Results 81 to 90 of about 3,217 (192)

A new approach to the synthesis of (±)-methyl jasmonate and (±)-baclofen via conjugated addition of oxazoline cyanocuprate to Michael acceptors

Journal of the Brazilian Chemical Society, 2001
Introduction of a synthon equivalent to a carboxymethyl anion to enones and nitroalkenes, through a 1,4-addition reaction of 2,4,4-trimethyl-2-oxazoline cyanocuprate 3, proved to be an interesting methodology for the synthesis of natural products such as
Santos Alcindo A. dos, Clososki Giuliano C., Simonelli Fabio, Oliveira Alfredo R. M. de, Marques Francisco de A., Zarbin Paulo H. G.   +5 more
doaj  

Assembly of fully substituted triazolochromenes via a novel multicomponent reaction or mechanochemical synthesis

Beilstein Journal of Organic Chemistry, 2018
A new metal-free one-pot three-component procedure towards fully substituted triazolochromenes has been developed, starting from commercially available materials. Salicylaldehydes and nitroalkenes were reacted under solvent-free conditions, followed by a
Robby Vroemans, Yenthel Verhaegen, My Tran Thi Dieu, Wim Dehaen   +3 more
doaj   +1 more source

Highly efficient hydrazination of conjugated nitroalkenes via imidazole or DMAP mediated Morita-Baylis-Hillman reaction

, 2006
Novel alpha-hydrazino-alpha,beta-unsaturated nitroalkenes, which exhibit dynamic phenomenon on the NMR time scale,were synthesized in excellent yields via imidazole or DMAP mediated Morita–Baylis–Hillman (MBH) type reaction of nitroalkenes with ...
SHAIKH, MOBIN M, DADWAL, MAMTA, NAMBOOTHIRI, IRISHI NN, Namboothiri, Irishi N. N., Mobin, Shaikh M.   +4 more
core   +1 more source

Betaketothioesters in organocatalysis: Harnessing nucleophilic reactivity, the fluorophobic effect, and expanding the substrate repertoire

Tetrahedron Chem
The use of thioesters as nucleophiles marks a considerable change in organic synthesis. This new method, propelled by gentle enolization with minimal catalyst loading, results in enantiomeric excesses surpassing 95 % under ambient conditions ...
Maciej Dajek, Mikołaj J. Janicki, Paulina D. Kubiak, Julia Bąkowicz, Błażej Dziuk, Rafał Kowalczyk   +5 more
doaj   +1 more source

Nitro-fatty acid signaling: Therapeutic potential in inflammatory diseases

Redox Biochemistry and Chemistry
This review explores the interaction between nitric oxide-derived reactive species and unsaturated fatty acids, leading to the formation of electrophilic nitroalkenes, named nitro-fatty acids (NO2-FA).
Homero Rubbo, Andrés Trostchansky
doaj   +1 more source

Solvent-free organocatalytic Mukaiyama-Michael addition of 2-trimethylsilyloxy furan to nitroalkenes catalyzed by Brønsted acids

, 2009
The first organocatalytic Mukaiyama-Michael addition of 2-trimethylsilyloxy furan to nitroalkenes was promoted by Brønsted acids under solvent-free conditions.
De Sio V., Scettri A., Villano R., Acocella M. R.   +3 more
core   +1 more source

Enantioselective 1,4-Addition Reactions of Diphenyl Phosphite to Nitroalkenes Catalyzed by an Axially Chiral Guanidine

, 2016
A highly enantioselective 1,4-addition reaction of nitroalkenes with diphenyl phosphite was successfully accomplished using a newly developed axially chiral guainidine catalyst.
Hitoshi Ube (1868782), Takashi Ikehara (2467015), Masahiro Terada (153057)   +2 more
core   +1 more source

Pulmonary immunomodulation by nitroalkenes: implications for asthma-associated inflammation 2267798

Introduction Allergic asthma remains a global health concern, due to its increasing prevalence and limited treatment options. This highlights the urgent need for new mechanistic understanding and alternative therapeutic approaches. In
Sri Ramya Donepudi, Stacy Gelhaus, Ipsita Dey, Shannon Heinig   +3 more
core   +1 more source

Recognition of a Conserved Minimal Catalaphile Explains Catalyst Generality in Enantioselective Nitroalkene Reductions. [PDF]

ACS Catal
Deng Z, Jan JEL, Padalino MA, Dekeyser R, Dudding T, Johnston JN.   +5 more
europepmc   +1 more source

Synthesis of Chiral Spiro-2-pyrrolidinones with Anti-Inflammatory Properties. [PDF]

ACS Omega
Torres-Muñoz KD, Cruz-Aguilar DA, Nieto-Camacho A, Hernández-Rodríguez M.   +3 more
europepmc   +1 more source