Results 71 to 80 of about 13,366 (181)

Structural insights into the enzymatic breakdown of azomycin-derived antibiotics by 2-nitroimdazole hydrolase (NnhA)

Communications Biology
The antibiotic 2-nitroimidazole (2NI) or azomycin, used for treating drug-resistant tuberculosis and imaging tumor hypoxia, requires activation by bacterial nitroreductases for its antibiotic and cytotoxic effect. Mycobacterium sp.
F. Hafna Ahmed, Jian-Wei Liu, Santana Royan, Andrew C. Warden, Lygie Esquirol, Gunjan Pandey, Janet Newman, Colin Scott, Thomas S. Peat   +8 more
doaj   +1 more source

ESTUDIO EXPERIMENTAL Y TEÓRICO DE LA SÍNTESIS DE N-ALQUIL-NITROIMIDAZOLES EXPERIMENTAL AND THEORETICAL STUDY OF SHYNTESIS OF N-ALKYL-NITROIMIDAZOLES.

Vitae, 2010
En este trabajo se realizó un estudio experimental y teórico sobre la N-alquilación de nitroimidazoles. Los N-alquil-2-metil-nitroimidazoles corresponden a moléculas con actividad biológica, que se obtienen por la reacción del 2-metil-5-nitroimidazol y ...
Constain SALAMANCA M, William TIZNADO V, Paula JARAMILLO G   +2 more
doaj  

A Lactone-Enabled Approach to Metronidazole-Based Scaffolds. [PDF]

J Org Chem
Yu X, González-Montiel GA, Shit P, Chang M, Wiest O, Mobashery S.   +5 more
europepmc   +1 more source

A New Nitroimidazole-Based Drug Attenuates Skeletal Myositis and Overcomes Benznidazole Resistance in Experimental Chagas Disease. [PDF]

ACS Pharmacol Transl Sci
Lima GDA, Gonçalves-Santos E, Benedetti MD, Silva TD, Pinheiro A, Pelinsari SM, Cunha Dos Reis LF, Gonçalves RV, Caldas IS, Franco LL, Novaes RD.   +10 more
europepmc   +1 more source

Nitroimidazoles

, 2010
openaire   +2 more sources

Exploring CPP Enhanced Hypoxia Targeting: An Approach Using Radiolabeled 2-nitroimidazole TAT Conjugate. [PDF]

Drug Dev Res
Mittal S, Jain A, Babu A, Kumar C, Mallia MB.   +4 more
europepmc   +1 more source

Epidemiology and management of nitroimidazole-refractory giardiasis. [PDF]

J Travel Med
Boté-Casamitjana A, Bodhani R, Chiodini PL, Longley N, Godbole G, Eisen S, Nabarro LE.   +6 more
europepmc   +1 more source

Crystal structure of RohS, a heme-oxygenase-like N-oxygenase from azomycin biosynthesis. [PDF]

J Biol Chem
Wei ZW, Salamon P, Higgins MA, Ryan KS.
europepmc   +1 more source

Heteroaryl Bishydrazono Nitroimidazoles: A Unique Structural Skeleton with Potent Multitargeting Antibacterial Activity. [PDF]

Int J Mol Sci
Li ZZ, Zhou CH, Liu YJ.
europepmc   +1 more source

The persistent parasite: diagnosis and treatment of resistant <i>Trichomonas vaginalis</i> infection. [PDF]

Sex Transm Infect
Young MR, Van Gerwen OT, Muzny CA.
europepmc   +1 more source