Results 121 to 130 of about 15,048 (225)

The mechanism of action of new 5-nitroimidazole drugs which are effective against metronidazole-resistant Giardia

We have discovered new 5-nitroimidazole drugs which can overcome giardial resistance to metronidazole, the most prescribed 5-nitroimidazole drug to treat giardiasis.

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Enhancement of the antitrichomonal activity of 5-nitroimidazole derivatives by hydrogen peroxide

, 1993
The in vitro sensitivity of nine Trichomonas vaginalis isolates to commonly employed 5-nitroimidazoles (metronidazole, nimorazole, ornidazole and tinidazole) was evaluated in absence and in presence of sub-inhibitory concentrations of hydrogen peroxide ...
V. PICCI, MATTANA, Antonella, F. FRANCONI, JULIANO, Claudia Clelia Assunta, P. CAPPUCCINELLI   +4 more
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Amebiasis as a neglected tropical disease: Current knowledge gaps and future directions. [PDF]

PLoS Negl Trop Dis
Shirley DA, Jayarathne S, Warren CA, Moonah S.   +3 more
europepmc   +1 more source

Two-step distance tuning of T₁-T₂ dual-activated magnetic resonance nanoprobe for enhanced tumor diagnosis. [PDF]

Mater Today Bio
He Y, Ni N, Zhang M, Wang Y, Yang H, Ren K, Wang Y, Gao Q, Du M, Sun X, Sun H.   +10 more
europepmc   +1 more source

The influence of in vitro, nitroimidazole resistance on the efficacy of nitroimidazole-containing anti-Helicobacter pylori regimens:A meta-analysis

, 1999
OBJECTIVE: The aim of this study was to determine the influence of nitroimidazole resistance (NIR) on the efficacy of treatment for Helicobacter pylori (H.
Sluiter, WJ, van der Wouden, EJ, Kleibeuker, JH, van Zwet, AA, Thijs, JC   +4 more
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Metronidazole and ether derivatives target Helicobacter pylori via simultaneous stress induction and inhibition. [PDF]

Nat Microbiol
Fiedler MK, Pandler MSI, Gong R, Fuchs S, Rox K, Friedrich V, Pfeiffer D, Singh D, Reinhardt T, Mibus C, Huber M, Hess CR, Mejías-Luque R, Gerhard M, Groll M, Sieber SA.   +15 more
europepmc   +1 more source

Novel, Achiral 4‑Nitroimidazole Compounds with Potent Antitubercular Activity. [PDF]

ACS Omega
Matlala TB, Dube PS, Jordaan A, Legoabe LJ, Warner DF, Beteck RM.   +5 more
europepmc   +1 more source

Contribution to the Chemotherapy of Human Trypanosomiasis: Design, Synthesis, and Biological Evaluation of Dimeric 2‑Nitroimidazoles against <i>Trypanosoma cruzi</i> Amastigotes and Bloodstream <i>Trypanosoma brucei</i>. [PDF]

ACS Omega
Velez ASMM, Chaves OA, Serpa C, Salem FM, Li B, Su B, Freire-de-Lima CG, Decote-Ricardo D, Freire de Lima ME.   +8 more
europepmc   +1 more source

Synthesis and Antitrypanosomal Activity of Novel 2‑Nitroimidazole-3,5-Disubstituted Isoxazole Derivatives with Diaryl Ether and Thioether Substituents. [PDF]

ACS Omega
Santos LBB, Carvalho DB, Shiguemoto CYK, Lacerda OD, Silva TS, Portapilla GB, Silva-Filho SE, Guerrero PG, de Albuquerque S, Baroni ACM.   +9 more
europepmc   +1 more source

Refining <i>Trichomonas vaginalis</i> treatment in women and men: protocol for an open-label randomised comparison of multi-dose oral metronidazole versus single-dose oral secnidazole. [PDF]

BMJ Open
Muzny CA, Lillis RA, Chavoustie SE, Arbuckle JL, Van Gerwen OT, Sagoe M, Kandregula AR, Srivastav S, Kissinger PJ.   +8 more
europepmc   +1 more source