Results 21 to 30 of about 43,559 (247)

Detection of NMDARs Antibodies in Encephalitis [PDF]

, 2017
There is a range of diseases of the brain that are associated with rapidly developing inflammation. These conditions are called encephalitis, and can be caused by infections, or autoimmune disorders when the subject's immune system reacts against host proteins.
Gastaldi, M, Waters, P, Vincent, A
openaire   +3 more sources

Factors Influencing the Withdrawal of Antiepileptic Drugs in Adult Patients with Symptomatic Seizures Secondary to Neuronal Surface Antibodies-Associated Autoimmune Encephalitis

Journal of Inflammation Research, 2022
Fang Huang, Yu Wu, Weidong Nong, Fengping Mao, Xiaoli Cao, Wen Huang, Jinou Zheng Department of Neurology, The First Affiliated Hospital of Guangxi Medical University, Guangxi, People’s Republic of ChinaCorrespondence: Wen Huang; Jinou Zheng, Department ...
Huang F, Wu Y, Nong W, Mao F, Cao X, Huang W, Zheng J   +6 more
doaj  

Extrasynaptic NR2D-Containing NMDARs Are Recruited to the Synapse during LTP of NMDAR-EPSCs [PDF]

The Journal of Neuroscience, 2008
Long-term potentiation of NMDA-receptor-mediated synaptic transmission (NMDAR-LTP) is a little-understood form of plasticity. In the present study, we investigated whether NMDAR-LTP in the dentate gyrus involves recruitment of extrasynaptic NMDARs, because NMDARs are expressed both synaptically and extrasynaptically with evidence for subtype ...
Harney, S, Jane, DE, Anwyl, R
openaire   +3 more sources

Entwicklung eines hochaffinen NMDAR-Fc-Fusionsproteins als "Köder" für den Nachweis und die Beseitigung von Autoantikörpern bei NMDAR-Enzephalitis [PDF]

, 2023
The most common form of autoimmune encephalitis is the N-methyl-D-aspartate receptor (NMDAR) encephalitis, which is characterized by a variety of complex neuropsychiatric symptoms.
Steinke, Stephan
core   +1 more source

NMDA receptor antagonists as potential therapy in cerebellar degenerative disorders

Анналы клинической и экспериментальной неврологии, 2022
Cerebellar degeneration remains a poorly studied topic. Excitotoxicity, i.e. neuronal damage and death due to excess activation of postsynaptic N-methyl-D-aspartate receptors (NMDAR) by glutamate, is considered to be a universal mechanism of most ...
Olga S. Belozor, Andrey N. Shuvaev, Yana V. Fritsler, Anton N. Shuvaev   +3 more
doaj   +1 more source

Human Autoantibodies Against N-Methyl-D-Aspartate Receptor Modestly Alter Dopamine D1 Receptor Surface Dynamics

Frontiers in Psychiatry, 2019
Circulating autoantibodies directed against extracellular domains of the glutamatergic N-methyl-D-aspartate receptors (NMDAR-Ab) elicit psychotic symptoms in humans and behavioral deficits in animal models.
Hélène Gréa, Hélène Gréa, Delphine Bouchet, Delphine Bouchet, Véronique Rogemond, Véronique Rogemond, Véronique Rogemond, Nora Hamdani, Nora Hamdani, Nora Hamdani, Nora Hamdani, Emmanuel Le Guen, Emmanuel Le Guen, Emmanuel Le Guen, Emmanuel Le Guen, Ryad Tamouza, Ryad Tamouza, Ryad Tamouza, Ryad Tamouza, Estelle Darrau, Christine Passerieux, Christine Passerieux, Christine Passerieux, Jérôme Honnorat, Jérôme Honnorat, Jérôme Honnorat, Marion Leboyer, Marion Leboyer, Marion Leboyer, Marion Leboyer, Laurent Groc, Laurent Groc   +31 more
doaj   +1 more source

Symptomatologic pathomechanism of -methyl D-aspartate receptor encephalitis [PDF]

Encephalitis, 2021
N-methyl D-aspartate receptor (NMDAR) encephalitis is a well-characterized clinical syndrome. The main molecular mechanism of NMDAR encephalitis is autoantibody-mediated NMDAR hypofunction in the neuronal synapse.
Woo-Jin Lee
doaj   +1 more source

Spinophilin limits GluN2B-containing NMDAR activity and sequelae associated with excessive hippocampal NMDAR function

, 2021
N-methyl-D-Aspartate receptors (NMDARs) are calcium-permeable ion channels that are ubiquitously expressed within the glutamatergic postsynaptic density. Phosphorylation of NMDAR subunits defines receptor activity and surface localization.
Bansal, Ruchi, Berbari, Nicolas F., Baucum, Anthony J., II., Salek, Asma B.   +3 more
core   +1 more source

Suppression of synaptic plasticity by cerebrospinal fluid from anti-NMDA receptor encephalitis patients

Neurobiology of Disease, 2012
The functional effects of cerebrospinal fluid (CSF) from patients with anti-NMDA receptor (NMDAR) encephalitis on the NMDAR-mediated synaptic plasticity were evaluated by using mouse hippocampus slices.
Qing Zhang, Keiko Tanaka, Peng Sun, Michiyo Nakata, Ryo Yamamoto, Kenji Sakimura, Makoto Matsui, Nobuo Kato   +7 more
doaj   +1 more source

Pulsed Radiofrequency Decreases pERK and Affects Intracellular Ca2+ Influx, Cytosolic ATP Level, and Mitochondrial Membrane Potential in the Sensitized Dorsal Root Ganglion Neuron Induced by N-Methyl D-Aspartate [Corrigendum]

Journal of Pain Research, 2023
Laksono RM, Kalim H, Rohman MS, Widodo N, Ahmad MR, Halim W. J Pain Res. 2023;16:1697–1711. The authors have advised affiliation 1 on page 1697 is incorrect.
Laksono RM, Kalim H, Rohman MS, Widodo N, Ahmad MR, Halim W   +5 more
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