Results 41 to 50 of about 532,604 (238)

Saturated Fats: Time to Assess Their Beneficial Role in a Healthful Diet

Dietetics
Saturated fats are widely seen as undesirable components of a healthy diet, as a result of their illusory association with elevated serum cholesterol. The regulation of serum cholesterol is now better understood and a lack of polyunsaturated fatty acids,
Glen D. Lawrence
doaj   +1 more source

Effects of nonesterified fatty acids on the synthesis and assembly of very low density lipoprotein in bovine hepatocytes in vitro.

Journal of Dairy Science, 2014
High serum concentrations of nonesterified fatty acids (NEFA), which may affect the synthesis and assembly of very low density lipoproteins (VLDL), are associated with fatty liver during the early lactation period.
Leihong Liu, Xinwei Li, Yu Li, Yuan Guan, Yuxiang Song, Liheng Yin, H. Chen, L. Lei, Juxiong Liu, Xiaobing Li, Zhe Wang, Xiaoyu Yang, Guowen Liu   +12 more
semanticscholar   +1 more source

Identification of Anti-Long Chain Saturated Fatty Acid IgG Antibodies in Serum of Patients with Type 2 Diabetes

Mediators of Inflammation, 2015
High levels of serum long chain saturated fatty acids (LCSFAs) have been associated with inflammation in type 2 diabetes. Dietary SFAs can promote inflammation, the secretion of IgG antibodies, and secretion of the proinflammatory cytokine IL-1β.
Dequina A. Nicholas, Lorena M. Salto, Ava M. Boston, Nan Sun Kim, Marco Larios, W. Lawrence Beeson, Anthony F. Firek, Carlos A. Casiano, William H. R. Langridge, Zaida Cordero-MacIntyre, Marino De Leon   +10 more
doaj   +1 more source

Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease.

Journal of Clinical Investigation, 2005
Nonalcoholic fatty liver disease (NAFLD) is characterized by the accumulation of excess liver triacylglycerol (TAG), inflammation, and liver damage.
Kerry L Donnelly, Coleman I. Smith, S. Schwarzenberg, J. Jessurun, M. Boldt, E. Parks   +5 more
semanticscholar   +1 more source

Concentrations of nonesterified fatty acids and glucose in blood of periparturient dairy cows are indicative of pregnancy success at first insemination.

Journal of Dairy Science, 2013
Greater blood concentrations of nonesterified fatty acids (NEFA) and lesser blood concentrations of glucose are indicative of the normal process of nutrient partitioning that occurs in early postpartum dairy cows.
H. Garverick, M. Harris, R. Vogel-Bluel, J. D. Sampson, J. F. Bader, W. Lamberson, J. Spain, M. Lucy, R. S. Youngquist   +8 more
semanticscholar   +1 more source

Chylomicron remnants and nonesterified fatty acids differ in their ability to inhibit genes involved in lipogenesis in rats. [PDF]

J Nutr, 2011
Primary hepatocytes treated with nonesterified PUFA have been used as a model for analyzing the inhibitory effects of dietary polyunsaturated fats on lipogenic gene expression.
Kohan AB, Qing Y, Cyphert HA, Tso P, Salati LM.   +4 more
europepmc   +2 more sources

The Long Noncoding RNA ΒFaar Promotes White Adipose Tissue Browning and Prevents Diet‐Induced Obesity

Advanced Science, EarlyView.
βFaar selectively targets and inhibits the GTPase activity of the RAB18 protein, thereby reducing LD volume. Conversely, βFaar promotes nuclear translocation of the transcription factor IRF4 in inguinal white adipose tissue (iWAT), facilitating the browning of white adipose tissue and attenuating body fat accumulation.
Yue Yang, Bin Huang, Baixue Sha, Danni Gao, Yimeng Qin, Ziyi Li, Xi Chen, Yinuo Jin, Yi Pan, Yanfeng Zhang, Yumeng Shen, Yu Liu, Liang Jin, Fangfang Zhang   +13 more
wiley   +1 more source

Compensation Response to Hepatic Gluconeogenesis via β‐Hydroxybutyrylation of FBP1 and PCK1 in Dairy Cows

Animal Research and One Health, EarlyView.
(1) Kbhb modification of FBP1 and PCK1 is involved in regulation of the gluconeogenesis pathway. (2) Kbhb of FBP1 and PCK1 is catalyzed by p300 and removed by HDACs. (3) BHB induced an increase in the enzymatic activity of FBP1 and PCK1 through Kbhb modification at the K43 site of FBP1 and the K191 site of PCK1.
DingPing Feng, GuoYan Wang, YuanYuan Zhu, YiNing Zheng, JunHu Yao, Lei Chen, Lu Deng   +6 more
wiley   +1 more source

Evidence for presence of nonesterified fatty acids as potential gustatory signaling molecules in humans.

Chemical Sensors, 2013
Gustatory fatty acid signaling termed "fatty acid taste" is initiated when nonesterified fatty acids (NEFA) bind to putative fat receptors on taste receptor cells.
B. Kulkarni, R. Mattes
semanticscholar   +1 more source

Effects of obesity‐associated plasma markers on adipose stem cell function and epigenetic regulation

Obesity, EarlyView.
Abstract Objective This study investigates the correlations between obesity‐related plasma markers and epigenetic/inflammatory changes in white adipose tissue (WAT), focusing on adipose‐derived stem cells (ASCs). We hypothesize that obesity modulates histone H3K27 marks, modified by demethylases (lysine‐specific demethylase 6A and 6B [KDM6A/KDM6B]) and
Andressa França Sousa Bispo, Jussara de Jesus Simao, Miguel Ambrizzi Moraes, Ana Beatriz Marques Abel, Victor Tadeu Gonçalves Plata, Monica Marques Telles, André Valente Santana, Paula Volpe, Lucia Maria Armelin‐Correa, Maria Isabel Cardoso Alonso‐Vale   +9 more
wiley   +1 more source