Results 261 to 270 of about 106,008 (282)

Cigarette smoking induces NLRP3 inflammasome activation in patients with atrial fibrillation. [PDF]

Am J Physiol Heart Circ Physiol
Sarode G, Diloretto DA, Roslan FF, Pandita P, Overton J, Srivatsa U, Catrip JM, Liem DA, Bang H, Cadeiras M, Chiamvimonvat N, Sirish P.   +11 more
europepmc   +1 more source

ML345 is a potent and selective NLRP3 inflammasome inhibitor with anti-inflammatory activity. [PDF]

Mol Biomed
Lin H, Liang X, Hao W, Lu X, Li B, Wang X.   +5 more
europepmc   +1 more source

The NOX2-ROS-NLRP3 inflammasome axis in traumatic brain injury. [PDF]

J Neuroinflammation
Laabei J, Vegliante G, Strogulski NR, Douglas C, Threja S, Pearson A, Nkiliza A, Hanscom M, Dias Filogonio Emediato I, Crawford F, Ojo J, Loane DJ.   +11 more
europepmc   +1 more source

Parthenolide attenuated the endometriosis-like lesions by activating autophagy and suppressing NLRP3 inflammasome activity. [PDF]

Iran J Basic Med Sci
Jin L, Fu T, Chi C, Zhou J, Lin J, Hou W.   +5 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

NLRP3 inflammasome in sepsis (Review)

Molecular Medicine Reports, 2021
Sepsis is an imbalanced response to infection that leads to life-threatening organ dysfunction. Although an increasing number of anti-inflammatory drugs are available, the options for treating sepsis remain limited. Therefore, it is imperative to understand the pathogenesis and pathophysiology of sepsis and develop novel therapeutic targets to treat ...
Xueyan, Shi, Sichuang, Tan, Sipin, Tan
openaire   +2 more sources

Vasculitis and the NLRP3 inflammasome

Current Opinion in Rheumatology, 2023
Purpose of review Vasculitis are a group of heterogeneous conditions characterized by chronic inflammation of blood vessels, leading to tissue destruction and organ failure. Vasculitis is an inflammatory process in which immune effector cells infiltrate blood vessels and surrounding tissues.
Kamel, Hamzaoui, Agnès, Hamzaoui
openaire   +2 more sources

NLRP3 inflammasome in neurodegenerative disease

Translational Research, 2023
Neurodegenerative diseases are characterized by a dysregulated neuro-glial microenvironment, culminating in functional deficits resulting from neuronal cell death. Inflammation is a hallmark of the neurodegenerative microenvironment and despite a critical role in tissue homeostasis, increasing evidence suggests that chronic inflammatory insult can ...
Faith L. Anderson, Karl E. Biggs, Brynn E. Rankin, Matthew C. Havrda   +3 more
openaire   +2 more sources

NLRP3 inflammasome inhibitor INF39 attenuated NLRP3 assembly in macrophages

International Immunopharmacology, 2021
INF39 is a nontoxic, irreversible, acrylate-based NLRP3 inhibitor and a further optimization of ethyl 2-((2-chlorophenyl) hydroxyl) methyl) acrylate (INF4E). However, the detail mechanism and the direct target of its anti-inflammatory activity is not clear. Here, we show that INF39 is a specific inhibitor for NLRP3 inflammasome activation.
Yuhua Shi, Qian Lv, Mengjie Zheng, Hongxiang Sun, Fushan Shi   +4 more
openaire   +2 more sources