Results 51 to 60 of about 1,162 (178)

Characterization of a CholesteroNitrone (ISQ-201), a Novel Drug Candidate for the Treatment of Ischemic Stroke

open access: yesAntioxidants, 2020
Nitrones have a well-recognized capacity as spin-traps and are considered powerful free radical scavengers, which are two important issues in hypoxia-induced oxidative stress and cell death in brain ischemia.
Emma Martínez-Alonso   +9 more
doaj   +1 more source

Mechanistic and Reactivity Insights into Diboron‐Mediated NN and NN Bond Scission

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 25, 4 July 2026.
This review highlights the emerging ability of diboron reagents to cleave both π‐bonded (N=N) and σ‐bonded (N—N) nitrogen–nitrogen linkages, integrating mechanistic understanding with recent synthetic applications. Diboron reagents have emerged as versatile reducing agents capable of transforming a broad range of functional groups through pathways like
Raúl Valderrama‐Callejón   +2 more
wiley   +1 more source

STUDY OF CYCLOREVERSION OF NTTRONE-CY CLODIMERS [PDF]

open access: yesJournal of Sciences, Islamic Republic of Iran, 1993
A series of 1,3-dipolar cycloaddition reactions are carried out using cyclodimers of simple nitrones and various dipolarophiles; substituted isoxazolidines are isolated and identified.
doaj  

Synthesis of 2‐Aza‐Bicyclo[4.3.0]nonane Derivatives Related to the Camporidines via Intramolecular [3+2]‐Cycloaddition

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 24, 23 June 2026.
The intramolecular nitrile oxide olefin [3 + 2]‐cycloaddition offers a reliable entry toward 2‐aza‐bicyclo[4.3.0]‐nonanes, a substructure found in several bioactive piperidine alkaloids. The required oxime precursors were prepared in non‐racemic form by Ir‐catalyzed asymmetric allylation and ring‐closing metathesis.
Alicia Köcher   +5 more
wiley   +1 more source

1,1‐Disubstituted Vinylbromides: Versatile Building Blocks for the Synthesis of Nitrogen‐Containing Heterocycles

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 23, 16 June 2026.
1,1‐Disubstituted vinylbromides are key intermediates for constructing nitrogen‐containing heterocycles. This review provides an overview of the synthetic applications of 1,1‐disubstituted vinylbromides and summarizes recent developments in reaction methodologies, mechanistic insights, and the structural diversity of N‐heterocyclic compounds accessible
Anne Westermeyer   +6 more
wiley   +1 more source

Electrophilic Iodination of Heterocyclic Compounds. Recent Advances 2008–2025: Part II

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 22, 9 June 2026.
Electrophilic iodination using molecular iodine and iodide sources represents an efficient approach for accessing valuable iodinated organic compounds. This review highlights recent advances in the iodination of heterocyclic compounds from 2008 to 2025, emphasizing the role of heteroaryl iodides as important synthetic intermediates for biologically ...
Njomza Ajvazi, Stojan Stavber
wiley   +1 more source

Solvent-Free 1,3-Dipolar Cycloadditions of Nitrones for a More Sustainable Synthesis of Glycomimetics

open access: yesReactions
1,3-Dipolar cycloadditions on nitrone dipoles are key reactions to access five-membered heterocycles, which are useful intermediates in the synthesis of biologically relevant glycomimetics.
Debora Pratesi   +4 more
doaj   +1 more source

BET & ELF Quantum Topological Analysis of Neutral 2-Aza-Cope Rearrangement of γ-Alkenyl Nitrones

open access: yesMolecules, 2017
The 2-Aza-Cope rearrangement of γ-alkenyl nitrones is a rare example of the neutral thermal 2-aza-Cope process that usually takes place with cationic species.
Pedro Merino   +3 more
doaj   +1 more source

Lighting the Path to Cyclic Phosphonamides via Halogen‐Bond Electron Donor–Acceptor Activation

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 11, 3 June 2026.
Cyclic phosphinamides are valuable scaffolds for optoelectronic applications, yet remain difficult to access with existing methods. Here, we highlight a mild and straightforward visible light‐driven strategy that enables the formation of cyclic phosphinamides and thiophosphinamides.
Clara Faure   +8 more
wiley   +1 more source

nitrones

open access: yes, 2014
Citation: 'nitrones' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.N04164 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

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