Results 91 to 100 of about 97,079 (192)

Insights into channel function via channel dysfunction [PDF]

open access: yes, 2003
The nicotinic synapse has been a touchstone for advances in neuroscience ever since Jean Nicot, the French ambassador to Portugal, sent some tobacco seeds home to Paris in 1550 with a note that the New World plant had interesting effects when smoked. Now
Leite, John F.   +2 more
core  

Photoaffinity labeling coupled to MS to identify peptide biological partners: Secondary reactions, for better or for worse?

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Affinity photolabeling is a smart method to study noncovalent and transient interactions and provide a submolecular picture of the contacts between interacting partners. In this review, we will focus on the identification of peptide partners using photoaffinity labeling coupled to mass spectrometry in different contexts such as in vitro with a
Astrid Walrant, Emmanuelle Sachon
wiley   +1 more source

Practical Applications of Secondary/Extractive Electrospray Ionization (SESI): A Versatile Tool for Real‐Time Chemical Analysis

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT In the 1980s, researchers discovered the remarkable ability of electrospray plumes to effectively ionize gas‐phase molecules via secondary ionization. Around 20 years later—coinciding with the ambient mass spectrometry revolution—secondary electrospray ionization (SESI) and extractive electrospray ionization (EESI) coupled to mass spectrometry
Xin Luo   +5 more
wiley   +1 more source

Reactivity of Imidazole‐ and Pyridine‐Carboxaldehydes for Gem‐Diol and Hemiacetal Generation: Theoretical and Experimental Insights

open access: yesChemistryOpen, EarlyView.
The generation of the gem‐diol and hemiacetal forms using pyridine‐ and imidazole‐carboxaldehyde isomers in different chemical environments was studied by NMR spectra and combined with theoretical calculations. Unlike aprotic solvents, protic ones, as water and methanol, favored the generation of the gem‐diol and hemiacetal structures.
Ayelén F. Crespi   +5 more
wiley   +1 more source

Visible Light–Induced Decarboxylative Radical Addition of Heteroaromatic Carboxylic Acids to Alkenes at Room Temperature in Two‐Molecule Photoredox System

open access: yesChemistryOpen, EarlyView.
The photoinduced decarboxylative radical addition of aryl carboxylic acids, including heteroaromatic carboxylic acids, to electron‐deficient alkenes is achieved in a two‐molecule photoredox system using a combination of biphenyl and 9,10‐dicyanoanthracene without heating or base.
Daisuke Suzuki   +5 more
wiley   +1 more source

Effect of Exogenous Application of Nicotinic Acid on Morpho-Physiological Characteristics of Hordeum vulgare L. under Water Stress. [PDF]

open access: yesPlants (Basel), 2022
Farooq TH   +9 more
europepmc   +1 more source

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