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Non-HLA immunogenetics in hematopoietic stem cell transplantation
Current Opinion in Immunology, 2005Hematopoietic stem cell transplantation (HSCT) provides a unique environment in which to evaluate the role of immunogenetics of both the donor and the recipient to success of the procedure. The central role of HLA matching in HSCT has been established; however, recipients of allogeneic HSCT incur the risk of graft versus host disease (GVHD) even when ...
Anne M, Dickinson, Dominique, Charron
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Non-HLA Antibodies in Clinical Transplantation.
Clinical transplants, 2018Organ transplantation overcomes conservative therapy to improve patient longevity. Despite the improvement of donor-recipient compatibility tests and intensified immunosuppressive agents, long-term graft survival remains poor because of acute and chronic injury driven by immunologic and non-immunologic factors. The significant immunological barrier for
Chitranon, Chan-On, Minnie, Sarwal
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A Reevaluation of the Role of IgM Non-HLA Antibodies in Cardiac Transplantation
Transplantation, 2009Preexisting IgG antibodies to donor human leukocyte antigens (HLA) are a risk factor for rapid allograft rejection. However, non-HLA antibodies, of the IgM class, also called autoreactive antibodies, are not believed to affect graft survival. The aim of this study was to determine the incidence and clinical relevance of pretransplant lymphocytotoxic ...
John D, Smith +10 more
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HLA and Non-HLA Genes in Celiac Disease
2008Celiac disease (CD) is a multifactorial disorder in which the combination of several genetic factors together with an environmental trigger is necessary for development of the disease.
A. Zhernakova, C. Wijmenga
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Non-HLA Gene Polymorphisms in Stem Cell Transplantation
2007An increasing number of gene polymorphisms of immune regulatory molecules are being associated with clinical performance following stem cell transplantation (SCT). These polymorphisms affect structural or regulatory changes on immune regulatory molecules including cytokines .
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Non-HLA antibodies in alloimmunized patients
Human Immunology, 1982Elaine Reed +5 more
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HLA-DR15 Molecules Jointly Shape an Autoreactive T Cell Repertoire in Multiple Sclerosis
Cell, 2020Christian Münz +2 more
exaly
The dilemma of the role of the non‐HLA antibodies in AMR
Clinical TransplantationMaria T. Gamero +7 more
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