Results 81 to 90 of about 12,404 (251)
Clinical and Translational Medicine, Volume 15, Issue 12, December 2025.Exosomes, modified through multidimensional approaches including physical, chemical and genetic means, and equipped with brain‐targeted peptides and therapeutic agents, are capable of crossing the blood‒brain barrier for precise delivery. They can simultaneously remove amyloid‐beta plaques and neurofibrillary tangle, inhibit neuroinflammation, and pave
Yuehan Zhang +4 more
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Recent Advances in Ene Reactions with Carbon Enophiles
Advanced Synthesis &Catalysis, Volume 367, Issue 22, November 28, 2025.Recent advances in the classical intra‐ and intermolecular ene nexus with carbon enophiles (alkenes, alkynes, arynes, and allenes) show a considerable increase in structural complexity and an enormous potential for functional applications in polymer science.
Thomas J. J. Müller
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Kinugasa Reactions in Water: From Green Chemistry to Bioorthogonal Labelling
Molecules, 2015 The Kinugasa reaction has become an efficient method for the direct synthesis of β-lactams from substituted nitrones and copper(I) acetylides. In recent years, the reaction scope has been expanded to include the use of water as the solvent, and with ...
Mariya Chigrinova +4 more
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Phosphonated Carbocyclic 2'-Oxa-3'-azanucleosides as New Antiretroviral Agents [PDF]
, 2007 Phosphonated carbocyclic 2¢-oxa-3¢-azanucleosides have been synthesized and tested for their antiretroviral activity. The obtained results have shown that some of the compounds were as powerful as azydothymidine in inhibiting the reverse transcriptase ...
Balestrieri, E +10 more
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Para-Substituted α-Phenyl-N-tert-butyl Nitrones: Spin-Trapping, Redox and Neuroprotective Properties [PDF]
, 2020 Anaïs Deletraz +9 more
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, 2014 Citation: 'nitrones' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.N04164 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
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Additional outcomes and subgroup analyses of NXY-059 for acute ischemic stroke in the SAINT I trial [PDF]
, 2006 <p><b>Background and Purpose:</b> NXY-059 is a free radical-trapping neuroprotectant demonstrated to reduce disability from ischemic stroke. We conducted analyses on additional end points and sensitivity analyses to confirm our findings.
Ashwood, T. +11 more
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ChemistryEurope, Volume 3, Issue 6, November 11, 2025.The nitrone moiety's versatility in covalent organic polymer (COP) materials is shown by its ability to form either nitrone‐linked or oxime O‐ether‐linked COPs from the same building blocks, simply by changing reaction conditions. Additionally, its 1,3‐dipolar cycloaddition reactivity enabled the synthesis of a functionalized isoxazolidine‐linked ...
Beatriz de Santos +6 more
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(Z)-1-(1,3-Diphenyl-1H-pyrazol-4-yl)-N-phenylmethanimine N-oxide
IUCrData, 2018 In the title nitrone, C22H17N3O, the dihedral angles between the central pyrazole ring and pendant N-bound, C-bound and nitrone-bound phenyl rings are 20.93 (6), 41.27 (6), and 32.57 (6)°, respectively.
Shaaban K. Mohamed +5 more
doaj +1 more source
Silver and platinum-catalysed addition of O–H and N–H bonds to allenes [PDF]
, 2014 Transition-metal catalysed nucleophile addition to allenes is a very powerful tool for the synthesis of functionalised molecules containing heteroatoms, heterocycles in the intramolecular version, or allyl derivatives in the intermolecular version.
Munoz-Herranz, Maria
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