Results 131 to 140 of about 21,131 (181)

The Metabolic Regulation of the NKG2D-Positive NK and T Cells and Their Role in Disease Progression. [PDF]

Biomolecules
Tang J, Lu Y, Chen M, Wu Q, Li Y, Qin Y, Liang S, Luo S, Liu K.   +8 more
europepmc   +1 more source

High-linear energy transfer radiation disrupts natural killer cell surveillance of senescent intestinal cells in the mouse intestine. [PDF]

Mol Biomed
Kumar S, Suman S, Li HH, Angdisen J, Datta K, Fornace AJ.   +5 more
europepmc   +1 more source

Modifier-Sensitive Phenotypic Divergence in XMEN Disease (MAGT1 Deficiency): Neurodegenerative and Immuno-Hematologic Trajectories. [PDF]

J Clin Med
Kural RF, Galata Z, Gumusburun R, Tunakan Dalgic C, Soyer N, Yazıcı H, Yuceyar AN, Subasıoglu A, Evcili I, Gungor B, Okan K, Soylu M, Uzunkopru C, Ardeniz O.   +13 more
europepmc   +1 more source

Off-the-shelf dual CAR-iNKT cell immunotherapy eradicates medullary and leptomeningeal high-risk KMT2A-rearranged leukemia.

Blood
Ren H, Elliott N, Lye B, Sharif Shohan MU, Cross JW, Field L, Ponnusamy K, Rice S, Jackson T, Leontari I, El Ouazzani N, Thomas R, Inglott S, Bartram J, Smith O, Bond J, Roberts IAG, Halsey C, Bashford-Rogers R, Milne TA, Roy A, Karadimitris A.   +21 more
europepmc   +1 more source

NKG2D Ligands in Cancer

, 2018
openaire   +1 more source

Targeting the NKG2D/NKG2D-L axis in acute myeloid leukemia

Biomedicine and Pharmacotherapy, 2021
Natural killer group 2, member D (NKG2D) receptor is a crucial activating receptor in the immune recognition and eradication of abnormal cells by natural killer (NK) cells, and T lymphocytes. NKG2D can transmit activation signals and activate the immune system by recognizing the NKG2D ligands (NKG2D-L) on acute myeloid leukemia (AML) cells ...
Yanqiu He, Na Wan
exaly   +3 more sources

NKG2D ligands in tumor immunity [PDF]

Oncogene, 2008
The activating receptor NKG2D (natural-killer group 2, member D) and its ligands play an important role in the NK, gammadelta(+) and CD8(+) T-cell-mediated immune response to tumors. Ligands for NKG2D are rarely detectable on the surface of healthy cells and tissues, but are frequently expressed by tumor cell lines and in tumor tissues.
Adelheid Cerwenka, Norman Nausch
exaly   +3 more sources

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NKG2D and its ligands

The International Journal of Biochemistry & Cell Biology, 2009
NKG2D is an activating immunoreceptor, first recognized on NK cells but subsequently found on gammadelta T cells, CD8(+) alphabeta T cells and macrophages. In NK cells, inhibitory signals are generally dominate over activating signals. However, activating signals mediated through engagement of NKG2D by its ligands on target cells can bypass signals ...
Peyman, Obeidy, Alexandra F, Sharland
openaire   +2 more sources

NKG2D and Related Immunoreceptors

2004
NK cells are crucial components of the innate immune system, capable of directly eliminating infected or tumorigenic cells and regulating down-stream adaptive immune responses. Unlike T cells, where the key recognition event driving activation is mediated by the unique T cell receptor (TCR) expressed on a given cell, NK cells express multiple ...
Roland K, Strong, Benjamin J, McFarland
openaire   +2 more sources