Results 81 to 90 of about 60,608 (292)

5-Trifluoromethoxy-substituted Nicotinic Acid, Nicotinamide and Related Compounds

Журнал органічної та фармацевтичної хімії
A practical and convenient method for synthesizing nicotinic acid and nicotinamide with the trifluoromethoxy group in position 5 of the ring has been developed.
Taras M. Sokolenko, Yurii L. Yagupolskii
doaj   +1 more source

Pyridine nucleotide synthesis by rat adipose tissue in vitro

Journal of Lipid Research, 1967
The synthesis of NAD and NADP by rat adipose tissue was measured in vitro. Nicotinamide-7-14C and NaH232PO4 were incorporated together into NAD with a 32P/14C ratio of 1.82 and nicotinic-7-14C acid and NaH232PO4 with a ratio of 1.94.
Richard W. Hanson, Zigmund Z. Ziporin
doaj   +1 more source

Figure S2 from Discovery of a Highly Selective NAMPT Inhibitor That Demonstrates Robust Efficacy and Improved Retinal Toxicity with Nicotinic Acid Coadministration

, 2023
Genshi Zhao, Colin F. Green, Yu‐Hua Hui, Lourdes Prieto, R.L. Shepard, Sucai Dong, Tao Wang, Bo Tan, Xueqian Gong, Lisa Kays, Robert L. Johnson, Wenjuan Wu, Shobha Bhattachar, Miriam Del Prado, James R. Gillig, Maria-Carmen Fernandez, Ken D. Roth, Sean G. Buchanan, Ming‐Shang Kuo, Sandaruwan Geeganage, Timothy P. Burkholder   +20 more
openalex   +1 more source

Development of an Innovative and Functional Yerba Mate—Lychee Beverage: Sensory and Physicochemical Characteristics

Food Safety and Health, EarlyView.
A mixed beverage of yerba mate and lychee was developed and optimized. The 70:30 lychee‐to‐mate formulation provided the best balance of antioxidant activity and consumer acceptance, highlighting its potential as a functional beverage. ABSTRACT The development of functional beverages that combine bioactive compounds with sensory appeal is of growing ...
Marcela Moreira Terhaag, Leonel Vinícius Constantino, Lycio Shinji Watanabe, Tiago Bervelieri Madeira, Suzana Lucy Nixdorf, Marta de Toledo Benassi, Fábio Yamashita, Sandra Helena Prudencio   +7 more
wiley   +1 more source

Mechanisms of spinal glial activation in chemotherapy‐induced peripheral neuropathy: Focus on microglia and astrocytes

Ibrain, EarlyView.
Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley   +1 more source

Solubility and thermodynamic parameters of nicotinic acid in different solvents

, 2023
Marcel Silveira, Diego A. Mayer, Evertan A. Rebelatto, Pedro Henrique Hermes de Araújo, J. Vladimir Oliveira   +4 more
openalex   +2 more sources

Molecular imprinting for neurology: Materials, applications, and limitations

Ibrain, EarlyView.
Molecularly imprinted materials: diagnostic, therapeutic and research applications in neurology. Molecularly imprinted materials offer high specificity and affinity for target molecules in neurological applications. This review highlights their synthesis, characterisation, and use in diagnostics, research and therapeutics.
Xiaohan Ma, Yingqi Ma, Claudia Marino, Alessandro Poma   +3 more
wiley   +1 more source

Profiling of the Contents of Amino Acids, Water-Soluble Vitamins, Minerals, Sugars and Organic Acids in Turkish Hazelnut Varieties

Polish Journal of Food and Nutrition Sciences, 2018
Proximate composition, profiles of amino acids, sugars, organic acids, vitamins and minerals of fourteen Turkish hazelnut varieties harvested in 2013 and 2014 were investigated.
Taş Neslihan Göncüoğlu, Gökmen Vural   +1 more
doaj   +1 more source

Weizmannia coagulans XY2 Mitigates Copper Neurotoxicity via Gut–Brain Axis Modulation of Tryptophan Metabolism and Oxidative‐Inflammatory Crosstalk

iMetaOmics, EarlyView.
Copper interferes with tryptophan metabolism and 5‐HT levels by modulating intestinal flora. Intestinal barrier breakdown and inflammatory response trigger nerve damage under copper exposure. W. coagulans XY2 alleviates copper‐induced neurotoxicity by targeting a multi‐dimensional “tryptophan metabolism‐antioxidant defense‐gut‐brain axis” network.
Yufang Gao, Xiaodong Zheng, Fujie Yan
wiley   +1 more source

Stratification of chronic rhinosinusitis with nasal polyps by distinct sinonasal microbial communities and their clinical and pathological correlations

iMetaOmics, EarlyView.
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heterogeneous inflammatory condition. Dysbiosis is commonly observed. This study identified distinct sinonasal microbial communities in CRSwNP patients and explored their clinical and pathological associations. Two distinct microbial communities were identified: community type 1 (CT1), dominated by
Bixing Fang, Yanmin Liu, Qing Bao, Lin Sun, Hexin Chen, Qingxiang Meng, Linyi Jiao, Xiaoyan Ye, Jian Li, Tao Ding, Chunwei Li   +10 more
wiley   +1 more source