Results 61 to 70 of about 19,627 (213)

GBM radiosensitizers: dead in the water…or just the beginning? [PDF]

, 2017
The finding that most GBMs recur either near or within the primary site after radiotherapy has fueled great interest in the development of radiosensitizers to enhance local control.
Bindra, Ranjit S., Chalmers, Anthony J., Dewhirst, Mark, Evans, Sydney   +3 more
core   +1 more source

Synthesis of Hybrid Molecules with Imidazole-1,3,4-thiadiazole Core and Evaluation of Biological Activity on Trypanosoma cruzi and Leishmania donovani

Molecules
The aim of this work was to obtain and evaluate, as antiprotozoals, new derivatives of benzoate imidazo-1,3,4-thiadiazole 18–23 based on the concepts of molecular repositioning and hybridization.
Ali Mijoba, Nereida Parra-Giménez, Esteban Fernandez-Moreira, Hegira Ramírez, Xenón Serrano, Zuleima Blanco, Sandra Espinosa, Jaime E. Charris   +7 more
doaj   +1 more source

Helicobacter pylori eradication therapy to prevent gastric cancer in healthy asymptomatic infected individuals: systematic review and meta-analysis of randomised controlled trials [PDF]

, 2014
OBJECTIVES: To determine whether searching for Helicobacter pylori and treating with eradication therapy leads to a reduction in incidence of gastric cancer among healthy asymptomatic infected individuals.
Ford, AC, Forman, D, Hunt, RH, Moayyedi, P, Yuan, Y   +4 more
core   +2 more sources

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source

Determination of antibiotics in bean sprouts by UHPLC-MS/ MS-internal standard method

Shanghai yufang yixue
ObjectiveTo establish an ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS)-internal standard method for the simultaneous determination of 59 antibiotics, including quinolones, sulfonamides, tetracyclines, macrolides and ...
ZHANG Xiaoyi, ZHENG Sanyan, ZHANG Xiuyao, LI Ruifen, YANG Shuran   +4 more
doaj   +1 more source

Simultaneous Determination of Nitroimidazoles and Quinolones in Honey by Modified QuEChERS and LC-MS/MS Analysis

International Journal of Analytical Chemistry, 2018
This study reports an analytical method for the determination of nitroimidazole and quinolones in honey using liquid chromatography-tandem mass spectrometry (LC-MS/MS).
Haiyan Lei, Jianbo Guo, Zhuo Lv, Xiaohong Zhu, Xiaofeng Xue, Liming Wu, Wei Cao   +6 more
doaj   +1 more source

Novel and emerging antimicrobial strategies in the management of oral infections

Periodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source

Preparation of 10B-enriched nitroimidazole derivative by click reaction as a functional drug for hypoxia-targeting boron-neutron capture therapy

Results in Chemistry
We report a novel drug that can be used for the treatment of tumor hypoxic cells by boron neutron capture therapy. We attempted to modify p‑boronophenylalanine, a agent for this therapy in practical use, with a hypoxia-accumulating functional group, 2 ...
Tatsuya Ozasa, Miu Mizutani, Tatsuya Nishihara, Minoru Suzuki, Kazuhito Tanabe   +4 more
doaj   +1 more source

In Vivo Evaluation of the Nitroimidazole-Based Thioflavin-T Derivatives as Cerebral Ischemia Markers

International Journal of Biomedical Imaging, 2007
Timely imaging and accurate interpretation of cerebral ischemia are required to identify patients who might benefit from more aggressive therapy, and nuclear medicine offers a noninvasive method for demonstrating cerebral ischemia.
Taiwei Chu, Zejun Li, Xinqi Liu, Xiangyun Wang   +3 more
doaj   +1 more source

Assessment and analysis of H.pylori infection treatment strategies of St. Vincent Hospital\u27s family and internal medicine clinics [PDF]

, 2019
Helicobacter pylori is a gram-negative bacteria that is responsible for causing chronic gastritis, ulcers in the stomach and intestine, and eventually even gastric lymphoma or cancer.
Orr, Rebecca
core   +1 more source