Results 11 to 20 of about 209,431 (210)

Modulation of the Wound Healing through Noncoding RNA Interplay and GSK-3β/NF-κB Signaling Interaction

open access: yesInternational Journal of Genomics, 2021
Diabetic foot ulcers are seriously endangering the physical and mental health of patients. Due to the long duration of inflammation, the treatment of nonhealing wounds in diabetes is one of the most prominent healthcare problems in the world. The nuclear
Xianyi Wang   +3 more
doaj   +1 more source

A promising nucleic acid therapy drug: DNAzymes and its delivery system

open access: yesFrontiers in Molecular Biosciences, 2023
Based on the development of nucleic acid therapeutic drugs, DNAzymes obtained through in vitro selection technology in 1994 are gradually being sought.
Lang Xiao   +12 more
doaj   +1 more source

EBV Noncoding RNAs [PDF]

open access: yes, 2015
EBV expresses a number of viral noncoding RNAs (ncRNAs) during latent infection, many of which have known regulatory functions and can post-transcriptionally regulate viral and/or cellular gene expression. With recent advances in RNA sequencing technologies, the list of identified EBV ncRNAs continues to grow.
Rebecca L, Skalsky, Bryan R, Cullen
openaire   +2 more sources

A multi-tissue transcriptomic landscape of female mice in estrus and diestrus provides clues for precision medicine

open access: yesFrontiers in Cell and Developmental Biology, 2022
Female reproductive cycle, also known as menstrual cycle or estrous cycle in primate or non-primate mammals, respectively, dominates the reproductive processes in non-pregnant state.
Yiran Zhou   +14 more
doaj   +1 more source

The Challenges and Opportunities of lncRNAs in Ovarian Cancer Research and Clinical Use [PDF]

open access: yes, 2020
[Abstract] Ovarian cancer is one of the most lethal gynecological malignancies worldwide because it tends to be detected late, when the disease has already spread, and prognosis is poor.
Barreiro-Alonso, Aida   +6 more
core   +1 more source

smORFunction: a tool for predicting functions of small open reading frames and microproteins

open access: yesBMC Bioinformatics, 2020
Background Small open reading frame (smORF) is open reading frame with a length of less than 100 codons. Microproteins, translated from smORFs, have been found to participate in a variety of biological processes such as muscle formation and contraction ...
Xiangwen Ji, Chunmei Cui, Qinghua Cui
doaj   +1 more source

Profiling of RNAs from Human Islet-Derived Exosomes in a Model of Type 1 Diabetes [PDF]

open access: yes, 2019
Type 1 diabetes (T1D) is characterized by the immune-mediated destruction of insulin-producing islet β cells. Biomarkers capable of identifying T1D risk and dissecting disease-related heterogeneity represent an unmet clinical need.
Evans-Molina, Carmella   +4 more
core   +2 more sources

MicroRNA-486-5p Suppresses Lung Cancer via Downregulating mTOR Signaling In Vitro and In Vivo

open access: yesFrontiers in Oncology, 2021
Lung cancer is one of the central causes of tumor-related deaths globally, of which non-small cell lung cancer (NSCLC) takes up about 85%. As key regulators of various biological processes, microRNAs (miRNAs) have been verified as crucial factors in ...
Lei Ding   +7 more
doaj   +1 more source

Long noncoding RNAs in prostate cancer: overview and clinical implications. [PDF]

open access: yes, 2016
Prostate cancer is the second most common cause of cancer mortality among men in the United States. While many prostate cancers are indolent, an important subset of patients experiences disease recurrence after conventional therapy and progresses to ...
Feng, Felix Y, Malik, Bhavna
core   +3 more sources

Role of noncoding RNA in vascular remodelling [PDF]

open access: yes, 2016
Purpose of review: Noncoding RNAs (ncRNAs), such as microRNAs (miRNAs) and long noncoding RNAs (lncRNAs) are becoming fundamentally important in the pathophysiology relating to injury-induced vascular remodelling.
Baker, Andrew H.   +2 more
core   +1 more source

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