potential effective natural compound against insulin resistance

, 2021
Recently, a study published in Science by Yoshino et al.1 reported on a randomized, placebo-controlled, double-blind clinical trial to examine the effects of a 10-week nicotinamide mononucleotide (NMN) administration on human metabolism in 25 ...
Roos, Julian, Pamela Fischer-Posovszky, Julia Zinngrebe, Fischer-Posovszky, Pamela, Zinngrebe, Julia, Julian Roos   +5 more
core   +1 more source

Pyridine Metabolism and Trigonelline Synthesis in Leaves of the Mangrove Legume trees ) and

Natural Product Communications, 2011
The aim of this study was to reveal the pyridine metabolism in leaves of two mangrove legumes, Derris indica (= Millettia pinnata or Pongamia pinnata ) and Caesalpinia crista.
Yuling Yin, Hamako Sasamoto, Hiroshi Ashihara   +2 more
doaj   +1 more source