Results 21 to 30 of about 26,384,108 (210)
ASC filament formation serves as a signal amplification mechanism for inflammasomes [PDF]
, 2016 A hallmark of inflammasome activation is the ASC speck, a micrometre-sized structure formed by the inflammasome adaptor protein ASC (apoptosis-associated speck-like protein containing a CARD), which consists of a pyrin domain (PYD) and a caspase ...
Hiller, Sebastian +4 more
core +1 more source
Molecular Neurodegeneration, 2020 Background Acute glaucoma, characterized by a sudden elevation in intraocular pressure (IOP) and retinal ganglion cells (RGCs) death, is a major cause of irreversible blindness worldwide that lacks approved effective therapies, validated treatment ...
Hui Chen +13 more
doaj +1 more source
Anti-NLRP3 Inflammasome Natural Compounds: An Update
Biomedicines, 2021 The nucleotide-binding domain and leucine-rich repeat related (NLR) family, pyrin domain containing 3 (NLRP3) inflammasome is a multimeric protein complex that recognizes various danger or stress signals from pathogens, the host, and the environment ...
Baolong Liu, Jiujiu Yu
doaj +1 more source
NLRC4 (NLR Family, CARD domain containing 4) [PDF]
, 2008 Review on NLRC4 (NLR Family, CARD domain containing 4), with data on DNA, on the protein encoded, and where the gene is ...
Radha, V, Swarup, G, Kumar, Y
core +1 more source
Pyroptosis-Mediated Damage Mechanism by Deoxynivalenol in Porcine Small Intestinal Epithelial Cells
Toxins, 2023 Deoxynivalenol (DON) is known as a vomitoxin, which frequently contaminates feedstuffs, such as corn, wheat, and barley. Intake of DON-contaminated feed has been known to cause undesirable effects, including diarrhea, emesis, reduced feed intake ...
Tae Hong Kang +4 more
doaj +1 more source
Study of protein structure by electron microscopy and single particle image processing [PDF]
, 2015 The molecular assemblies form an important role in the understanding the machinery of living cells. These assemblies with thickness less than 1000nm and exhibiting different shapes, size and biochemical states are studied using Transmission Electron ...
Dandey, Venkata Prasad
core +1 more source
The Role of NLRP3 Inflammasomes in Trained Immunity
Frontiers in Bioscience-Landmark, 2023 Inflammasomes are cytosolic multi-protein complexes that play an important role in the innate immune system, inducing cytokine maturation and pyroptosis.
Gilyoung Lee +3 more
doaj +1 more source
Pyrin Domain (PYD)-containing Inflammasome in Innate Immunity [PDF]
, 2011 Inflammasome is a cytosolic multiprotein complex to activate caspase-1 leading to the subsequent processing of inactive pro-interleukin-1-beta (Pro-IL-1beta) into its active interleukin-1 beta (IL-1beta) in response to pathogen- or danger-associated ...
유제욱
core +1 more source
The CATH database: an extended protein family resource for structural and functional genomics [PDF]
, 2003 The CATH database of protein domain structures (http://www.biochem.ucl.ac.uk/bsm/cath_new) currently contains 34 287 domain structures classified into 1383 superfamilies and 3285 sequence families.
Pearl, F.M.G. +8 more
core +1 more source
, 2022 Herpes simplex virus type 1 (HSV-1) is a highly prevalent virus in humans and causes severe forms of inflammation, such as herpes simplex encephalitis (HSE).
Qiongzhen Zeng (11439295) +11 more
core +1 more source