Results 101 to 110 of about 10,782 (215)
Reengineering and Discovery of Nonribosomal Peptide Synthetases
, 2010 Nonribosomal peptides are an important class of natural products including the life-saving antibiotics penicillin and vancomycin and the deadly microcystins and cereulide. This important category of natural products is thus a focus of many research labs
Evans, Bradley S.
core
New Plant Protection, Volume 3, Issue 2, June 2026.We developed a genome‐integrated CRISPR/Cas12a system for Xenorhabdus budapestensis XBD8, which enables precise deletion or replacement of DNA fragments ranging from 379 to 45,168 bp, with a success rate exceeding 90%. Application of this tool for the dynamic regulation of fabclavine‐8 biosynthesis resulted in a 1.90‐fold increase in production ...
Wenfeng Gan +4 more
wiley +1 more source
PLoS ONE, 2017 Aspergillus hancockii sp. nov., classified in Aspergillus subgenus Circumdati section Flavi, was originally isolated from soil in peanut fields near Kumbia, in the South Burnett region of southeast Queensland, Australia, and has since been found ...
John I Pitt +11 more
doaj +1 more source
Kineochelins—A New Group of Siderophores From an Antarctic Bacterium
Microbial Biotechnology, Volume 19, Issue 6, June 2026.Genome‐guided analysis of an Antarctic Actinokineospora strain led to the discovery of kineochelins, a new group of siderophores involved in iron sequestration and microbial competition. Kineochelin production inhibits co‐occurring bacteria and clinically relevant yeasts, highlighting Antarctic microorganisms as promising sources of bioactive natural ...
Stanislava Kralova +12 more
wiley +1 more source
, 2016 Analysis of naphthyridinomycin gene cluster revealed that this antibiotic is generated by nonribosomal peptide synthetase (NRPS) machinery. However, four modules encoded by two genes do not correspond with the structural units in the final product ...
Yue Zhang (30585) +7 more
core +1 more source
Identification and structure of nonribosomal peptide synthetases in Cochliobolus miyabeanus TG12bL2.
, 2016 Identification and structure of nonribosomal peptide synthetases in Cochliobolus miyabeanus TG12bL2.
Juan J. Gutierrez-Gonzalez (131256) +6 more
core +1 more source
New Microbes and New Infections, 2017 We report the draft genome sequence of Haloferax alexandrinus strain Arc-hr (CSUR P798), isolated from the human gut of a 10-year-old Amazonian individual. Its 3 893 626 bp genome exhibits a 66.00% GC content.
S. Khelaifia +3 more
doaj +1 more source
, 2023 Nonribosomal peptide synthetases produce many important peptide natural products and are centred around carrier proteins (CPs) that deliver intermediates to various catalytic domains.
Tailhades, Julien +8 more
core +1 more source
Distinct roles for intra- and extracellular siderophores during Aspergillus fumigatus infection.
PLoS Pathogens, 2007 Siderophore biosynthesis by the highly lethal mould Aspergillus fumigatus is essential for virulence, but non-existent in humans, presenting a rare opportunity to strategize therapeutically against this pathogen.
Markus Schrettl +9 more
doaj +1 more source
Reprogramming Promiscuous Nonribosomal Peptide Synthetases for Production of Specific Peptides
, 2019 Pairs of docking domains (DDs) mediate the selective interations between adjacent nonribosomal peptide synthetases (NRPSs) to form defined protein–protein interactions resulting in defined peptide sequences.
Bode, H. +5 more
core +1 more source