Results 51 to 60 of about 13,531,604 (176)
Nicotinamide N-methyltransferase as a potential marker for cancer
Neoplasma, 2018 Cancer is the main leading cause of death in the world, although it has been made noteworthy advances in cancer research in the past decades. Early detection of cancer is extremely important in improving the chances of successful therapy. Thus, it is urgently needed to make further efforts to explore novel tumor markers for treatment.
X M, Lu, H, Long
openaire +3 more sources
Expression of Nicotinamide N-Methyltransferase (E.C. 2.1.1.1) in the Parkinsonian Brain [PDF]
Journal of Neuropathology & Experimental Neurology, 2002 Nicotinamide N-methyltransferase (NNMT) has been proposed as a link between the environmental and genetic factors of Parkinson disease (PD). Therefore, we explored the hypothesis that high levels of NNMT expression may predispose to the development of PD.
Richard B, Parsons +4 more
openaire +2 more sources
Identification of Biological Functions and Prognostic Value of NNMT in Oral Squamous Cell Carcinoma
Biomolecules, 2022 Background: Nicotinamide N-methyltransferase (NNMT) is a metabolic enzyme that catalyzes the methylation of nicotinamide (NAM) to generate 1-methyl nicotinamide (MNAM).
Weixian Zhang +11 more
doaj +1 more source
Nicotinamide-N-Methyltransferase gene rs694539 variant and migraine risk [PDF]
The Journal of Headache and Pain, 2016 Migraine is a common neurovascular disorder affecting 10 to 20 % of the world population usually subdivided into migraine with auro (MA) and migraine without auro (MO). Homocysteine is involved in the pathophysiology of a number of neurological disorders.
Ergul, Emel +4 more
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Kinetic Mechanism of Nicotinamide N-Methyltransferase.
, 2018 Nicotinamide N-methyltransferase (NNMT) catalyzes the transfer of a methyl group from S-adenosylmethionine (SAM) to nicotinamide, pyridine, and other structural analogues.
Thompson, Paul R, Loring, Heather S.
core +1 more source
Nicotinamide N-methyltransferase protein expression in renal cell cancer [PDF]
Journal of Zhejiang University SCIENCE B, 2010 To understand the function of nicotinamide N-methyltransferase (NNMT) protein as tumor biomarker in renal carcinoma.Recombinant NNMT protein was used to prepare monoclonal antibodies by hybridoma technique. The diagnostic and prognostic function of NNMT protein in renal carcinoma was evaluated by analyzing 74 renal cancer tissues through ...
Jun, Zhang +4 more
openaire +2 more sources
Correction to Discovery of Bisubstrate Inhibitors of Nicotinamide N‑Methyltransferase (NNMT)
, 2018 Correction to Discovery of Bisubstrate Inhibitors of Nicotinamide N‑Methyltransferase ...
Fengling Li (176389) +9 more
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Citrullination Inactivates Nicotinamide-N-methyltransferase
, 2018 Nicotinamide-N-methyl transferase (NNMT) catalyzes the irreversible methylation of nicotinamide (NAM) to form N-methyl nicotinamide (MeNAM) using SAM as a methyl donor.
Weerapana, Eranthie +6 more
core +1 more source
Biological Reviews, EarlyView.ABSTRACT Heat stress (HS) is an increasing threat to male reproductive health, disrupting spermatogenesis through complex and interdependent cellular responses within the seminiferous epithelium. Although excessive reactive oxygen species (ROS) production is a hallmark of HS, ROS also act as central regulators of cell fate decisions beyond their role ...
Ribrio Ivan Tavares Pereira Batista
wiley +1 more source
Hepatology Communications, 2017 Iron overload causes the generation of reactive oxygen species that can lead to lasting damage to the liver and other organs. The goal of this study was to identify genes that modify the toxicity of iron overload.
Tiago Koppe +9 more
doaj +1 more source