Results 11 to 20 of about 275,021 (166)
The Journal of Immunology, 2007 Abstract In this review, we overview the main features and functions of NK cells, focusing on their role in cell-mediated immune response to tumor cells. In parallel, we discuss the information available in the field of NK cell receptors and offer a wide general overview of functional aspects of cell targeting and killing, focusing on ...
Zamai, L +7 more
openaire +6 more sources
BioMed Research International, 2011 Psoriasis is a chronic condition of the skin characterised by distinctive scaly plaques. The immune system is now thought to play a major role in the development and pathogenesis of psoriasis with immune cells and cytokines influencing keratinocyte function.
Dunphy, Sinéad, Gardiner, Clair M.
openaire +4 more sources
Evidence-Based Complementary and Alternative Medicine, 2004 It is believed that tumor development, outgrowth and metastasis are under the surveillance of the immune system. Although both innate and acquired immune systems play roles, innate immunity is the spearhead against tumors. Recent studies have revealed the critical role of natural killer (NK) cells in immune surveillance and that NK cell activity is ...
Takeda, Kazuyoshi, Okumura, Ko
openaire +2 more sources
NK-B cell cross talk induces CXCR5 expression on natural killer cells
iScience, 2021 Summary: B cell follicles (BCFs) in lymph nodes (LNs) are generally exempt of CD8+ T and NK cells. African green monkeys (AGMs), a natural host of simian immunodeficiency virus (SIV), display NK cell-mediated viral control in BCF.
Philippe Rascle +10 more
doaj +1 more source
Tumor-priming converts NK cells to memory-like NK cells
OncoImmunology, 2017 Fascinating earlier evidence suggests an intrinsic capacity of human natural killer (NK) cells to acquire adaptive immune features in the context of cytomegalovirus (CMV) infection or pro-inflammatory cytokine stimulation.
Marina Pal +10 more
doaj +1 more source
Phenotypic and Functional Plasticity of CXCR6+ Peripheral Blood NK Cells
Frontiers in Immunology, 2022 Human NK cells are comprised of phenotypic subsets, whose potentially unique functions remain largely unexplored. C-X-C-motif-chemokine-receptor-6 (CXCR6)+ NK cells have been identified as phenotypically immature tissue-resident NK cells in mice and ...
Laura S. Angelo +6 more
doaj +1 more source
Journal of Leukocyte Biology, 2019 AbstractNatural Killer (NK) cells are important antiviral and anticancer effector cells. They have excellent potential for immunotherapy although impaired functions during cancer limit their effectiveness. The discovery that cellular metabolism can impact on and regulate immune functions has led to an explosion of articles in this new area of ...
openaire +2 more sources
NK cells are not required for spontaneous autoimmune diabetes in NOD mice. [PDF]
PLoS ONE, 2012 NK cells have been shown to either promote or protect from autoimmune diseases. Several studies have examined the role of receptors preferentially expressed by NK cells in the spontaneous disease of NOD mice or the direct role of NK cells in acute ...
Joshua N Beilke +5 more
doaj +1 more source
Journal of Neuroinflammation, 2019 Background Recent studies have demonstrated that natural killer (NK) cells can modulate other immune components and are involved in the development or progression of several autoimmune diseases. However, the roles and mechanisms of NK cells in regulating
Chun-Lin Yang +9 more
doaj +1 more source
A four-stage model for murine natural killer cell development in vivo
Journal of Hematology & Oncology, 2022 Natural killer (NK) cells are the predominant innate lymphoid cells that mediate anti-viral and anti-tumor immunity. NK cells arise from hematopoietic stem cells in the bone marrow (BM) and undergo lineage specification and maturation.
Shoubao Ma +2 more
doaj +1 more source