Results 91 to 100 of about 4,572 (262)

Mechanistic Insights in the Mode of Action of Bifunctional Pyrrolidine-Squaramide-derived Organocatalysts [PDF]

, 2016
The modes of catalytic action of three squaramide-derived bifunctional organocatalysts have been investigated using DFT methods. The [5+2] cycloaddition between oxidopyrilium ylides and enals has been used as model reaction.
Carrillo Fernández, María Luisa, Jørgensen, Karl Anker, Merino, Pedro, Reyes Martín, Efraim, Roca-López, David, Uria Pujana, Uxue, Vicario Hernando, José Luis   +6 more
core   +2 more sources

A Decade of Progress: Review of the Synthesis of Dibenzo[b,f]oxepines

The Chemical Record, Volume 25, Issue 10, October 2025.
This review summarizes recent advances in dibenzo[b,f]oxepine synthesis, highlighting medicinal and materials applications. It discusses classical and modern methods, including cross‐coupling, intramolecular cyclizations, and diversification strategies, emphasizing efficiency, selectivity, and sustainability. Emerging trends such as greener approaches,
Gabriel Pereira da Costa, Bruna Rafaella Schneider, Angelita Manke Barcellos, Liane Krolow Soares, Rafael Centurião Brinkerhoff, Fernanda Piecha Ludwig, Alex Fabiani Claro Flores   +6 more
wiley   +1 more source

Nitro-Arachidonic Acid Prevents Angiotensin II-Induced Mitochondrial Dysfunction in a Cell Line of Kidney Proximal Tubular Cells.

PLoS ONE, 2016
Nitro-arachidonic acid (NO2-AA) is a cell signaling nitroalkene that exerts anti-inflammatory activities during macrophage activation. While angiotensin II (ANG II) produces an increase in reactive oxygen species (ROS) production and mitochondrial ...
Beatriz Sánchez-Calvo, Adriana Cassina, Natalia Rios, Gonzalo Peluffo, José Boggia, Rafael Radi, Homero Rubbo, Andres Trostchansky   +7 more
doaj   +1 more source

Exploiting the Reactivity of 1,2-Ketoamides: Enantioselective Syn-thesis of Functionalized Pyrrolidines and Pyrrolo-1,4-benzodiaze-pine-2,5-diones

, 2015
International audienceA new strategy for the synthesis of optically active pyrrolo[ 1,4]benzo- diazepine-2,5-diones has been developed. The approach is based on an initial Michael addition of functionalized 1,2-ketoamides on nitroalkenes, with a ...
Acosta, Paola, Becerra, Diana, Bonne, Damien, Constantieux, Thierry, Goudedranche, Sébastien, Quiroga, Jairo, Rodriguez, Jean   +6 more
core   +4 more sources

Bifunctional Organocatalysts and Brønsted Bases in Cooperative Catalysis for the Asymmetric [4 + 2] Cycloaddition of In Situ‐Generated Dienes from Isochromane‐3,4‐Diones with Nitroalkenes

Advanced Synthesis &Catalysis, Volume 367, Issue 18, September 29, 2025.
Herein, the first asymmetric [4+2] cycloaddition is reported, utilizing in situ‐generated dienes from isochromane‐3,4‐diones and nitroalkenes, catalyzed by a bifunctional thiourea organocatalyst and Brønsted base cocatalysts, yielding highly enantioselective bridged and spiro lactones, with further investigations into novel reactivity and product ...
Mohammad Sadeq Mousavi, Consiglia Tedesco, Antonio Massa   +2 more
wiley   +1 more source

Catalytic and conductivity studies in two dimensional coordination polymers built with a thiazole based ligand [PDF]

, 2018
The employment of the commercial availiable organic ligand 2-mercapto-4-methyl-5-thiazoleacetic acid (H2L) in Zn and Cd chemistry yields two-dimensional (2D) coordation polymers (CPs) with pseudopolymorphic character.
Abbasi, Baniodeh, Blatov, Brines, Chandra, Dokorou, Dolomanov, Farrugia, Finger, Grozema, Hamid, Hapka, Kannan, Kannan, Kannan, Kumar, Kumar, Ma, Ma, Maayan, Macrae, Mensforth, Moeno, Monfared, Mori, Morrison, Saeki, Sheldrick, Sheldrick, Shibahara, Siegelman, Spek, Su, Tannai, Tzeng, Ustamehmetoğlu, Vasimalai, Vicente, Zhang, Zhang   +39 more
core   +1 more source

Activation of 1,2- and 1,3-Ketoamides with Thiourea Organocatalyst for the Enantioselective Domino Synthesis of Fuctionalized Cyclohexanes

, 2013
International audienceSeveral reactive sites of 1,2- and 1,3-ketoamides were successively exploited in two complementary domino transformations for the synthesis of polysubstituted monocyclic or bridged bicyclic cyclohexanes, with the creation of up to ...
Bonne, Damien, Bugaut, Xavier, Constantieux, Thierry, Goudedranche, Sébastien, Quintard, Adrien, Raimondi, Wilfried, Rodriguez, Jean, Sanchez Duque, Maria Del Mar   +7 more
core   +4 more sources

Chiral benzimidazoles as hydrogen bonding organocatalysts [PDF]

, 2015
Several bifunctional organocatalysts bearing the benzimidazole unit have been designed in order to act as bifunctional systems by hydrogen bonding. Chiral 2-aminobenzimidazoles are conformational rigid guanidines able to catalyze enantioselectively ...
Nájera, Carmen, Yus, Miguel
core   +2 more sources

1,3-Dicarbonyl compounds in stereoselective domino and multicomponent reactions

, 2010
International audienceModern organic synthesis focuses on the discovery and the development of stereoselective multiple bond-forming transformations allowing the creation of several covalent bonds in a single operation.
Bonne, Damien, Constantieux, Thierry, Coquerel, Yoann, Rodriguez, Jean   +3 more
core   +4 more sources

Enantioselective conjugate addition of ketones to β-nitrostyrenes catalyzed by 1,2-amino alcohol-derived prolinamides [PDF]

, 2006
Various l-prolinamides 14, prepared from l-proline and chiral β-amino alcohols, are active bifunctional catalysts for the direct nitro-Michael addition of ketones to β-nitrostyrenes.
Almasi, Diana, Alonso, Diego A., Nájera, Carmen   +2 more
core   +1 more source