Results 171 to 180 of about 628,729 (310)

Mechanotransduction of Piezo1 in the cancer microenvironment: implications for NK cell-based immunotherapy. [PDF]

Front Oncol
Cui X, Zhang B, Zhao J, Tian H.
europepmc   +1 more source

High‐Throughput 3D Matrigel‐based Droplet Microfluidics for Single‐Cell Function‐to‐Omics Analysis of Cytotoxic Immune Cells in Solid Tumor Interactions

Advanced Materials Technologies, EarlyView.
A 3D Matrigel‐based droplet microfluidics platform that allows physiologically relevant analysis of single immune‐tumor interactions in solid tumors. By integrating real‐time functional imaging with fluorescence‐activated droplet sorting and RNA sequencing, the system links immune cytotoxic behavior to transcriptomic profiles, providing a scalable ...
Christina Sharkey, Harry Akligoh, Michael Finocchiaro, Abhishek Srihari Rampelli, Zongwei Wang, Aria F. Olumi, Tania Konry   +6 more
wiley   +1 more source

Peptide-adaptive NK cell memory in the absence of functional TCR genes. [PDF]

Immunohorizons
Bryan S, Gamage GS, Dey S, Medina-Luna D, Parsons BD, Makrigiannis AP.   +5 more
europepmc   +1 more source

Hydrogel Confinement Strategies for 3D Cell Culture in Microfluidic Systems

Advanced Materials Technologies, EarlyView.
Hydrogel confinement structures are key to organizing 3D cell cultures in microfluidic devices. This review classifies five structural strategies (micropillar, phaseguide, porous membrane, stepped‐height, and support‐free) and examines their trade‐offs alongside fabrication methods.
Soohyun Kim, Min Seok Lee, Sung Kyun Lee
wiley   +1 more source

Strategies for the Development of NK Cell-Based Therapies for Cancer Treatment. [PDF]

Cells
Budagova T, Efremova A, Maiak M, Goldshtein D.   +3 more
europepmc   +1 more source

Ductility Tuning via Cluster Network Characteristics of Porous Components

Advanced Materials Technologies, EarlyView.
Network optimization via cluster characteristics induced by interaction of stress concentration is proposed, demonstrating increased cluster size and dispersion in non‐uniform porous components. The optimized structures exhibit, for the first time, that enhanced ductility and damage progression is controllable through zigzag cluster network designed by
Ryota Toyoba, Yuichi Otsuka, Ian J Davies, Naritoshi Aoyagi, Yukio Miyashita   +4 more
wiley   +1 more source

Key regulatory roles of PRDM1 in human NK-cell differentiation and activation. [PDF]

Leukemia
Liu X, Shi Y, Zhang J, Shetty K, Chew K, Küçük C, Gong Q, Esmeray E, Li H, Chen R, Pan S, Dąbrowska K, Moore RE, Garcia-Mansfield K, Pirrotte P, Wang J, Li Y, Dong G, Lee L, McKeithan TW, Iqbal J, Chan WC.   +21 more
europepmc   +1 more source

NK cells [PDF]

Science-Business eXchange, 2010
openaire   +1 more source

Mechanistic Origin of Photodegradation and Impurity Effects in Donor–Acceptor Luminescent Radicals

Advanced Optical Materials, EarlyView.
Purification‐dependent impurities distort the apparent optical and analytical data of TTM‐based radicals without altering their intrinsic photophysical properties. Carbazole attachment elevates the activation barrier of the photodegradation pathway, offering design principles for achieving more robust luminescent radical materials.
Takuya Hosokai, Wataru Ota, Kenshiro Matsuda, Hikaru Ishii, Amane Niwa, Yasuo Nakayama, Keisuke Nakamura, Daiki Asakawa, Emiko Fujiwara, Tohru Sato, Ken Albrecht   +10 more
wiley   +1 more source

Progressive NK-cell dysfunction and ILC imbalance favor immune evasion in multiple myeloma. [PDF]

Blood Adv
Bilotta MT, Solimando AG, Desantis V, Di Marzo L, Sabatini A, Forcelloni S, Andriano A, Morizio A, Argentiero A, Ria R, Quatrini L, Moretta L, Vacca P, Tumino N.   +13 more
europepmc   +1 more source