Results 11 to 20 of about 224,829 (339)
Microbiology Spectrum, 2019 ABSTRACT Regulatory RNAs, present in many bacterial genomes and particularly in pathogenic bacteria such as Staphylococcus aureus , control the expression of genes encoding virulence factors or metabolic proteins.
Desgranges, E. +4 more
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Noncoding RNA in Cholangiocarcinoma [PDF]
Seminars in Liver Disease, 2018 AbstractCholangiocarcinomas (CCAs) are tumors with a dismal prognosis. Early diagnosis is a key challenge because of the lack of specific symptoms, and the curability rate is low due to the difficulty in achieving a radical resection and the intrinsic chemoresistance of CCA cells.
Salati, Massimiliano, Braconi, Chiara
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, 2015 EBV expresses a number of viral noncoding RNAs (ncRNAs) during latent infection, many of which have known regulatory functions and can post-transcriptionally regulate viral and/or cellular gene expression. With recent advances in RNA sequencing technologies, the list of identified EBV ncRNAs continues to grow.
Rebecca L, Skalsky, Bryan R, Cullen
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Frontiers in Cell and Developmental Biology, 2022 Female reproductive cycle, also known as menstrual cycle or estrous cycle in primate or non-primate mammals, respectively, dominates the reproductive processes in non-pregnant state.
Yiran Zhou +14 more
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smORFunction: a tool for predicting functions of small open reading frames and microproteins
BMC Bioinformatics, 2020 Background Small open reading frame (smORF) is open reading frame with a length of less than 100 codons. Microproteins, translated from smORFs, have been found to participate in a variety of biological processes such as muscle formation and contraction ...
Xiangwen Ji, Chunmei Cui, Qinghua Cui
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Profiling of RNAs from Human Islet-Derived Exosomes in a Model of Type 1 Diabetes [PDF]
, 2019 Type 1 diabetes (T1D) is characterized by the immune-mediated destruction of insulin-producing islet β cells. Biomarkers capable of identifying T1D risk and dissecting disease-related heterogeneity represent an unmet clinical need.
Evans-Molina, Carmella +4 more
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MicroRNA-486-5p Suppresses Lung Cancer via Downregulating mTOR Signaling In Vitro and In Vivo
Frontiers in Oncology, 2021 Lung cancer is one of the central causes of tumor-related deaths globally, of which non-small cell lung cancer (NSCLC) takes up about 85%. As key regulators of various biological processes, microRNAs (miRNAs) have been verified as crucial factors in ...
Lei Ding +7 more
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A Novel Gonadotropin-Releasing Hormone 1 (Gnrh1) Enhancer-Derived Noncoding RNA Regulates Gnrh1 Gene Expression in GnRH Neuronal Cell Models. [PDF]
, 2016 Gonadotropin-releasing hormone (GnRH), a neuropeptide released from a small population of neurons in the hypothalamus, is the central mediator of the hypothalamic-pituitary-gonadal axis, and is required for normal reproductive development and function ...
Brusman, Liza E +4 more
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The Challenges and Opportunities of lncRNAs in Ovarian Cancer Research and Clinical Use [PDF]
, 2020 [Abstract] Ovarian cancer is one of the most lethal gynecological malignancies worldwide because it tends to be detected late, when the disease has already spread, and prognosis is poor.
Barreiro-Alonso, Aida +6 more
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Uirusu, 2009 Many lines of recent evidence indicate that non-coding RNAs including micro RNAs (miRNAs) and small interfering RNAs (siRNAs) play an important role in the control of gene expression in diverse cellular processes and in defense responses against molecular parasites such as viruses and transposons.
Hiro-oki, Iwakawa, Testuro, Okuno
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