Results 81 to 90 of about 19,627 (213)

Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA) [PDF]

, 2016
Intra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients.
A, A, A, A, A, A, A, A, A, A, A, A, A, AA, AC, AH, AJ, AK, AK, AM, AW, B, B, B, B, BJ, C, C, C, C, CA, CA, CE, D, D, D, DG, DP, E, EA, EE, F, F, F, F, FA, FM, FM, G, G, G, G, G, G, G, GA, GP, H, H, H, H, HAS, HE, I, I, I, I, IJ, J, J, JA, JE, JF, JG, JJ, JJ, JL, JR, JR, JR, JV, K, K, K, K, KA, KC, KYY, L, LJ, M, M, M, M, M, M, M, M, M, M, M, M, M, MA, MA, MA, MA, MC, MG, MM, MN, MP, N, N, NT, O, OR, P, P, P, P, PF, PK, R, R, R, R, R, R, R, RB, RG, RM, RR, RR, RS, RV, S, S, S, S, S, S, S, S, S, Sartelli, SJ, SK, SK, SM, SR, SR, SY, T, T, TL, TM, V, V, VG, VN, W, W, W, WL, WR, Y, YF, YH, YR, YS, Z, ZJ   +173 more
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Activity Profiling of Nitro‐Substituted Di(Hetero)Aryl 1,3,4‐ and 1,2,4‐Oxadiazoles: Antimicrobial, Cholinesterase Inhibition and Antioxidant Potential

Archiv der Pharmazie, Volume 359, Issue 1, January 2026.
Novel nitro‐substituted diaryl 1,3,4‐ and 1,2,4‐oxadiazoles were synthesised via molecular hybridisation of bioactive heterocycles. Selected derivatives exhibited potent antimicrobial activity, including against Mycobacterium tuberculosis and Staphylococcus aureus, and cholinesterase inhibitory activity, with promising selectivity.
Enikő Šikorová, Šárka Štěpánková, Eva Frýbová, Klára Konečná, Jana Korbielová, Markéta Švarcová, Ondřej Janďourek, Václav Pflégr, Szilvia Bősze, Martin Krátký   +9 more
wiley   +1 more source

The Impact of Chlamydia Treatment During Pregnancy on Birth Defects in New York State

Birth Defects Research, Volume 118, Issue 1, January 2026.
ABSTRACT Background Chlamydia trachomatis (CT) diagnoses are highest among females of reproductive age. Yet, little is known about adverse infant outcomes associated with treatment for CT infections during pregnancy, including birth defects. Methods Using de‐identified matched data from the New York State (NYS) Sexually Transmitted Infection ...
Elizabeth M. Boos, Meredith Howley, Tomoko Udo, Alexa Freedman, Wilson Miranda, Charles Gonzalez, Rachel Hart‐Malloy   +6 more
wiley   +1 more source

Recent Progress in the Discovery and Development of 2-Nitroimidazooxazines and 6-Nitroimidazooxazoles to Treat Tuberculosis and Neglected Tropical Diseases

Molecules, 2020
Nitroimidazole drugs have a long history as therapeutic agents to treat bacterial and parasitic diseases. The discovery in 1989 of a bicyclic nitroimidazole lead, displaying in vitro and in vivo antitubercular activity, spurred intensive exploration of ...
Hollis D. Showalter
doaj   +1 more source

The antibiotic sensitivity patterns and plasmid DNA content of gram-negative anaerobic bacteria isolated in Palmerston North, New Zealand : a thesis presented in partial fulfilment of the requirements for the degree of Masters in Science at Massey University [PDF]

, 1987
One hundred and seven Gram-negative bacteria, including 65 Bacteroides species, 28 fusobacteria and 14 veillonellae were isolated from 17 oral infections treated in two dental surgeries in Palmerston North.
Mooney, Christopher Allan
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Imaging tumour hypoxia with positron emission tomography. [PDF]

, 2014
Hypoxia, a hallmark of most solid tumours, is a negative prognostic factor due to its association with an aggressive tumour phenotype and therapeutic resistance.
A L Harris, AL Grosu, AM Jubb, B Gagel, B Gagel, B Gagel, BM Havelund, C Baldry, C West, CML Zegers, D Mönnich, D Rischin, D Thorwarth, D Thorwarth, DW Dietz, EJ Postema, F Dehdashti, F Dehdashti, F Dehdashti, F Hugonnet, F J Gilbert, GL Semenza, I N Fleming, I Shibahara, J Cheng, J Domarkas, J Overgaard, J Sato, J Yue, JA O’Donoghue, JD Chapman, JG Rajendran, JG Rajendran, JG Rajendran, JLJ Dearling, JS Lewis, JS Rasey, K J Williams, K Lehtiö, K Lehtiö, K Lehtiö, K Matsumoto, K Shi, K Tateishi, K Wang, KR Swanson, KSC Chao, L Bentzen, L Chen, L Dubois, L Li, L Vercellino, LM Cher, LS Mortensen, LS Mortensen, M Bruehlmeier, M Hu, M Höckel, M Kikuchi, M Schuetz, M Souvatzoglou, M Zimny, ME Trinkaus, MG Handley, MH Cherk, MJ Nyflot, MR Horsman, N Abolmaali, N Lee, N Takahashi, NY Lee, P Dirix, P J Blower, P McQuade, P Vaupel, P Vera, PE Valk, PW Grigsby, R Garcia–Parra, R Hueting, R Manavaki, RG Bristow, RJ Hicks, S Lord, S Okamoto, S Roels, S Thureau, SA Nehmeh, SM Eschmann, ST Lee, T Beppu, T Kaneta, T Segard, T Yamane, TG Lohith, VR Bollineni, WJ Koh, WR Wilson, X Geets, Y Minagawa   +99 more
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Performance evaluation of powdered activated carbon for removing 28 types of antibiotics from water [PDF]

, 2016
© 2016 Elsevier Ltd. Currently, the occurrence and fate of antibiotics in the aquatic environment has become a very serious problem in that they can potentially and irreversibly damage the ecosystem and human health.
Guo, W, Li, N, Ngo, HH, Wen, H, Wu, W, Zhang, X   +5 more
core   +1 more source

Bacterial vaginosis biofilms: challenges to current therapies and emerging solutions [PDF]

, 2016
Bacterial vaginosis (BV) is the most common genital tract infection in women during their reproductive years and it has been associated with serious health complications, such as preterm delivery and acquisition or transmission of several sexually ...
Abdali, Aguin, Algburi, Alves, Aroutcheva, Aroutcheva, Bahamondes, Beigi, Blackwell, Bodean, Bogavac, Bohbot, Borges, Boselli, Boskey, Boskey, Bradshaw, Braga, Brotman, Cardone, Castro, Cavera, Centers for Disease Control and Prevention, Cerca, Cerca, Chavoustie, Cole, Coste, Daniele, Dickey, Donders, Eade, Facchinetti, Falagas, Food and Agriculture Organization of the United Nations and World Health Organization, Gallo, Gardner, Gerli, Guerra, Ha, Hantoushzadeh, Holley, Hooven, Hymes, Høiby, Ison, Jacobsson, Josey, Kaewnopparat, Kaur, Koumans, Kovachev, Kovachev, Krasnopolsky, Lachapelle, Leite, Leitich, Ling, Machado, Machado, Marcone, Marrazzo, Mastromarino, McClelland, McMillan, Menard, Milani, Moffett, Mohammadzadeh, Molteni, Naidoo, Nikolov, Novakov Mikic, Núñez, Otsuki, Paavonen, Palmeira-de-Oliveira, Palmeira-de-Oliveira, Patel, Patterson, Pendharkar, Petersen, Petersen, Pirotta, Polatti, Ratzan, Ravel, Recine, Reichman, Riazi, Roberfroid, Rosen, Rossi, Rothman, Rousseau, Saunders, Schwebke, Schwebke, Schwebke, Shaaban, Simoes, Sobel, Sosto, Strandberg, Sundara Rajan, Sutyak, Sutyak, Swidsinski, Swidsinski, Swidsinski, Taheri, Tally, Thulkar, Tobudic, Togni, Trexler, Turner, Turovskiy, Turovskiy, Van Slyke, Verhelst, Verstraelen, Vicariotto, Vujic, Wewalka, Wood, Xie, Xu, Zeng, Zodzika   +129 more
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EXPERIMENTAL AND THEORETICAL STUDY OF SHYNTESIS OF N-ALKYL-NITROIMIDAZOLES.

Vitae, 2010
In this work we realized and experimental and theoretical study of the N-alkylation of nitroimidazoles.The N-alkyl-2-methyl-nitroimidazoles correspond to biologically active molecules, obtained by reactionof 2-methyl-5-nitroimidazole and different alkyl ...
Constain SALAMANCA M., William TIZNADO V., Paula JARAMILLO G.   +2 more
doaj  

Nitroreductase (GlNR1) increases susceptibility of Giardia lamblia and Escherichia coli to nitro drugs [PDF]

, 2017
Objectives The protozoan parasite Giardia lamblia causes the intestinal disease giardiasis, which may lead to acute and chronic diarrhoea in humans and various animal species.
Müller, Joachim, Müller, Norbert, Nillius, Dorothea   +2 more
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