Results 101 to 110 of about 22,145 (200)

The Unfolded Protein Response as a Modulator of Cancer‐Immune Cell Communication in the Tumour Microenvironment

Journal of Cellular and Molecular Medicine, Volume 30, Issue 19, October 2026.
ABSTRACT The tumour microenvironment (TME) comprises a dynamic network of structural, cellular, and signalling components that interact to influence tumour development. Immune cells play a key role in recognizing and eliminating cancer cells through detection of tumour‐derived membrane and secreted proteins processed in the endoplasmic reticulum (ER ...
Yew Hwang Chee, Matthieu Moncan, Eileen Reidy, Adrienne M. Gorman, Afshin Samali   +4 more
wiley   +1 more source

The Human Soluble NKG2D Ligand Differentially Impacts Tumorigenicity and Progression in Temporal and Model-Dependent Modes

Biomedicines
NKG2D is an activating receptor expressed by all human NK cells and CD8 T cells. Harnessing the NKG2D/NKG2D ligand axis has emerged as a viable avenue for cancer immunotherapy.
Anthony V. Serritella, Pablo Saenz-Lopez Larrocha, Payal Dhar, Sizhe Liu, Milan M. Medd, Shengxian Jia, Qi Cao, Jennifer D. Wu   +7 more
doaj   +1 more source

NKG2D

AfCS-Nature Molecule Pages, 2009
openaire   +1 more source

MicroRNAs and polymorphisms influencing MICA immune modulation. [PDF]

Mol Biol Rep
Nicoletti MB, Ferraz IM, Moço AC, da Cruz Castelli E, Castro CFB.   +4 more
europepmc   +1 more source

Natural killer cell receptor signaling and activation depend on cell cycle stages. [PDF]

PLoS Comput Biol
Wethington D, Nayak I, Jensen H, Stewart WC, Aguilar OA, Chen SY, Nolan GP, Behbehani GK, Lanier LL, Das J.   +9 more
europepmc   +1 more source

Comparative profiling of MAIT cells across gastrointestinal cancers identifies conserved NK receptor dysregulation and HCC-specific defects in cytotoxicity and XBP1s signaling. [PDF]

Front Immunol
Proß V, Ruhm AH, Thole LML, Tóth L, Harikumar Parvathy G, Jäger P, Götz C, Damm G, Seehofer D, Bayerl C, Herbst H, Macke A, Frese V, Sakaki A, Hanisch-Hernandez M, Rosseck F, Treskatsch S, Friedersdorff F, Treese C, Daum S, Laue D, Ruf B, Lukassen S, Kotsch K.   +23 more
europepmc   +1 more source

Engineered CAR-T extracellular vesicles loaded with miR-17-5p inhibitor suppress hepatocellular carcinoma progression. [PDF]

Front Immunol
Zhou Z, Wu H, Zhao S, Chen M, Lin W, Li J, Zheng Q.   +6 more
europepmc   +1 more source

Epigenetic modulation of NKG2D ligands enhances NKG2D-CAR T cell efficacy in neuroblastoma. [PDF]

J Transl Med
Navarro-Zapata A, De Santisteban MO, Regojo-Zapata RM, Ibáñez-Navarro M, Clares-Villa L, de la Hoz M, Romero A, Mestre-Durán C, Al-Akioui Sanz K, Bareke H, Naharro S, Minguillón J, Pertíñez L, Riestra N, Masot M, Martín-Cortázar C, Aguirre-Portolés C, Ferreras C, Mañas A, Pérez-Martínez A, Casanova LF.   +20 more
europepmc   +1 more source

Molecular Competition for NKG2D [PDF]

Immunity, 2001
O'Callaghan, Christopher A, Cerwenka, Adelheid, Willcox, Benjamin E, Lanier, Lewis L, Bjorkman, Pamela J   +4 more
openaire   +1 more source

Newcastle Disease Virus - Induced Interferons Regulate PD-L1 and MICA Expression in Human Tumor and Normal Cells. [PDF]

Immunotargets Ther
Ginting TE, Larasati YO, Cornelia V, Hidayat NR, Christian S, Zarkasie K, Yusuf I.   +6 more
europepmc   +1 more source