Results 81 to 90 of about 19,687 (231)

Boron Neutron Capture Therapy at a Crossroads: Translational Gap and Emerging Delivery Agents

Chemistry – A European Journal, Volume 32, Issue 17, 5 May 2026.
This review surveys recent advances in boron delivery agents for BNCT, emphasizing the shift from classical small molecules to multifunctional nanocarriers and theranostic systems. By integrating targeting, imaging, and therapy, next‐generation boron compounds aim to bridge the gap between (bio)chemical innovation and clinical translation.
Christoph Selg, Evamarie Hey‐Hawkins
wiley   +1 more source

Guidelines for the treatment of bacterial vaginosis: focus on tinidazole [PDF]

, 2009
Laura J Dickey1, Michael D Nailor2,3, Jack D Sobel41Department of Pharmacy Services, Detroit Receiving Hospital, Detroit, MI, USA; 2University of Connecticut, School of Pharmacy, Storrs, CT, USA; 3Hartford Hospital, Department of Pharmacy, Hartford, CT ...
Laura J Dickey, Michael D Nailor, Jack D Sobel   +2 more
core   +1 more source

Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA) [PDF]

, 2016
Intra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients.
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core   +4 more sources

Molecular Mechanisms of Resistance and Treatment Efficacy of Delamanid Against Mycobacterium tuberculosis: A Systematic Review

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Tuberculosis (TB) remains a major global health problem, and treatment progress is increasingly threatened by rising multidrug‐resistant tuberculosis (MDR‐TB). Delamanid (DLM), a nitroimidazole drug, has shown good efficacy and safety against both drug‐susceptible and drug‐resistant Mycobacterium tuberculosis (Mtb) strains.
Md. Mahmudul Islam, Md. Zahid Hasan, Md. Touki Tahamid Tusar, Md. Yeamin Hossain, Md. Motaher Hossain, Md. Abdulla Al Jubayed, Md. Jubaer‐Al‐Abedin, Sheikh Soikot, Shanzida Akther, Jahid Bhuyian, Hafizur Rahman Gazi, B. M. Mahmudul Hasan, Md. Shofiul Azam, Md. Enamul Haque, Abdullah‐Al‐Jubayer, Md. Faruk Hasan, F. M. Ali Haydar, Md. Khalekuzzaman, Md. Torequl Islam, Sohel Hasan   +19 more
wiley   +1 more source

Omeprazole as a Novel Treatment Option for Giardiasis in Cats

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
In this study, cats with giardiasis were allocated to omeprazole, metronidazole, secnidazole or placebo groups and monitored from day 0 to 14. Omeprazole achieved a reduction in Giardia cyst shedding comparable to metronidazole and also demonstrated faster clinical improvement, indicating a potential therapeutic advantage.
Murat Kaan Durgut, Mahmut Ok, Merve Ider, Amir Naseri, Suleyman Serhat Iyigun, Ayse Evci, Hatice Betul Sahin   +6 more
wiley   +1 more source

Bacterial vaginosis: comparative effectiveness of treatments with 5-nitroimidazole derivatives [PDF]

РМЖ. Мать и дитя, 2023
I.G. Kutsenko, I.O. Borovikov, E.I. Kravtsova, S.K. Batmen, A.S. Magay, O.I. Borovikova, V.A. Avakimyan, A.A. Andreeva Kuban State Medical University, Krasnodar, Russian Federation Aim: to perform a comparative analysis of clinical and ...
I.G. Kutsenko, I.O. Borovikov, E.I. Kravtsova, S.K. Batmen, A.S. Magay, O.I. Borovikova, V.A. Avakimyan, A.A. Andreeva   +7 more
doaj  

Methods for Improving Settlement and Metamorphosis of Shelled Marine Mollusks in Aquaculture: A Review

Aquaculture, Fish and Fisheries, Volume 6, Issue 2, April 2026.
Settlement and metamorphosis are key developmental hurdles in marine mollusk aquaculture. Environmental signals (such as biofilms, algae, and signals from conspecifics) and biochemical pathways (including nitric oxide, thyroid hormones, catecholamines, and GABA) regulate the transition of larvae into benthic juveniles. Combining ecological observations
Angelica R. Valdez, Mitchell P. Marabella, Jon‐Paul Bingham   +2 more
wiley   +1 more source

Metabolism of nitro drugs metronidazole and nitazoxanide in Giardia lamblia: characterization of a novel nitroreductase (GlNR2) [PDF]

, 2017
Objectives The protozoan parasite Giardia lamblia causes giardiasis, a persistent diarrhoea. Nitro drugs such as the nitroimidazole metronidazole and the nitrothiazolide nitazoxanide are used for the treatment of giardiasis.
Müller, Joachim, Müller, Norbert, Schildknecht, Patricia   +2 more
core  

Electrochemical behavior of indolone-N-oxides: Relationship to structure and antiplasmodial activity [PDF]

, 2012
Indolone-N-oxides exert high parasiticidal activity at the nanomolar level in vitro against Plasmodiumfalciparum, the parasite responsible for malaria.
Fabre, Paul-Louis, Ibrahim, Hany, Montrose, Armelle, Nepveu, Françoise, Nguyen, Thi Hoang Yen, Perio, Pierre, Reybier, Karine   +6 more
core   +3 more sources

Helicobacter pylori eradication therapy to prevent gastric cancer in healthy asymptomatic infected individuals: systematic review and meta-analysis of randomised controlled trials [PDF]

, 2014
OBJECTIVES: To determine whether searching for Helicobacter pylori and treating with eradication therapy leads to a reduction in incidence of gastric cancer among healthy asymptomatic infected individuals.
Ford, AC, Forman, D, Hunt, RH, Moayyedi, P, Yuan, Y   +4 more
core   +2 more sources