Results 11 to 20 of about 314,994 (315)

T-Cell Immune Imbalance in Rheumatoid Arthritis Is Associated with Alterations in NK Cells and NK-Like T Cells Expressing CD38

open access: yesJournal of Innate Immunity, 2021
Background: CD38+ NK (CD3− CD16+ CD38+ CD56+) cells were increased in rheumatoid arthritis (RA), which suppressed Treg cell differentiation. This study explored how CD38+ NK cells regulated CD4+ T-cell differentiation into Treg cells in RA.
Hongxing Wang   +3 more
doaj   +1 more source

NK Cells and Psoriasis [PDF]

open access: yesBioMed Research International, 2011
Psoriasis is a chronic condition of the skin characterised by distinctive scaly plaques. The immune system is now thought to play a major role in the development and pathogenesis of psoriasis with immune cells and cytokines influencing keratinocyte function.
Dunphy, Sinéad, Gardiner, Clair M.
openaire   +4 more sources

NK and T cells constitute two major, functionally distinct intestinal epithelial lymphocyte subsets in the chicken [PDF]

open access: yes, 2001
Non-mammalian NK cells have not been characterized in detail; however, their analysis is essential for the understanding of the NK cell receptor phylogeny.
Manfred Stangassinger   +5 more
core   +1 more source

Strategies to rescue mesenchymal stem cells (MSCs) and dental pulp stem cells (DPSCs) from NK cell mediated cytotoxicity. [PDF]

open access: yesPLoS ONE, 2010
BACKGROUND: The aim of this paper is to study the function of allogeneic and autologous NK cells against Dental Pulp Stem Cells (DPSCs) and Mesenchymal Stem Cells (MSCs) and to determine the function of NK cells in a three way interaction with monocytes ...
Anahid Jewett   +7 more
doaj   +1 more source

Potentiation of natural killer cells to overcome cancer resistance to NK cell-based therapy and to enhance antibody-based immunotherapy

open access: yesFrontiers in Immunology, 2023
Natural killer (NK) cells are cellular components of the innate immune system that can recognize and suppress the proliferation of cancer cells. NK cells can eliminate cancer cells through direct lysis, by secreting perforin and granzymes, or through ...
Massimo Fantini   +2 more
doaj   +1 more source

NK cell metabolism [PDF]

open access: yesJournal of Leukocyte Biology, 2019
AbstractNatural Killer (NK) cells are important antiviral and anticancer effector cells. They have excellent potential for immunotherapy although impaired functions during cancer limit their effectiveness. The discovery that cellular metabolism can impact on and regulate immune functions has led to an explosion of articles in this new area of ...
openaire   +2 more sources

A distinct subset of human NK cells expressing HLA-DR expand in response to IL-2 and can aid immune responses to BCG. [PDF]

open access: yes, 2011
Subsets of NK cells can have distinct functions. Here, we report that >25% of human peripheral blood NK cells express HLA-DR after culture with IL-2.
Emma L. Wise   +18 more
core   +1 more source

The mechanobiology of NK cells- ‘Forcing NK to Sense’ target cells

open access: yesBiochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2023
Natural killer (NK) cells are innate immune lymphocytes that recognize and kill cancer and infected cells, which makes them unique 'off-the-shelf' candidates for a new generation of immunotherapies. Biomechanical forces in homeostasis and pathophysiology accrue additional immune regulation for NK immune responses.
Wong, Darren Chen Pei, Ding, Jeak Ling
openaire   +2 more sources

Immunorecognition of leukemic stem cells by NK cells : the role of HDAC inhibitors in NKG2D ligand-mediated anti-tumor responses in acute myeloid leukemia [PDF]

open access: yes, 2008
The diagnosis of acute myeloid leukemia (AML) is associated to a poor long-term outcome due to frequent relapse despite intensive chemotherapy, radiation and hematopoietic stem cell transplantation (HSCT) as well as continuous advances in treatment ...
Langenkamp, Ulrich
core   +1 more source

Tumor-priming converts NK cells to memory-like NK cells

open access: yesOncoImmunology, 2017
Fascinating earlier evidence suggests an intrinsic capacity of human natural killer (NK) cells to acquire adaptive immune features in the context of cytomegalovirus (CMV) infection or pro-inflammatory cytokine stimulation.
Marina Pal   +10 more
doaj   +1 more source

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