Sodium valproate enhances efficacy of NKG2D CAR-T cells against glioblastoma
Chimeric antigen receptor T-cell (CAR-T) therapies have shown promise in glioblastoma clinical studies, but responses remain inconsistent due to heterogeneous tumor antigen expression and immune evasion post-treatment. NKG2D CAR-T cells have demonstrated
Junchen Liu +15 more
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NKG2D is an activating receptor expressed by all human NK cells and CD8 T cells. Harnessing the NKG2D/NKG2D ligand axis has emerged as a viable avenue for cancer immunotherapy.
Anthony V. Serritella +7 more
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Targeting the MICA/B-NKG2D axis in cancer: from molecular structure to immunotherapeutic strategies-a narrative review. [PDF]
Zheng Y, Ding W, Chen B, Geng C, Li X.
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Longitudinal Dynamics of NK-Cell Regulatory Signaling and IVIG Response in Kawasaki Disease. [PDF]
Kim Y +4 more
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Quantitative Analysis of Splenic Natural Killer Cells of Mice Using Imaging Flow Cytometry. [PDF]
Amin MN, Mostaq MS, Uddin MB, Liu YY.
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NK cell hyperactivation drives macrophage repolarization and limits M2 bias in pemphigus vulgaris. [PDF]
Hooda V +5 more
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[Research progress of the ULBP-NKG2D axis in autoimmune diseases]. [PDF]
Ma J, Wu J, Jin Y.
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Engineering NKG2D ligand affinity transforms EGFR-targeted NK cell engagers into high-potency effectors against pancreatic cancer. [PDF]
Lee SG +8 more
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cGAS/STING-mediated upregulation of NKG2D ligands in LSCs contributes to enhanced sensitivity to NK cells. [PDF]
Ouyang Y, Qin Y, Zhang Q, Zhu P, Zhu H.
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