The Diverse Functions of Non-Essential Amino Acids in Cancer. [PDF]
Cancers (Basel), 2019 Far beyond simply being 11 of the 20 amino acids needed for protein synthesis, non-essential amino acids play numerous important roles in tumor metabolism. These diverse functions include providing precursors for the biosynthesis of macromolecules, controlling redox status and antioxidant systems, and serving as substrates for post-translational and ...
Choi BH, Coloff JL.
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Amino acid metabolism of Astacus leptodactylus (Esch.)—II. Biosynthesis of the non-essential amino acids [PDF]
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1975 1. 1. Incubation of Astacus leptodactylus with U-14C-glucose or 1-14C-acetate induced labelling of α- and β-alanine, aspartic and glutamic acids, glutamine, glycine, proline and serine. No radioactivity was incorporated into arginine, asparagine, histidine, isoleucine, leucine, lysine, ornithine, phenylalanine, taurine, threonine, tyrosine and valine.
Marrewijk, Willibrordus J.A. +1 more
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Sex Differences in the Utilization of Essential and Non‐Essential Amino Acids in Lepidoptera [PDF]
The FASEB Journal, 2017 The different reproductive strategies of males and females have selected for differences in function and behavior that may translate into differences in resource use. Here we studied sexual differences in the utilization of essential and non‐essential amino acids by the Carolina sphinx moth ( Manduca sexta ...
Eran Levin +2 more
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Effects of Non-Essential Amino Acids on Knee Joint Conditions in Adults: A Randomised, Double-Blind, Placebo-Controlled Trial. [PDF]
Nutrients, 2022 Joint problems impair performance during exercise and daily activities and influence quality of life. The present study aimed to examine the effects of a combination of six non-essential amino acids (6AA) on joint conditions in an adult population.
Takeuchi F +4 more
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Amounts of essential and non-essential amino acids and the ratio in Lithuania bred cattle meat [PDF]
Biotechnology in Animal Husbandry, 2014 The aim of the research was to determine the amounts of essential and non-essential amino acids and the ratio in various breed cattle meat. The content of amino acids and the ratio at the longest dorsal muscle (musculus longissimus dorsi) was determined ...
Jukna Vigilijus +2 more
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The Role of Non-essential Amino Acids in T Cell Function and Anti-tumour Immunity. [PDF]
Arch Immunol Ther Exp (Warsz), 2021 AbstractT cell activation, differentiation and proliferation is dependent upon and intrinsically linked to a capacity to modulate and adapt cellular metabolism. Antigen-induced activation stimulates a transcriptional programme that results in metabolic reprogramming, enabling T cells to fuel anabolic metabolic pathways and provide the nutrients to ...
Hope HC, Salmond RJ.
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Bridging epigenetics and metabolism: role of non-essential amino acids. [PDF]
Epigenetics, 2013 Recent research suggests that chromatin-modifying enzymes are metabolic sensors regulating gene expression. Epigenetics is linked to metabolomics in response to the cellular microenvironment. Specific metabolites involved in this sensing mechanism include S-adenosylmethionine, acetyl-CoA, alphaketoglutarate and NAD (+) .
Phang JM, Liu W, Hancock C.
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Phase-separation propensity of non-ionic amino acids in peptide-based complex coacervation systems [PDF]
, 2022 Uncovering the sequence-encoded molecular grammar that governs the liquid–liquid phase separation (LLPS) of proteins is a crucial issue to understand dynamic compartmentalization in living cells and the emergence of protocells. Here, we present a model
Kentaro, Shiraki +13 more
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EFFECTS OF BREED AND SEASONAL VARIATIONS ON SEMINAL PLASMA ESSENTIAL AND NON ESSENTIAL < AMINO ACIDS CONTENTS FOR RAMS AT NORTH WEST COAST OF EGYPT [PDF]
Journal of Animal and Poultry Production, 2002 Fifteen rams of three breeds, five Barki, five local Awassi and five imported Awassi breed were used in the present study. The study was aimed to investigate the effects of breed and seasonal vartanons on seminal plasma amino acids concentration ...
M. Anwar,
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Plasma Amino Acids Metabolomics' Important in Glucose Management in Type 2 Diabetes
Frontiers in Pharmacology, 2021 The perturbation in plasma free amino acid metabolome has been observed previously in diabetes mellitus, and is associated with insulin resistance as well as the onset of cardiovascular disease in this population.
Abdelrahim Alqudah +4 more
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