Results 31 to 40 of about 15,048 (225)

Molecularly Engineered Wing‐Shaped Azobenzene Memristors for Logic‐in‐Memory and Edge Visual Intelligence

Advanced Science, EarlyView.
Rational engineering of terminal substituents in symmetric azobenzene‐based molecules enables precise control over conformationally coupled charge‐transfer processes. This design yields tunable nonvolatile resistive memory behaviors, ranging from write‐once‐read‐many‐times (WORM) to rewritable switching.
Yanze Liu, Tao Han, Jiahui Ding, Hong Lian, Lingling Yao, Zhaoxin Xu, Xingyu Zhang, Shuanglong Wang, Jiangnan Xia, Tianchi Zhang, Weiwei Kang, Qingchen Dong   +11 more
wiley   +1 more source

Communication: "Position" does matter: the photofragmentation of the nitroimidazole isomers [PDF]

, 2016
A combined experimental and theoretical approach has been used to disentangle the fundamental mechanisms of the fragmentation of the three isomers of nitroimidazole induced by vacuum ultra-violet (VUV) radiation, namely, 4-, 5-, and 2-nitroimidazole. The
CARTONI, Antonella, Prince, K. C, B.P. Marinković, Marinković, B. P, Tošić, S, A. Cartoni, Chiarinelli, J, Markus, P, Bolognesi, P, P. Markus, A. R. Casavola, J. Chiarinelli, R. Richter, L. Avaldi, Borocci, S, S. Tošić, K.C. Prince, Sa'Adeh, H, Masič, M, Casavola, A. R, Richter, R, H. Sa’adeh, P. Bolognesi, S. Borocci, M. Masič, Avaldi, L.   +25 more
core   +1 more source

Recent Advances of 68Ga-Labeled PET Radiotracers with Nitroimidazole in the Diagnosis of Hypoxia Tumors

, 2023
Positron emission tomography (PET) is a noninvasive molecular imaging method extensively applied in the detection and treatment of various diseases. Hypoxia is a common phenomenon found in most solid tumors.
Anh Thu Nguyen, Hee-Kwon Kim
core   +1 more source

The Structure and Activity of Double-Nitroimidazoles. A Mini-Review

Scientia Pharmaceutica, 2018
Many interesting applications have been found for nitroimidazoles as therapeutic agents. Among others, some of these compounds can radiosensitize hypoxic tumor cells.
Justyna Żwawiak, Lucjusz Zaprutko
doaj   +1 more source

68Ga‐nitroimidazole PET/CT imaging of hypoxia in tuberculosis: A case series

Journal of Medical Radiation Sciences, 2022
Tuberculosis (TB) lesions in humans have been proven to be severely hypoxic with hypoxia leading to latency and dormancy of disease. Dormant TB lesions become less susceptible to standard TB treatment regimens with varying responses to treatment but may ...
Philippa L Bresser, Janet Reed, Mike M Sathekge, Mariza Vorster   +3 more
doaj   +1 more source

Nanomicelles for GLUT1-targeting hepatocellular carcinoma therapy based on NADPH depletion

Drug Delivery, 2023
Hepatocellular carcinoma (HCC) is a malignant tumor leading cancer-associated high mortality worldwide. Unfortunately, the most commonly used drug therapeutics not only lack of target ability and efficiency, but also exhibit severe systemic toxicity to ...
Congyi Zhang, Zehui Liu, Feng Wang, Bin Zhang, Xirui Zhang, Peiwen Guo, Tianwei Li, Sheng Tai, Changmei Zhang   +8 more
doaj   +1 more source

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

2-(3-Bromophenyl)imidazo[2,1-b]oxazole

Molbank, 2023
The microwave-assisted reaction of 2-nitroimidazole with 3-bromophenacyl bromide in the presence of potassium carbonate as a base and dimethylformamide as a solvent afforded 2-(3-bromophenyl)imidazo[2,1-b]oxazole.
Ángel Cores, Mercedes Villacampa, J. Carlos Menéndez   +2 more
doaj   +1 more source

Advancing design strategies in smart stimulus‐responsive liposomes for drug release and nanomedicine

BMEMat, EarlyView.
Schematic illustration of stimulus‐responsive liposomes designed for controlled drug release and nanomedicine. The innermost circle represents different liposomal structures, including unilamellar, multilamellar, and multivesicular liposomes. The middle layer illustrates the responsive phospholipid components.
Yuchen Guo, Nan Li, Daiwei Zhang, Jingya Gu, Zhihuan Liao, Zihao Teng, Xiangfu Du, Peter S. Timashev, Shipeng Chen, Shuaidong Huo   +9 more
wiley   +1 more source

2‐Nitroimidazole Based PET Tracers: Development of a General Synthetic Approach and Fluorination Methodology

, 2023
2-Nitroimidazole based PET tracers are widely used for non-invasive hypoxic tumor diagnosis. In this context, we report here a general method based on a central Mitsunobu reaction to easily access 2-nitroimidazole precursors. Optimization of fluorination
Vincent, Stéphane, Vincent Tadino, Xavier Maes, Nicolas Maindron, Tadino, Vincent, Rzeigui, Maha, Kévin Renault, Maindron, Nicolas, Joyard, Yoann, Maha Rzeigui, Stéphane Vincent, Horion, Romain, Renault, Kévin, Romain Horion, Maes, Xavier, Yoann Joyard   +15 more
core   +1 more source