Results 101 to 110 of about 252,458 (275)

Revealing Temperature‐Driven Interfacial Reactions of Succinonitrile in PEO‒LiTFSI Electrolytes and Suppressing Them via Dual PEDOT‐Based Interfacial Layers

open access: yesAdvanced Science, EarlyView.
Temperature‐driven interfacial reactions of succinonitrile in PEO‐LiTFSI electrolyte are revealed at both lithium and cathode interfaces, identifying cathode degradation as the dominant failure pathway. Dual PEDOT‐based interfacial protection suppresses these reactions, stabilizes both electrode interfaces, and enables durable wide‐temperature solid ...
Baskar Selvaraj   +9 more
wiley   +1 more source

Oral Actinomyces Species Exposure is Associated with Anxiety‐Like Behavior, Mitochondrial Remodeling, and Altered GABAergic Pathways

open access: yesAdvanced Science, EarlyView.
Oral exposure to cannabis‐associated Actinomyces species, particularly A. meyeri, is associated with anxiety‐like behavior in mice in the absence of detectable bacterial translocation or overt systemic inflammation. These findings support a potential oral‐brain metabolic axis involving candidate metabolites such as arginine and argininosuccinate ...
Tabinda Salman   +11 more
wiley   +1 more source

Synthesis of Highly Stable and Reactive Nitrile N‑Oxides and Their Application as Catalyst-Free Crosslinkers

open access: yes
Nitrile N-oxide-based click ligation is a very promising technique for polymer crosslinking due to the unique advantages of catalyst-free and byproduct-free reactions.
Ning Liu (168279)   +6 more
core   +1 more source

Molecular Electrocatalysis Coupled With a Palladium Membrane Reactor Affords Selective Nitrogen Reduction

open access: yesAdvanced Science, EarlyView.
A palladium membrane reactor delivers active hydrogen to homogeneous nickel terpyridine catalysts, which then selectively hydrogenate dinitrogen to ammonia. ABSTRACT Ammonia production is a cornerstone of modern industry and society, yet the conventional Haber–Bosch process accounts for nearly 2% of the global CO2 emissions. A promising and potentially
Morgan McKee   +11 more
wiley   +1 more source

Metabolic‐Redox Remodeling of Inflammatory Synovium by Mannose‐Modified Selenium Nanoparticles for Osteoarthritis Therapy

open access: yesAdvanced Science, EarlyView.
Elevated GLUT1‐driven glycolysis and disrupted selenoprotein‐dependent redox homeostasis drive osteoarthritic progression. Intra‐articular mannose‐modified selenium nanoparticles (M‐SeNPs) selectively target hypermetabolic synovial cells to reprogram aberrant glycolysis and restore endogenous antioxidant defenses.
Yu‐Qing Zou   +15 more
wiley   +1 more source

Interfacial Salt Redistribution Enables Rapid Atmospheric Water Harvesting in a Biomimetic Multi‐Layer Hygroscopic Membrane

open access: yesAdvanced Science, EarlyView.
A biomimetic multi‐layer hygroscopic membrane redistributes salt toward an air‐accessible nanofiber interface, enabling rapid interfacial deliquescence while a brush‐like hydrogel promotes efficient liquid transport and storage. By decoupling vapor capture from bulk water storage, the membrane achieves fast sorption kinetics and enables rapid‐cycling ...
Fu‐Yao Zhong   +8 more
wiley   +1 more source

H4K12 Lactylation Impairs Dopaminergic Neuron Energy Metabolism via the HIF‐1α/NDUFS1 Pathway in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
Lactate and H4K12la are elevated in Parkinson's disease. Mechanistically, p300‐mediated H4K12la enrichment at the HIF‐1α promoter upregulates HIF‐1α, which represses Ndufs1, impairing mitochondrial respiration and energy homeostasis in DA neurons.
Yingyao Liu   +15 more
wiley   +1 more source

Mn/Zn Bimetallic MOF‐Integrated Hydrogel Alleviates Excessive Mitochondrial Fission in BMSCs to Promote Osteoporotic Jawbone Repair

open access: yesAdvanced Science, EarlyView.
Excessive reactive oxygen species (ROS) and chronic inflammation impair bone marrow‐derived mesenchymal stem cells (BMSCs), contributing to poor healing in osteoporotic jawbone defect. The gelatin methacryloyl hydrogel loaded with manganese‐doped zeolitic imidazolate framework (Mn‐ZIF‐8@GelMA) promotes regeneration through redox regulation and ...
Xiayue Jin   +6 more
wiley   +1 more source

ChemInform Abstract: An Efficient Entry to 1,2-Benzisoxazoles via 1,3-Dipolar Cycloaddition of in situ Generated Nitrile Oxides and Benzyne.

open access: yes, 2010
An efficient protocol for the synthesis of a range of 1,2-benzisoxazoles using an improved 1,3-dipolar cycloaddition of nitrile oxides and benzyne is described.
Moses, J. E.   +13 more
core   +1 more source

AKAP1 Protects Retinal Ganglion Cells and Preserves Vision by Improving Mitochondrial and Synaptic Health in Glaucomatous Neurodegeneration

open access: yesAdvanced Science, EarlyView.
Intravitreal AAV2‐mediated AKAP1 restoration enhances mitochondrial fusion and biogenesis, improves bioenergetic capacity, and preserves mitochondrial integrity in glaucomatous RGCs. AKAP1 stabilizes presynaptic structure, maintaining synaptic protein expression, and limiting complement‐associated neuroinflammation.
Tonking Bastola   +10 more
wiley   +1 more source

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