Results 161 to 170 of about 10,005 (213)

Endothelial C/EBPβ/AEP pathway drives vascular deterioration and systemic aging. [PDF]

Sci Adv
Li B, Nie S, Wang M, An J, Qian Z, Meng X, Edgington-Mitchell LE, Zhang Z, Yang X, Ye K.   +9 more
europepmc   +1 more source

Nicotinamide mononucleotide enhances anti-tumor effect by resetting macrophages toward the inflammatory M1-like phenotype. [PDF]

Mol Ther Oncol
Xu H, Wan MCT, Wong CCC, Qin S, Wen Y, Wang J, Chen Z.   +6 more
europepmc   +1 more source

Deacetylation of SRF catalyzed by SIRT7 protects against abdominal aortic aneurysm formation. [PDF]

Exp Mol Med
Xiong Y, Chen J, Lu W, Liu Y, Sheng C, Liu S, Xu B, Li Y, Pan B, Wang W.   +9 more
europepmc   +1 more source

Molecular Engineering of Nicotinamide Riboside Kinase and Process Optimization for Efficient Nicotinamide Mononucleotide Production. [PDF]

Foods
Ma D, Liu R, Bao T, Yang J, Zhang H, Hu X.   +5 more
europepmc   +1 more source

Erratum: [Corrigendum] Endogenous Nampt upregulation is associated with diabetic nephropathy inflammatory-fibrosis through the NF-κB p65 and Sirt1 pathway; NMN alleviates diabetic nephropathy inflammatory-fibrosis by inhibiting endogenous Nampt. [PDF]

Exp Ther Med
Chen Y, Liang Y, Hu T, Wei R, Cai C, Wang P, Wang L, Qiao W, Feng L.   +8 more
europepmc   +1 more source

Sarcopenia and satellite cell homeostasis disruption: the dual function of NAD+ metabolism. [PDF]

Front Nutr
Li C, Ai Y, Yan J, Wu S.
europepmc   +1 more source

Safety of beta-nicotinamide mononucleotide (β-NMN) pursuant the regulation (EU) 2015/2283 and the bioavailability of nicotinamide from this source in the context of Directive 2002/46/EC. [PDF]

EFSA J
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Turck D, Bohn T, Cámara M, Castenmiller J, De Henauw S, Jos Á, Maciuk A, Mangelsdorf I, McNulty B, Naska A, Pentieva K, Siani A, Thies F, Aguilera-Gómez M, Cubadda F, Frenzel T, Gundert-Remy U, Marcon F, McArdle HJ, Neuhäuser-Berthold M, Maradona MP, Siskos A, Wright M, Beneventi E, Rossi A, Magani M, Hirsch-Ernst KI.   +28 more
europepmc   +1 more source

Therapeutic effects of nicotinamide mononucleotide and Indian gooseberry in oxidative stress and inflammation-induced damage on human retinal pigment epithelial cells: A pilot study. [PDF]

J Biomed Res
Lee D, Nahar JS, Kim S, Lim SS.
europepmc   +1 more source

Characterization of Two NMN Deamidase Mutants as Possible Probes for an NMN Biosensor [PDF]

International Journal of Molecular Sciences, 2021
Nicotinamide mononucleotide (NMN) is a key intermediate in the nicotinamide adenine dinucleotide (NAD+) biosynthesis. Its supplementation has demonstrated beneficial effects on several diseases. The aim of this study was to characterize NMN deamidase (PncC) inactive mutants to use as possible molecular recognition elements (MREs) for an NMN-specific ...
Alessandra Camarca, Adolfo Amici, Sabato D'Auria   +2 more
exaly   +7 more sources

Nicotinamide mononucleotide (NMN) intake increases plasma NMN and insulin levels in healthy subjects

Clinical Nutrition ESPEN, 2023
Nicotinamide adenine dinucleotide (NAD+) is a coenzyme of the NAD+-dependent protein deacetylase sirtuin-1 (SIRT1). An increase in NAD+ concentration induces SIRT1 activation that results in various health benefits. Since nicotinamide mononucleotide (NMN) is a precursor of NAD+, NMN ingestion is expected to have multiple health benefits such as ...
Takuya Yamane, Susumu Uchiyama
exaly   +3 more sources