Results 61 to 70 of about 4,572 (262)
C=N-containing azaarenes as activating groups in enantioselective catalysis [PDF]
, 2013 Nitrogen-containing aromatic heterocycles (azaarenes) are of widespread chemical significance, and chi-ral compounds containing azaarenes feature prominently in pharmaceuticals, agrochemicals, and natural products.
Best, Daniel, Lam, Hon Wai
core +2 more sources
Substrate Walking for Selective Ene Reduction
ChemCatChem, Volume 18, Issue 9, 14 May 2026.Ene‐reductases (EREDs) efficiently reduce activated C═C bonds. Expanding the current application, they catalyze the selective reduction of highly substituted cyclohexenones. Immobilized, they were scaled to 200 mL, achieving full substrate conversion without enzyme degradation. ABSTRACT Ene‐reductases (EREDs) efficiently reduce activated C═C bonds, but
Hugo Brasselet +8 more
wiley +1 more source
Fully Selective Synthesis of Spirocyclic-1,2-oxazine N-Oxides via Non-Catalysed Hetero Diels-Alder Reactions with the Participation of Cyanofunctionalysed Conjugated Nitroalkenes [PDF]
, 2023 Przemysław Woliński +5 more
openalex +1 more source
Amino-Catalyzed Reactions of Aldehydes with Chiral Nitroalkenes
Organic Letters, 2021 Chiral nitroalkenes are used for the first time in Michael additions of aldehydes, catalyzed by pyrrolidine derivatives. They yield the same major stereoisomer with either (S)-proline or (R)-proline, but this asymmetric induction does not overcome the effect of sterically more congested catalysts.
Víctor Cascales +4 more
openaire +3 more sources
European Journal of Organic Chemistry, Volume 29, Issue 16, 25 April 2026.A chemoenzymatic synthesis of (1R,2S)‐metaraminol was developed by combining gold(I)‐catalysed alkyne hydration and stereoselective biotransamination in a sequential one‐pot process. Various phenol protection strategies were considered in oxidation‐reduction sequences, providing access to enantiopure propargylic alcohols as starting materials for ...
Lorena Escot +2 more
wiley +1 more source
Beilstein Journal of Organic Chemistry, 2018 Chiral derivatives of γ-aminobutyric acid are widely used as medicines and can be obtained by organocatalytic Michael additions. We show here the stereoselective synthesis of 4-methylpregabalin stereoisomers using a Michael addition of dimethyl malonate ...
Denisa Vargová +2 more
doaj +1 more source
Chemoproteomic profiling reveals cellular targets of nitro-fatty acids
Redox Biology, 2021 Nitro-fatty acids are a class of endogenous electrophilic lipid mediators with anti-inflammatory and cytoprotective effects in a wide range of inflammatory and fibrotic disease models.
Ming-Yu Fang +8 more
doaj +1 more source
1H-Imidazol-4(5H)-ones and thiazol-4(5H)-ones as emerging pronucleophiles in asymmetric catalysis [PDF]
, 2016 Asymmetric catalysis represents a very powerful tool for the synthesis of enantiopure compounds. In this context the main focus has been directed not only to the search for new efficient chiral catalysts, but also to the development of efficient ...
Mielgo Vicente, María Antonia +1 more
core +3 more sources
Oxetanes: Recent Advances in Synthesis, Reactivity and Medicinal Chemistry [PDF]
, 2016 The 4-membered oxetane ring has been increasingly exploited for its behaviors, i.e. influence on physicochemical properties as a stable motif in medicinal chemistry, and propensity to undergo ring opening reactions as a synthetic intermediate.
Bull, JA +4 more
core +1 more source
Organo-photocatalytic Synthesis of Functionalized Pyrroles from 2H-Azirines and α-Substituted Nitroalkenes [PDF]
, 2022 Namrata Rastogi +3 more
openalex +1 more source