Results 81 to 90 of about 3,335 (198)

Protective Effects of Nitrated Fatty Acids from Olive Oil on Cardiovascular Risk in Non-Alcoholic Fatty Liver Disease

Agrociencia Uruguay
Non-alcoholic fatty liver disease (NAFLD) is defined by the deposition of fat in the liver without alcohol consumption. Moreover, it is the most prevalent chronic liver disease worldwide and is associated with an increased risk of cardiovascular disease.
Beatriz Sánchez-Calvo, Adriana Cassina, Homero Rubbo, Andrés Trostchansky   +3 more
doaj   +1 more source

Characterization and quantification of endogenous fatty acid nitroalkene metabolites in human urine[S]

Journal of Lipid Research, 2013
The oxidation and nitration of unsaturated fatty acids transforms cell membrane and lipoprotein constituents into mediators that regulate signal transduction.
Sonia R. Salvatore, Dario A. Vitturi, Paul R.S. Baker, Gustavo Bonacci, Jeffrey R. Koenitzer, Steven R. Woodcock, Bruce A. Freeman, Francisco J. Schopfer   +7 more
doaj   +1 more source

A Greener, Efficient Approach to Michael Addition of Barbituric Acid to Nitroalkene in Aqueous Diethylamine Medium

Molecules, 2014
An efficient method for the synthesis of a variety of pyrimidine derivatives 3a–t by reaction of barbituric acids 1a,b as Michael donor with nitroalkenes 2a–k as Michael acceptor using an aqueous medium and diethylamine is described.
Hany J. Al-Najjar, Assem Barakat, Abdullah M. Al-Majid, Yahia N. Mabkhot, Manuel Weber, Hazem A. Ghabbour, Hoong-Kun Fun   +6 more
doaj   +1 more source

Synthesis, X-ray Diffraction, Thermogravimetric and DFT Analyses of Pyrimidine Derivatives

Molecules, 2014
An eco-benign synthesis of pyrimidine derivatives 2a,b containing different functional groups with different electronic character starting from nitroalkenes 1a and 2b has been described.
Assem Barakat, Hany J. Al-Najjar, Abdullah M. Al-Majid, Syed F. Adil, Mohamed Ali, Vijay H. Masand, Hazem A Ghabbour, Hoong-Kun Fun   +7 more
doaj   +1 more source

Cycloaddition Reactions of Chiral 2-Amino-1,3-butadienes with Nitroalkenes:  Synthesis of Enantiomerically Pure 4-Nitrocyclohexanones¹

, 2016
2-Amino-1,3-butadienes bearing commercially available S-(+)-2-(methoxymethyl)pyrrolidine as chiral auxiliary undergo a [4 + 2] cycloaddition reaction with nitroalkenes to furnish 4-nitrocyclohexanones upon hydrolysis of the resulting enamine.
Fernando Aznar (2087200), Cristina Ribas (3040539), José Barluenga (268140), Carlos Valdés (2473141)   +3 more
core   +1 more source

Part I: Nitroalkenes in the synthesis of heterocyclic compounds

, 2014
The applications of nitroalkenes in the synthesis of three- to five-membered O, N and S-heterocycles, including natural products are investigated in this review.
Halimehjani, Azim Ziyaei, Hooshmand, Seyyed Emad, Namboothiri, Irishi N. N.   +2 more
core   +1 more source

Direct Asymmetric Michael Addition to Nitroalkenes: Vinylogous Nucleophilicity under Dinuclear Zinc Catalysis

, 2016
Direct Asymmetric Michael Addition to Nitroalkenes: Vinylogous Nucleophilicity under Dinuclear Zinc ...
Barry M. Trost (1309395), Julien Hitce (2381818)   +1 more
core   +2 more sources

Imidazoline‐Proline and Imidazoline‐Prolinate Ligands for Copper‐Catalyzed Asymmetric Exo‐Selective [3 + 2] Cycloaddition of Iminoesters with Nitroalkenes

ChemistryEurope
Diphenylethylenediamine‐derived imidazoline‐amino acid derivatives are designed as nonphosphine chiral nitrogen ligands for metal‐catalyzed exo‐selective [3 + 2] cycloaddition reaction of iminoesters with nitroalkenes.
Yan Yu, Takuya Shimada, Chihiro Tokumitsu, Ayaka Fujiwara, Takayoshi Arai   +4 more
doaj   +1 more source

Efficient Cu-Catalyzed Asymmetric Conjugate Additions of Alkylzinc Reagents to Aromatic and Aliphatic Acyclic Nitroalkenes

, 2016
An efficient and highly enantioselective (up to 95% ee) Cu-catalyzed method for asymmetric conjugate addition (ACA) of alkylzinc reagents to acyclic disubstituted nitroalkenes is presented.
Amir H. Hoveyda (1306548), Dawn M. Mampreian (2687125)   +1 more
core   +1 more source

A new approach to the synthesis of (±)-methyl jasmonate and (±)-baclofen via conjugated addition of oxazoline cyanocuprate to Michael acceptors

Journal of the Brazilian Chemical Society, 2001
Introduction of a synthon equivalent to a carboxymethyl anion to enones and nitroalkenes, through a 1,4-addition reaction of 2,4,4-trimethyl-2-oxazoline cyanocuprate 3, proved to be an interesting methodology for the synthesis of natural products such as
Santos Alcindo A. dos, Clososki Giuliano C., Simonelli Fabio, Oliveira Alfredo R. M. de, Marques Francisco de A., Zarbin Paulo H. G.   +5 more
doaj