Results 81 to 90 of about 2,788 (166)

Efficient Synthesis of DNA Containing the Guanine Oxidation-Nitration Product 5-Guanidino-4-nitroimidazole:  Generation by a Postsynthetic Substitution Reaction

, 2016
A convertible nucleoside was synthesized and used to prepare the 2‘-deoxynucleoside of 5-guanidino-4-nitroimidazole, a putative in vivo product of the reaction of peroxynitrite with guanine.
William L. Neeley (2507212), Paul T. Henderson (847604), John M. Essigmann (357654)   +2 more
core   +1 more source

In vivo pharmacokinetic parameters in lungs for bicyclic 4-nitroimidazole analogs.

, 2014
In vivo pharmacokinetic parameters in lungs for bicyclic 4-nitroimidazole analogs.
Mahesh Nanjundappa (619075), Meera Gurumurthy (448172), Francesca Blasco (619077), Suresh B. Lakshminarayana (619070), Clifton E. Barry III (197104), Helena I. M. Boshoff (440160), Thomas Dick (284563), Joseph Cherian (619071), Anne Goh (619073), Sindhu Ravindran (619072), Amit Nayyar (619076), Ujjini H. Manjunatha (9505), Jan Jiricek (619074), Ramandeep Singh (118586), Paul C. Ho (277896)   +14 more
core   +1 more source

EXPERIMENTAL AND THEORETICAL STUDY OF SHYNTESIS OF N-ALKYL-NITROIMIDAZOLES.

Vitae, 2010
In this work we realized and experimental and theoretical study of the N-alkylation of nitroimidazoles.The N-alkyl-2-methyl-nitroimidazoles correspond to biologically active molecules, obtained by reactionof 2-methyl-5-nitroimidazole and different alkyl ...
Constain SALAMANCA M., William TIZNADO V., Paula JARAMILLO G.   +2 more
doaj  

Site selective fragmentation of halopyrimidines and nitroimidazole compounds

, 2016
Site selective fragmentation of halopyrimidines and nitroimidazole ...
Bolognesi Paola
core  

Reduction rates of F₄₂₀H₂-dependent menadione and nitroimidazole reductase activities of Ddn mutants.

, 2020
Reduction rates of F420H2-dependent menadione and nitroimidazole reductase activities of Ddn mutants.
Livnat Afriat-Jurnou (2057317), Nicholas P. West (324121), Liam K. Harold (8423295), Htin Lin Aung (6068708), Colin J. Jackson (153786), Kiel Hards (6068705), Deepak V. Almeida (8423298), Chris Greening (603810), Brendon M. Lee (8423292), Matthew C. Taylor (153774), A. Elaaf Mohamed (3367181), Eric L. Nuermberger (188446), Scott A. Beatson (6694991), Brian M. Forde (8423301), Sacha J. Pidot (7865252), F. Hafna Ahmed (3367178), Timothy P. Stinear (143097), Gregory M. Cook (7319351)   +17 more
core   +1 more source

Preparation of Nonradioactive Standards and a Precursor for a Hypoxia 18F PET Tracer Derived from 1-(β-d-Galactopyranosyl)-2-nitroimidazole

, 2017
Acetyl-protected 1-(β-d-galactopyranosyl)-2-nitroimidazole was converted to a potential precursor for a fluorine-18 labeled hypoxia tumor marker. Two nonradioactive standards, the 6′-deoxy-6′-fluorogalactosyl and the 4′-deoxy-4′-fluoroglucosyl analogue ...
Friedrich Hammerschmidt, Malová Križková, Petra, Anna Schweifer, Hammerschmidt, Friedrich; orcid:, Mereiter, Kurt, Schweifer, Anna, Petra Malová Križková, Kurt Mereiter   +7 more
core   +1 more source

Chemical structures of bicyclic 4-nitroimidazole analogs used in this study.

, 2014
Chemical structures of bicyclic 4-nitroimidazole analogs used in this study.
Mahesh Nanjundappa (619075), Meera Gurumurthy (448172), Francesca Blasco (619077), Suresh B. Lakshminarayana (619070), Clifton E. Barry III (197104), Helena I. M. Boshoff (440160), Thomas Dick (284563), Joseph Cherian (619071), Anne Goh (619073), Sindhu Ravindran (619072), Amit Nayyar (619076), Ujjini H. Manjunatha (9505), Jan Jiricek (619074), Ramandeep Singh (118586), Paul C. Ho (277896)   +14 more
core   +1 more source

“Position” does matter : the photofragmentation of the nitroimidazole isomers

, 2017
Experimental and theoretical spectroscopic methods have been combined to disentangle the fundamental mechanism of VUV induced fragmentation of the three isomers of nitroimidazole ...
Masic, M., Chiarinelli, J., Bolognesi, Paola, M.C. Castrovilli, Bolognesi, P., A. Cartoni, Castrovilli, Mattea Carmen, Sa'adeh, Hanan, Prince, K. C., Catone, Daniele, Masič, Maša, Catone, D., Chiarinelli, Jacopo, B.P. Marinkovic, Borocci, Stefano, Prince, Kevin Charles, Casavola, A., S. Tosic, J. Chiarinelli, A. Casavola, M. Masic, R. Richter, L. Avaldi, Richter, Robert, Castrovilli, M. C., D. Catone, Avaldi, Lorenzo, Richter, R., K.C. Prince, Borocci, S., Marinkovic, B. P., Casavola, Annarita, H. Sa’adeh, Tosic, S., P. Bolognesi, Marinković, Bratislav P., Sa’adeh, H., S. Borocci, Cartoni, Antonella, Cartoni, A., Tosic, Sanja D, Avaldi, L., Borocci S, Castrovilli M C, Marinkovic B P, Sa'adeh H, Prince K C, Avaldi L, Cartoni A, Richter R, Masic M, Bolognesi P, Casavola A, Catone D, Tosic S, Chiarinelli J   +55 more
core   +1 more source

Design, synthesis, reactivity, and biological activity of nitroimidazole derivatives and their copper(II) coordination compounds

Frontiers in Chemical Biology
In the last 60 years, the broad spectrum of activity of nitroimidazole derivatives against anaerobic bacteria, parasites, and protozoa has permitted their use as the first choice of treatment for many infectious diseases.
Walter Fugarolas, Lorena Reyes-Carmona, Bruno Landeros-Rivera, Argelia Almaguer-Flores, Norah Barba-Behrens   +4 more
doaj   +1 more source

Advances and prospects of nitroimidazole radiopharmaceuticals targeting tumor hypoxia

肿瘤影像学
Hypoxia, a common status of most solid tumors, is associated with tumor progression, metastasis, radiotherapy and chemotherapy resistance. Positron emission tomography (PET) and single-photon emission computed tomography (SPECT) using hypoxic-targeting ...
WANG Chengdong, DU Jin, RUAN Qing, ZHANG Junbo nbsp   +3 more
doaj