Exploring biomarkers of neurodegeneration in epilepsy: Critical insights
Abstract The advent of biofluid biomarkers for neurodegenerative disorders has precipitated a surge in recent evidence regarding their role in epilepsy. In this literature review, we examine the diagnostic, prognostic, and therapeutic potential of several biomarkers, including amyloid‐beta (Aβ) protein, total (t‐tau), phosphorylated tau (p‐tau) protein,
Rida Farhan+7 more
wiley +1 more source
A neuroeconomic theory of bidirectional synaptic plasticity and addiction [PDF]
Neuronal mechanisms underlying addiction have been attracting attention in neurobiology, economics, neuropsychiatry, and neuroeconomics. This paper proposes a possible link between economic theory of addiction (Becker and Murphy, 1988) and neurobiological theory of bidirectional synaptic plasticity (Bienenstock, Cooper, Munro, 1982) based on recent ...
arxiv
Interaction of GABA and Excitatory Amino Acids in the Basolateral Amygdala: Role in Cardiovascular Regulation [PDF]
Activation of the amygdala in rats produces cardiovascular changes that include increases in heart rate and arterial pressure as well as behavioral changes characteristic of emotional arousal.
Cook, Jennifer C.+3 more
core +2 more sources
Convulsions induced by centrally administered NMDA in mice: effects of NMDA antagonists, benzodiazepines, minor tranquilizers and anticonvulsants [PDF]
Jean‐Luc Moreau+2 more
openalex +1 more source
Voltage clamp analysis of nonlinear dendritic propertie in prepositus hypoglossi neurons [PDF]
The nonlinear properties of the dendrites in prepositus hypoglossi neurons are involved in maintenance of eye position. The biophysical properties of these neurons are essential for the operation of the vestibular neural integrator that converts a head velocity signal to one that controls eye position.
arxiv
A comparison between the in vivo and in vitro activity of five potent and competitive NMDA antagonists [PDF]
David Lodge+8 more
openalex +1 more source
Erratum: Corrigendum: NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurones [PDF]
Amy B. MacDermott+4 more
openalex +1 more source
Abstract New Onset Refractory Status Epilepticus (NORSE) is a rare and severe condition characterized by refractory seizures in individuals without a prior history of epilepsy. This case report describes a 37‐year‐old woman diagnosed with anti‐glutamic acid decarboxylase 65 (anti‐GAD65) antibody‐positive encephalitis‐related NORSE.
Mingyu Li+9 more
wiley +1 more source
Neurokinematic Modeling of Complex Swimming Patterns of the Larval Zebrafish [PDF]
Larval zebrafish exhibit a variety of complex undulatory swimming patterns. This repertoire is controlled by the 300 neurons projecting from brain into spinal cord. Understanding how descending control signals shape the output of spinal circuits, however, is nontrivial.
arxiv
N-Methyl-D-aspartate (NMDA) receptors are a principal subtype of excitatory ligand-gated ion channels with crucial roles in a variety of physiological and pathological processes in the mammalian central nervous system (CNS).
Noritaka Nakamichi, Yukio Yoneda
doaj