Results 111 to 120 of about 22,554 (186)

Effect of Heat Stress on the Expression of Circulating Cyto(chemo)kine and Inflammatory Markers in Broiler Chickens Selected for High- or Low-water Efficiency

Frontiers in Bioscience-Landmark
Background: Water scarcity is a current, significant global concern that will only increase under the pressure of climate change. Improving water efficiency of poultry is a new and promising area to help temper agriculture's future ...
Elizabeth S. Greene, Travis Tabler, Walter G. Bottje, Sara Orlowski, Sami Dridi   +4 more
doaj   +1 more source

Type I IFN-mediated regulation of IL-1 production in inflammatory disorders [PDF]

, 2018
Although contributing to inflammatory responses and to the development of certain autoimmune pathologies, type I interferons (IFNs) are used for the treatment of viral, malignant, and even inflammatory diseases.
Du Pasquier, Renaud, Guarda, Greta, Ludigs, Kristina, Parfenov, Valeriy   +3 more
core  

The role of inflammasome dysregulation in obstructive and non-obstructive azoospermia: a comparative molecular analysis of blood, tissue, and seminal plasma

Frontiers in Immunology
BackgroundTo address knowledge gaps, this study aimed to investigate the involvement of inflammasomes in the etiology of azoospermia. This study focused on the gene expression of key inflammasome components, including NLR family pyrin domain containing 3
Seyyed AmirHossein Mirghanizadeh Bafghi, Farzaneh Fesahat, Fateme Zare, Maryam Imani, Serajoddin Vahidi, Hossein Ansariniya, Hossein Ansariniya, Ali ZareHoroki, Hossein Hadinedoushan   +8 more
doaj   +1 more source

Involvement of role of HMGB1-NLRP3 pathway in systemic disorders

Frontiers in Cell and Developmental Biology
High mobility group box-1 (HMGB1) is a protein released from stressed or damaged cells that triggers immune activation and chronic inflammation.
Lei Yang, Xue Li, Xiaoming Zhu, Futao Ge, Yuantao Wang   +4 more
doaj   +1 more source

RBPMS2 can inhibit the NLRP3 / caspase-1 / GSDMD signaling pathway to resist pyroptosis in gastric cancer cells

Scientific Reports
Gastric cancer (GC) is one of the most common malignancies worldwide, and its development is closely associated with the abnormal expression of numerous genes. RNA - binding protein with multiple splicing 2 (RBPMS2), a member of the RNA - binding protein
Nailin Zhang, Lina Yan, Hua Cao, Nana Zhang, Tong Zhang, Shengjiang Guan, Qiquan Liu   +6 more
doaj   +1 more source

The effect of cortex eucommiae on alleviating lung injury induced by Haemophilus paragallinarum

Poultry Science
To analyze whether Cortex Eucommiae (CE) can inhibit pathological lung injury by regulating autophagy levels in chicks lung tissue and identify potential targets, thereby alleviating pneumonia damage caused by Haemophilus paragallinarum (Hp) infection ...
Bo Zhang, Bo Liao, Rou Sang, Rong Liao, Dengyao Xu, Yanhong Lv, Fangjie Li, Ke Li, Aiguo Xin   +8 more
doaj   +1 more source

Tmem30a protects against podocyte injury through suppression of pyroptosis

iScience
Summary: Podocytopathies, such as focal segmental glomerulosclerosis (FSGS), are characterized by podocyte injury and can easily progress to end-stage kidney disease. However, the mechanisms underlying podocyte injury remain unclear. We observed podocyte
Yanpei Hou, Sipei Chen, Lei Peng, Liming Huang, Huijian Zhang, Ping Zhang, Min Yu, Lin Xiong, Xiang Zhong, Wenjing Liu, Xianjun Zhu, Li Wang, Yi Li, Guisen Li   +13 more
doaj   +1 more source

Biological Therapies for Urate Lowering and Inflammation Control in Gout Management

Journal of Inflammation Research
Ye Zhou,1,* Hengyan Zhang,2,* Nian Liu,1,3,* Heguo Yan,1 Fanyu Meng,1 Jiangyun Peng1,3 1First Clinical Medical College, Yunnan University of Chinese Medicine, Kunming, People’s Republic of China; 2Department of Rheumatology ...
Zhou Y, Zhang H, Liu N, Yan H, Meng F, Peng J   +5 more
doaj  

Novel particulate vaccine candidates recombinantly produced by pathogenic and nonpathogenic bacterial hosts : a thesis presented in partial fulfillment of the requirements for the degree of Doctor of Philosophy in Microbiology at Massey University, Manawatu, New Zealand. [PDF]

, 2017
Polyhydroxyalkanoates (PHAs) are biopolyesters synthesized as small spherical cytoplasmic inclusion bodies by a range of bacteria. Recently, PHA beads have been investigated for use as a vaccine delivery platform by using engineered heterologous ...
Lee, Jason Wong
core  

Inter-relationships of galectin-3 and NLR family pyrin domain containing 3 inflammasomes with oral lichen planus: a preliminary cross-sectional in vitro study

BMC Oral Health
Background The nucleotide-binding oligomerization domain (NOD)-like receptor (NLR) family pyrin domain-containing 3 (NLRP3) inflammasome has been reported to be highly expressed in oral lesions with the potential for malignant development such as oral ...
Siting Chen, Xiaoheng Xu, Yang Liu, Yanmei Yao, Yinshen Yang, Wenxia Meng   +5 more
doaj   +1 more source