Results 81 to 90 of about 5,274 (162)

Potential Beneficial Effects of Cytomegalovirus Infection after Transplantation

Frontiers in Immunology, 2018
Cytomegalovirus (CMV) infection can cause significant complications after transplantation, but recent emerging data suggest that CMV may paradoxically also exert beneficial effects in two specific allogeneic transplant settings.
Nicolle H. R. Litjens, Lotte van der Wagen, Jurgen Kuball, Jaap Kwekkeboom   +3 more
doaj   +1 more source

SARS-CoV-2 infection induces adaptive NK cell responses by spike protein-mediated induction of HLA-E expression

Emerging Microbes and Infections
HLA-E expression plays a central role for modulation of NK cell function by interaction with inhibitory NKG2A and stimulatory NKG2C receptors on canonical and adaptive NK cells, respectively.
Mohammad Zahidul Hasan, Maren Claus, Nadine Krüger, Sarah Reusing, Eline Gall, Christina Bade-Döding, Armin Braun, Carsten Watzl, Markus Uhrberg, Lutz Walter   +9 more
doaj   +1 more source

Favorable impact of natural killer cell reconstitution on chronic graft-versus-host disease and cytomegalovirus reactivation after allogeneic hematopoietic stem cell transplantation

Haematologica, 2014
Natural killer cells are the first lymphocyte subset to reconstitute, and play a major role in early immunity after allogeneic hematopoietic stem cell transplantation.
Vissal David Kheav, Marc Busson, Catherine Scieux, Régis Peffault de Latour, Guitta Maki, Philippe Haas, Marie-Christine Mazeron, Maryvonnick Carmagnat, Emeline Masson, Aliénor Xhaard, Marie Robin, Patricia Ribaud, Nicolas Dulphy, Pascale Loiseau, Dominique Charron, Gérard Socié, Antoine Toubert, Hélène Moins-Teisserenc   +17 more
doaj   +1 more source

Late Development of FcεRγneg Adaptive Natural Killer Cells Upon Human Cytomegalovirus Reactivation in Umbilical Cord Blood Transplantation Recipients

Frontiers in Immunology, 2018
In human natural killer (NK) cells, human cytomegalovirus (HCMV) has been shown to be a driving force capable of inducing the expansion of a highly differentiated NKG2C+CD57+ subset, persisting over time in both HCMV+ healthy subjects and umbilical cord ...
Letizia Muccio, Michela Falco, Alice Bertaina, Franco Locatelli, Franco Locatelli, Francesco Frassoni, Simona Sivori, Simona Sivori, Lorenzo Moretta, Alessandro Moretta, Alessandro Moretta, Mariella Della Chiesa, Mariella Della Chiesa   +12 more
doaj   +1 more source

Expansion of a unique CD57 ⁺ NKG2C ^hi natural killer cell subset during acute human cytomegalovirus infection

, 2011
During human CMV infection, there is a preferential expansion of natural killer (NK) cells expressing the activating CD94–NKG2C receptor complex, implicating this receptor in the recognition of CMV-infected cells.
Vanessa A. York, Sandra Lopez-Vergès, Marcelo J. Pando, Jessica Jarjoura, Jeffrey P. Houchins, Phillip J. Norris, Douglas F. Nixon, Steve Miller, Sang-Mo Kang, Jeffrey M. Milush, Brian S. Schwartz, Lewis L. Lanier   +11 more
core   +1 more source

Supplementary Material for: Cytomegalovirus-Infected Primary Endothelial Cells Trigger NKG2C+ Natural Killer Cells

, 2016
Among innate cells, natural killer (NK) cells play a crucial role in the defense against cytomegalovirus (CMV). In some individuals, CMV infection induces the expansion of NKG2C+ NK cells that persist after control of the infection.
Céline Bressollette (2632042), Zakia Djaoud (2632060), Nathalie Gérard (2632051), Katia Gagne (2632048), Pierre-Jean Gavlovsky (2632057), Christelle Retière (2632054), Souad Mehlal (2632039), Béatrice Charreau (114735), Raphaëlle Riou (2632045)   +8 more
core   +1 more source

The Direct Influence of Cytomegalovirus Lysate on the Natural Killer Cell Receptor Repertoire

Iranian Journal of Allergy, Asthma and Immunology, 2021
Natural killer (NK) cells are essential for controlling certain viral infections, including cytomegalovirus (CMV). In particular, the importance of NK cells in the context of CMV infection is underscored by the adaptive capabilities of these cells ...
Saeede Soleimanian, Ramin Yaghobi, Mohammad Hossein Karimi, Bita Geramizadeh, Jamshid Roozbeh   +4 more
doaj  

Pretransplant adaptive NKG2C+ NK cells protect against cytomegalovirus infection in kidney transplant recipients

, 2019
Cytomegalovirus (CMV) infection constitutes a complication for kidney transplant recipients (KTR) and CMV-specific T cells reduce the risk of viral replication in seropositive patients.
Llinàs-Mallol, Laura, Heredia, Gemma, Pérez-Sáez, María José, Ataya Fernández, Michelle, 1993-, Pascual, Julio (Pascual Santos), Costa García, Marcel, 1989-, Raïch-Regué, Dàlia, López-Botet, M. (Miguel), Yélamos López, José, Vila, Joan, Crespo Barrio, Marta, Redondo Pachón, María Dolores, Vilches, Carlos   +12 more
core   +1 more source

Combined dendritic cell and anti-TIGIT immunotherapy potentiates adaptive NK cells against HIV-1

EMBO Molecular Medicine
Natural Killer (NK) cells are promising candidates for targeting persistently infected CD4 + T cells in people with HIV-1 (PWH). However, chronicity of HIV-1 infection impairs NK cell functionality, requiring additional strategies to potentiate their ...
Ildefonso Sánchez-Cerrillo, María Agudo-Lera, Olga Popova, Ilya Tsukalov, Marta Calvet-Mirabent, Ignacio de los Santos, Lucio García-Fraile, Patricia Fuentes, Cristina Delgado-Arévalo, Juan Alcain, Nerea Sánchez-Gaona, Judith Grau-Expósito, María Lázaro-Díez, Cecilia Muñoz-Calleja, Arantzazu Alfranca, Meritxell Genescà, Julia G Prado, Vladimir Vrbanac, Alejandro Balazs, María José Buzón, María L Toribio, María A Muñoz-Fernández, Francisco Sánchez-Madrid, Enrique Martín-Gayo   +23 more
doaj   +1 more source

Functional Anti-CD94/NKG2A and Anti-CD94/NKG2C Autoantibodies in Patients With Systemic Lupus Erythematosus

, 2015
Objective. Recently we serendipitously identified a patient with systemic lupus erythematosus (SLE) who was positive for autoantibodies to CD94/natural killer receptor group 2A (NKG2A).
Theorell, J,, Karin Hjorton, Eloranta, Maija-Leena,, Jakob Theorell, Roennblom, L, Hjorton, K, Pieter Spee, Theorell, Jakob, Niklas Hagberg, Spee, Pieter, Eloranta, M-L, Lars Rönnblom, Maija-Leena Eloranta, Yenan T. Bryceson, Hagberg, N, Hjorton, Karin,, Bryceson, YT, Bryceson, Yenan T., Hagberg, Niklas,, Rönnblom, Lars,, Spee, P   +20 more
core   +1 more source