Results 61 to 70 of about 2,788 (166)

Tumor Hypoxia Imaging Agents in Nuclear Medicine

open access: yesTrends in Peptide and Protein Sciences, 2017
Hypoxia is due to imbalance in oxygen supply and oxygen demand compromising biological functions of cells. Since tumor hypoxia results in angiogenesis, apoptosis, metastasis, tumor aggressiveness and treatment failure, in vivo measurement is required ...
Mahtab Mohammadpour, Soraya Shahhosseini
doaj   +1 more source

Antimicrobial Resistance in Periodontal Disease: Rethinking Adjunctive Therapy in the Metagenomics Era, the Pressing Need for Precision Treatment and Periodontal Resistome Mapping

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 21, November 2026.
ABSTRACT Systemic antibiotics are effective when used as adjunctive therapy in the treatment of periodontitis; however, their use must be balanced against antimicrobial resistance, which is a major threat to global public health. This review provides an expert synthesis of the literature and a field‐level overview of antimicrobial resistance in ...
Meera Alghafri   +3 more
wiley   +1 more source

Nitroimidazole-Induced Reversible Neurotoxicity

open access: yesIndian Journal of Medical Specialities, 2020
The nitroimidazole group of drugs is commonly used in India and worldwide for diarrhea and other indications. People are taking it over the counter for their subsequent problems without consultation, and this is harmful to them on chronic use. Similarly,
Dinesh Chouksey   +3 more
doaj   +1 more source

Determining a Treatment Regimen With Optimal Pregnancy Outcomes in Patients With Chronic Endometritis: A Systematic Review and Network Meta‐Analysis

open access: yesHealth Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background and Aims Chronic endometritis (CE) negatively impacts pregnancy outcomes. This study aimed to compare the efficacy of various treatment regimens on pregnancy outcomes in women with CE. Methods We performed a systematic review followed by an NMA in accordance with the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses
Zheng Gong   +7 more
wiley   +1 more source

Acid‐Stable Nitrofuran Triple Therapy With Rabeprazole and Amoxicillin Targeting Helicobacter pylori Infection

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Overview: Novel nitrofuran derivatives were developed and evaluated against Helicobacter pylori to overcome antibiotic resistance and inflammation. Methods and Findings: In vitro assays using H. pylori 60190 and PMSS1 strains demonstrated potent antibacterial activity, reduced bacterial adhesion, and inhibited cytokine release from gastric epithelial ...
Nagendran Tharmalingam   +7 more
wiley   +1 more source

Simultaneous Determination of Nitroimidazoles and Quinolones in Honey by Modified QuEChERS and LC-MS/MS Analysis

open access: yesInternational Journal of Analytical Chemistry, 2018
This study reports an analytical method for the determination of nitroimidazole and quinolones in honey using liquid chromatography-tandem mass spectrometry (LC-MS/MS).
Haiyan Lei   +6 more
doaj   +1 more source

Empirical Meropenem Versus Piperacillin/Tazobactam for Critically Ill Adults With Sepsis: Feasibility of a Randomised Trial

open access: yesActa Anaesthesiologica Scandinavica, Volume 70, Issue 9, October 2026.
ABSTRACT Background Meropenem and piperacillin/tazobactam are commonly used empirical antibiotics in critically ill adults with sepsis, but whether one is superior to the other is uncertain. Methods The Empirical Meropenem versus Piperacillin/Tazobactam for Adult Patients with Sepsis (EMPRESS) trial is an ongoing investigator‐initiated, randomised ...
Nick Frørup Meier   +37 more
wiley   +1 more source

Reactions in Nitroimidazole and Methylnitroimidazole Triggered by Low-Energy (0–8 eV) Electrons

open access: yes, 2015
International audienceLow-energy electrons (0–8 eV) effectively decompose 4-nitroimidazole (4NI) and the two methylated isomers 1-methyl-5-nitroimidazole and 1-methyl-4-nitroimidazole via dissociative electron attachment (DEA).
Feketeová, Linda   +11 more
core   +1 more source

Recent Advances of 68Ga-Labeled PET Radiotracers with Nitroimidazole in the Diagnosis of Hypoxia Tumors

open access: yes, 2023
Positron emission tomography (PET) is a noninvasive molecular imaging method extensively applied in the detection and treatment of various diseases. Hypoxia is a common phenomenon found in most solid tumors.
Anh Thu Nguyen, Hee-Kwon Kim
core   +1 more source

First Experience with [18F]FAZA PET Imaging in Kidney Allograft Dysfunction

open access: yesDiagnostics
Objectives: To evaluate 18F-labelled fluoroazomycinarabinoside ([18F]F-FAZA) PET in post-transplant patients and examine the association of its kinetic and uptake parameters with kidney allograft function measurements, including laboratory and ...
Seyed Ali Mirshahvalad   +9 more
doaj   +1 more source

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