Results 71 to 80 of about 4,280 (166)
Transplantation Direct, 2017 Background. Antibody-mediated rejection in solid organ transplantation is an important immunological barrier to successful long-term graft survival. Next to complement activation, natural killer (NK) cells have been implicated in the process.
Clive M. Michelo, PhD +5 more
doaj +1 more source
Adaptive NKG2C+ NK Cell Response and the Risk of Cytomegalovirus Infection in Kidney Transplant Recipients [PDF]
The Journal of Immunology, 2017 Abstract CMV infection in kidney transplant recipients (KTRs) has been associated with an increased risk for graft loss and reduced host survival. CMV promotes persistent expansions of NK cells expressing the CD94/NKG2C receptor. The NKG2C (KLRC2) gene is frequently deleted, and copy number influences the adaptive response of NKG2C ...
Dolores Redondo-Pachón +9 more
openaire +2 more sources
T Cell Receptor Repertoires Across the Continuum of Vascular, Myocardial, and Age‐Related Diseases
Immunological Reviews, Volume 339, Issue 1, May 2026.ABSTRACT Cardiovascular diseases (CVD) are shaped by a complex interplay with immune mechanisms. In particular, the distinct roles of antigen‐specific T cell mechanisms are emerging as critical determinants across a broad spectrum of conditions, ranging from atherosclerosis, myocardial infarction (MI), heart failure (HF), and myocarditis. Because these
Leon Richter +3 more
wiley +1 more source
Aging Cell, Volume 25, Issue 4, April 2026.Single‐cell profiling of PBMCs from centenarians, their offspring, and elderly controls revealed distinct myeloid‐to‐effector immune cell communication programs. General aging was characterized by SASP‐enriched signaling associated with immunosenescence, whereas healthy aging showed positive immune regulatory signaling associated with enhanced ...
Liwei Qiu +7 more
wiley +1 more source
VirusesHuman cytomegalovirus (CMV) is a common herpesvirus causing lifelong latent infection in most people and is a primary cause of congenital infection worldwide.
Chiara Pighi +11 more
doaj +1 more source
Haematologica, 2016 We analyzed the impact of human cytomegalovirus infection on the development of natural killer cells in 27 pediatric patients affected by hematological malignancies, who had received a HLA-haploidentical hematopoietic stem cell transplantation, depleted ...
Letizia Muccio +9 more
doaj +1 more source
HLA, Volume 107, Issue 4, April 2026.ABSTRACT Matching of HLA‐A, ‐B and ‐DRB1 is the gold standard in histocompatibility testing for kidney transplantation. A good HLA match reduces the risk of alloimmunisation, thereby decreasing the likelihood of graft failure and potentially enabling reduced immunosuppression therapy. However, the role of the non‐classical HLA and MIC genes is not well
Silja Tammi +6 more
wiley +1 more source
Antibodies, 2013 Human cytomegalovirus (HCMV) is an important pathogen that infects the majority of the population worldwide, yet, currently, there is no licensed vaccine.
Rebecca J. Aicheler +4 more
doaj +1 more source
Multiphysics‐Driven Assembly of Biomimetic Vesicles
Advanced Materials, Volume 38, Issue 13, 3 March 2026.Artificial extracellular vesicles, derived from cell membranes, are manufactured using a multiphysics‐integrated microfluidic platform that combines nanoknife membrane rupture, herringbone chaotic mixing, and acoustothermal modulation. This standardizable workflow enables the predictable control of vesicle formation and therapeutic loading, while ...
Timofei Solodko +16 more
wiley +1 more source
American Journal of Reproductive Immunology, Volume 95, Issue 3, March 2026.ABSTRACT Problem Natural killer (NK) cells are critical regulators of immune balance at the maternal–fetal interface. T‐bet (Tbx21) is a key transcription factor shaping NK cell effector functions, yet its role in decidual NK (dNK) cell adaptation across gestation remains unclear.
Mona A. Mohamed +6 more
wiley +1 more source