Results 71 to 80 of about 4,572 (262)

Stereodivergent Access to Aliphatic Nitro Compounds Bearing Multi‐Contiguous Stereocenters via Sequential Catalysis

Advanced Science, Volume 13, Issue 14, 9 March 2026.
Herein, we report a highly efficient synthesis of aliphatic nitro compounds bearing multi‐contiguous stereocenters in good yields with excellent diastereo‐ and enantio‐selectivities by combining copper‐catalyzed asymmetric conjugate addition of dialkylzinc reagents to nitroalkenes with iridium‐catalyzed asymmetric allylic substitution reaction ...
Jia‐Hao Xie, Yi‐Ming Hou, Zhi‐Jie Wu, Chao Zheng, Shu‐Li You   +4 more
wiley   +1 more source

Synthetic chemistry and biological activity of pentafluorosulphanyl (SF5) organic molecules [PDF]

, 2012
Acknowledgements We thank the European Commission for financial support (Industry Academia Partnerships and Pathways project “PET BRAIN”, Contract No 251482). S.A.
Altomonte, Stefano, Zanda, Matteo
core   +1 more source

Ring Formation in Sesquiterpene Synthesis: Biomimetic vs. Non‐Biomimetic Strategies

European Journal of Organic Chemistry, Volume 29, Issue 5, 7 February 2026.
A short review of cyclase enzyme‐mediated ring formation in sesquiterpene biosynthesis is presented as a prelude to six case studies examining the merits and demerits of biomimetic vs. non‐biomimetic strategies for carbocyclisation in the total synthesis of this iconic natural product class.
Bohan Lin, Chen Dai, Alan C. Spivey
wiley   +1 more source

Fatty acid nitroalkenes induce resistance to ischemic cardiac injury by modulating mitochondrial respiration at complex II

Redox Biology, 2016
Nitro-fatty acids (NO2-FA) are metabolic and inflammatory-derived electrophiles that mediate pleiotropic signaling actions. It was hypothesized that NO2-FA would impact mitochondrial redox reactions to induce tissue-protective metabolic shifts in cells ...
Jeffrey R. Koenitzer, Gustavo Bonacci, Steven R. Woodcock, Chen-Shan Chen, Nadiezhda Cantu-Medellin, Eric E. Kelley, Francisco J. Schopfer   +6 more
doaj   +1 more source

Synthesis of oxetane- and azetidine-containing spirocycles related to the 2,5-diketopiperazine framework [PDF]

, 2015
A simple two-step sequence is used to efficiently make novel spirocyclic analogues of the diketopiperazine nucleus. Conjugate addition of chiral α-amino esters to nitroalkenes, generated from oxetan-3-one or N-Boc-azetidin-3-one, followed by nitro group ...
Beadle, Jonathan D., Clarkson, Guy J., Powell, Nicola Helen, Raubo, Piotr, Shipman, Michael   +4 more
core   +1 more source

Nitrogen‐Rich, Tröger's Base‐Linked Porous Organic Polymers (POPs) as Heterogeneous Catalysts and Adsorbents of Organic Pollutants From Water

Journal of Applied Polymer Science, Volume 143, Issue 3, January 15, 2026.
Synthesized Tröger's based POPs showed great versatility in heterogeneous catalysis reactions and for pollutant adsorption. ABSTRACT Porous organic polymers are a new class of polymeric materials that combine permanent porosity, high surface area, monomer diversity, and synthetic tunability, making them highly promising candidates for application in ...
Tiago F. Machado, Saúl Vallejos, Artur J. M. Valente, M. Elisa Silva Serra, Dina Murtinho   +4 more
wiley   +1 more source

A Comprehensive Study of the Synthesis, Spectral Characteristics, Quantum–Chemical Molecular Electron Density Theory, and In Silico Future Perspective of Novel CBr₃-Functionalyzed Nitro-2-Isoxazolines Obtained via (3 + 2) Cycloaddition of (E)-3,3,3-Tribromo-1-Nitroprop-1-ene

Molecules
The search for new heterocyclic compounds with biological potential is one of the current challenges in modern chemistry. Therefore, the comprehensive study of (3 + 2) cycloaddition (32CA) reactions between a series of aryl-substituted nitrile N-oxides ...
Karolina Zawadzińska-Wrochniak, Karolina Kula, Mar Ríos-Gutiérrez, Bartłomiej Gostyński, Tomasz Krawczyk, Radomir Jasiński   +5 more
doaj   +1 more source

A broadened scope for the use of hydrazones as neutral nucleophiles in the presence of H-bonding organocatalysts [PDF]

, 2006
Using thioureas as H-bonding organocatalysts, nitroalkenes can be activated for the conjugate addition of hydrazones as neutral nucleophiles. Formaldehyde derivatives react at the azomethine carbon as expected, whereas hydrazones from enolizable ...
Bernardi, Luca, Fernández Fernández, Rosario Fátima, Fini, Franscesco, Lassaletta Simón, José María, Perez Herrera, Raquel, Pettersen, Daniel, Ricci, Alfredo, Sgarzani, Valentina   +7 more
core   +1 more source

Asymmetric 1,3-Dipolar Cycloadditons of Stabilized Azomethine Ylides with Nitroalkenes [PDF]

, 2014
This review highlights the biological importance of many polysubstituted nitro-prolines and -pyrrolidines. Their preparation using asymmetric 1,3-dipolar cycloadditions of azomethine ylides with nitroalkenes using diastereoselective and enantioselective ...
Nájera, Carmen, Sansano, Jose M.
core   +2 more sources

Nitration of GlcCer and Related Complex Lipids Enhances CD1d Binding Affinity and Modulates Immune Responses via Lipid Antigen Presentation to Natural Killer T Cells

ChemistryEurope, Volume 4, Issue 1, January 2026.
Nitration of glycolipids and phospholipids increases their binding to CD1d. Nitrated β‐GlcCer and phospholipids show strong CD1d binding but induce minimal cytokine production, suggesting potential immune suppression. In contrast, nitrated endogenous‐type α‐GalCer enhances cytokine responses, indicating that nitrated lipids can modulate CD1d‐mediated ...
Kodai Sueyoshi, Nanako Kawate‐Horiuchi, Kazunari Ueki, Risa Nozawa, Takanori Matsumaru, Yukari Fujimoto   +5 more
wiley   +1 more source