The complexation reactions of nido-carboranyl amidine 10-PrNHC(Et)=HN-7,8-C2B9H11 with different nickel(II) phosphine complexes such as [(PR2R’)2NiCl2] (R = R’ = Ph, Bu; R = Me, R’ = Ph) were investigated.
Marina Yu. Stogniy +4 more
doaj +1 more source
Carborane confined nanoparticles for boron neutron capture therapy: Improved stability, blood circulation time and tumor accumulation [PDF]
Carborane confined nanoparticles based on the core cross-linked and boron-containing micelles (CL micelles) were prepared using the radical polymerization of poly(ethylene glycol)-block-poly(lactide) copolymer (PEG-b-PLA), which contained an acetal group
Nagasaki Yukio +5 more
core +1 more source
Closo-o-carboranyl compounds bearing the ortho-type perfectly distorted or planar terphenyl rings (closo-DT and closo-PT, respectively) and their nido-derivatives (nido-DT and nido-PT, respectively) were synthesized and fully characterized using ...
Hyunhee So +7 more
doaj +1 more source
Half-Sandwich Nickelacarboranes Derived from [7-(MeO(CH2)2S)-7,8-C2B9H11]−
New carboranyl thioethers 1-MeO(CH2)nS-1,2-C2B10H11 (n = 2, 3) were prepared by the alkylation of the trimethylammonium salt of 1-mercapto-ortho-carborane with 1-bromo- 2-methoxyethane and 1-bromo-3-methoxypropane, respectively.
Dmitriy K. Semyonov +3 more
doaj +1 more source
Advances in Diclofenac Derivatives: Exploring Carborane-Substituted N-Methyl and Nitrile Analogs for Anticancer Therapy. [PDF]
By N‐methylation, the intramolecular lactam formation in carborane‐substituted diclofenac analogs is prevented, yielding a series of open‐chain derivatives alongside with their phenyl analogs exhibiting anticancer activity and thus offering a promising avenue for future drug development. This study explores the anticancer potential of N‐methylated open‐
Selg C +12 more
europepmc +2 more sources
Boron-containing delocalised lipophilic cations for the selective targeting of cancer cells [PDF]
Correction for “Boron-containing delocalised lipophilic cations for the selective targeting of cancer cells” by Gianpiero Calabrese et al., Med. Chem. Commun., 2017, 8, 67–72.
Calabrese, Gianpiero +6 more
core +1 more source
“Free of Base” Sulfa-Michael Addition for Novel o-Carboranyl-DL-Cysteine Synthesis
The sulfa-Michael addition reaction was applied for the two-step synthesis of o-carboranyl cysteine 1-HOOCCH(NH2)CH2S-1,2-C2B10H11 from the trimethylammonium salt of 1-mercapto-o-carborane and methyl 2-acetamidoacrylate.
Julia Laskova +5 more
doaj +1 more source
Pharmacokinetics of core-polymerized boron-conjugated micelles designed for boron neutron capture therapy for cancer [PDF]
journal ...
Horiguchi Yukichi +8 more
core +1 more source
Novel Isoniazid-Carborane Hybrids Active In Vitro against Mycobacterium tuberculosis
Tuberculosis (TB) is a severe infectious disease with high mortality and morbidity. The emergence of drug-resistant TB has increased the challenge to eliminate this disease.
Daria Różycka +9 more
doaj +1 more source
Chelating N-heterocyclic carbene-carboranes offer flexible ligand coordination to IrIII, RhIII and RuII: effect of ligand cyclometallation in catalytic transfer hydrogenation [PDF]
Imidazolium salts linked by an ethyl tether to closo-dicarbadodecaboranes were reacted with [IrCp*Cl2]2, [RhCp*Cl2]2 or [Ru(p-cymene)Cl2]2 in the presence of Ag2O to prepare complexes of the type [MCp*(NHC)Cl2] (M = Ir, Rh; NHC = N-heterocyclic carbene ...
Aher +54 more
core +1 more source

