Results 41 to 50 of about 872,363 (287)

Nicotinic-Acid-Ornamented Tetrameric Rare-Earth-Substituted Phospho(III)tungstates with the Coexistence of Mixed Keggin/Dawson Building Blocks and Its Honeycomb Nanofilm for Detecting Toxins

, 2021
A fascinating class of nicotinic-acid-ornamented tetrameric rare-earth (RE)-substituted phospho­(III)­tungstates [NH2(CH3)2]10Na4H8[RE2(NA)­(HNA)­(H2O)6(W2O4)­(β-H2P2IIIW13O49)­(α-HPIIIW9O33)]2·22 H2O [RE = Nd3+ (1-Nd), Tb3+ (2-Tb), Dy3+ (3-Dy), Ho3+ (4 ...
Lijuan Chen, Junwei Zhao (1444117), Lulu Liu (793645), Lulu Liu, Lijuan Chen (150349), Yanzhou Li (1726096), Guoping Liu, Guoping Liu (4584502), Tiantian Gong, Yanzhou Li, Junwei Zhao, Tiantian Gong (11086178)   +11 more
core   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Contribution of gut microbiomes and their metabolomes to the performance of Dorper and Tan sheep

Frontiers in Microbiology, 2022
BackgroundLivestock is an excellent source of high nutritional value protein for humans; breeding livestock is focused on improving meat productivity and quality. Dorper sheep is a distinguished breed with an excellent growth performance, while Tan sheep
Yuhao Ma, Xue Yang, Guoying Hua, Xiaotian Deng, Tianlan Xia, Xinhai Li, Dengzhen Feng, Xuemei Deng   +7 more
doaj   +1 more source

NACHO Engages N-Glycosylation ER Chaperone Pathways for α7 Nicotinic Receptor Assembly

Cell Reports, 2020
Summary: The α7 nicotinic acetylcholine receptor participates in diverse aspects of brain physiology and disease. Neurons tightly control α7 assembly, which relies upon NACHO, an endoplasmic reticulum (ER)-localized integral membrane protein.
Hae-Jin Kweon, Shenyan Gu, Emily Witham, Madhurima Dhara, Hong Yu, Elodie Desuzinges Mandon, Anass Jawhari, David S. Bredt   +7 more
doaj   +1 more source

The effects of solvents and structure on the electronic absorption spectra of the isomeric pyridine carboxylic acid N-oxides [PDF]

Chemical Industry and Chemical Engineering Quarterly, 2013
The ultraviolet absorption spectra of the carboxyl group of three isomeric pyridine carboxylic acids N-oxides (picolinic acid N-oxide, nicotinic acid N-oxide and isonicotinic acid N-oxide) were determined in fourteen solvents in the wavelength range ...
Drmanić Saša Ž., Nikolić Jasmina B., Marinković Aleksandar D., Šekularac Gavrilo M., Jovanović Bratislav Ž.   +4 more
doaj   +1 more source

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source

Charting Morphotoxicity With Complementary Embryo Models

Advanced Healthcare Materials, EarlyView.
Three human embryo models of the peri‐implantation stages are exposed to a library of compounds. The (toxic) effects of the compounds are analyzed through automated image analysis pipelines. By evaluating the differential responses of the embryo models, this study underscores the importance of testing complementary embryo models to achieve robust and ...
Dorian G. Luijkx, Pauline L. Balder, Romy M. L. Verhagen, Vinidhra Shankar, Barry Jutten, Pinak Samal, Timo Rademakers, Clemens A. van Blitterswijk, Stefan Giselbrecht, Erik J. Vrij   +9 more
wiley   +1 more source

HDL Functions—Current Status and Future Perspectives

Biomolecules, 2023
Cardiovascular disease (CVD) is the leading cause of death in Western countries. A low HDL-C is associated with the development of CVD. However, recent epidemiology studies have shown U-shaped curves between HDL-C and CVD mortality, with paradoxically ...
Yasuhiro Endo, Masanori Fujita, Katsunori Ikewaki   +2 more
doaj   +1 more source

Changes in conformation and subcellular distribution of alpha(4)beta(2) nicotinic acetylcholine receptors revealed by chronic nicotine treatment and expression of subunit chimeras [PDF]

, 2002
Chronic exposure to nicotine, as occurs during tobacco smoking, is one of several factors that have been reported to cause an upregulation of neuronal nicotinic acetylcholine receptors (nAChRs).
Harkness, PC, Millar, NS
core  

Distribution of Nicotinic Receptors in the Human Brain: Quantitative Autoradiography Using 3H-Nicotine

, 1988
Several studies showed clearly that the mammalian central nervous system possess nicotinic receptors. Recently, using membrane receptor binding studies the regional distribution of 3H-nicotine and/or H-acetylcholine binding sites in the human brain has ...
Abdu Adem, Per-Göran Gillberg, Gillberg, P-G, Jossan, SS, Nordberg, A, Sukhwinder S. Jossan, Adem, A, Sara, V, Vicki Sara, Agneta Nordberg   +9 more
core   +1 more source