Results 71 to 80 of about 19,627 (213)

Melarsoprol cyclodextrin inclusion complexes as promising oral candidates for the treatment of human African trypanosomiasis [PDF]

open access: yes, 2011
Human African trypanosomiasis (HAT), or sleeping sickness, results from infection with the protozoan parasites <i>Trypanosoma brucei</i> (<i>T.b.</i>) <i>gambiense</i> or <i>T.b.rhodesiense</i> and is ...
AA Poltera   +45 more
core   +7 more sources

Targeting Tumor Dormancy and Recurrence: Molecular Mechanisms and Peptide Therapeutic Delivery

open access: yesMedComm – Oncology, Volume 5, Issue 1, March 2026.
This review summarizes the molecular mechanisms that regulate tumor dormancy and its role in cancer recurrence, with emphasis on immune evasion, extracellular matrix remodeling, metabolic regulation and angiogenic switching. It further discusses emerging peptide–based therapeutic strategies aimed at detecting, modulating, and eliminating dormant tumor ...
Abdur Raheem Aleem   +9 more
wiley   +1 more source

Experimental antibiotic treatment identifies potential pathogens of white band disease in the endangered Caribbean coral Acropora cervicornis [PDF]

open access: yes, 2014
Coral diseases have been increasingly reported over the past few decades and are a major contributor to coral decline worldwide. The Caribbean, in particular, has been noted as a hotspot for coral disease, and the aptly named white syndromes have caused ...
Bythell J   +5 more
core   +2 more sources

A Case of Drug‐Induced Pancreatitis

open access: yesClinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Drug‐induced pancreatitis (DIP) is a rare but important cause of acute abdominal pain, and ciprofloxacin‐associated cases are exceptionally uncommon. We report a 35‐year‐old woman with no significant medical history who developed severe epigastric pain radiating to the back, accompanied by nausea and vomiting, 3 days after initiating self ...
Muskan Shrestha   +5 more
wiley   +1 more source

Coupling of C-nitro-NH-azoles with arylboronic acids. A route to N-aryl-C-nitroazoles

open access: yesBeilstein Journal of Organic Chemistry, 2013
A method for the synthesis of N-aryl-C-nitroazoles is presented. A coupling reaction between variously substituted arylboronic acids and 3(5)-nitro-1H-pyrazole catalyzed by copper salt has been carried out in methanol in the presence of sodium hydroxide ...
Marta K. Kurpet   +5 more
doaj   +1 more source

Some nitroimidazole derivatives as antibacterial and antifungal agents in in vitro study

open access: yesJournal of Medical Science, 2019
Nitroimidazoles have wide range of therapeutic uses mainly as anaerobic antibacterials and antiprotozoal agents. Some bicyclic nitroimidazodihydrooxazoles and nitroimidazotetrahydrooxazines are found to be antituberculosis agents.
Justyna Żwawiak   +2 more
doaj   +1 more source

Ruptured Amoebic Liver Abscess With Empyema, Venous Thromboembolism and Bronchopleural Fistula: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Amoebiasis, a gastrointestinal infection caused by Entamoeba histolytica, is the third leading cause of mortality worldwide among parasitic infections with over 100,000 deaths annually. Apart from dysentery, it can manifest as extraintestinal disease, most commonly liver abscess, and rarely pulmonary, cardiac, and brain involvement.
Nur H. Ahnal   +5 more
wiley   +1 more source

A novel 3D human glioblastoma cell culture system for modeling drug and radiation responses [PDF]

open access: yes, 2016
Background. Glioblastoma (GBM) is the most common primary brain tumor, with dismal prognosis. The failure of drug–radiation combinations with promising preclinical data to translate into effective clinical treatments may relate to the use of simplified
Chalmers, Anthony   +4 more
core   +2 more sources

A Hypoxia‐Responsive Near‐Infrared Phosphorescence Nanoprobe for High‐Sensitive Detection of Tumor Cells and Imaging of Colorectal Cancer In Situ

open access: yesAggregate, Volume 7, Issue 1, January 2026.
We have successfully developed a hypoxia‐responsive near‐infrared phosphorescent probe, Ir‐PEG. This nanoprobe demonstrates high sensitivity, water solubility, and deep‐tissue penetration. It remains specifically activatable even in the hypoxic intestinal environment, facilitating high‐contrast imaging of orthotopic colon cancer.
Jian Chen   +5 more
wiley   +1 more source

Bacterial vaginosis: comparative effectiveness of treatments with 5-nitroimidazole derivatives [PDF]

open access: yesРМЖ. Мать и дитя, 2023
I.G. Kutsenko, I.O. Borovikov, E.I. Kravtsova, S.K. Batmen, A.S. Magay, O.I. Borovikova, V.A. Avakimyan, A.A. Andreeva Kuban State Medical University, Krasnodar, Russian Federation Aim: to perform a comparative analysis of clinical and ...
I.G. Kutsenko   +7 more
doaj  

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