Results 51 to 60 of about 627,327 (211)

Sfp-type PPTase inactivation promotes bacterial biofilm formation and ability to enhance wheat drought tolerance

open access: yesFrontiers in Microbiology, 2015
Paenibacillus polymyxa is a common soil bacterium with broad range of practical applications. An important group of secondary metabolites in P. polymyxa are nonribosomal peptide and polyketide derived metabolites (NRP/PK).
Salme eTimmusk
doaj   +1 more source

Prediction of monomer isomery in Florine: a workflow dedicated to nonribosomal peptide discovery. [PDF]

open access: yesPLoS ONE, 2014
Nonribosomal peptides represent a large variety of natural active compounds produced by microorganisms. Due to their specific biosynthesis pathway through large assembly lines called NonRibosomal Peptide Synthetases (NRPSs), they often display complex ...
Thibault Caradec   +6 more
doaj   +1 more source

Identification of the Biosynthetic Gene Cluster of New Piperazic Acid-Containing Lipopeptides with Cytotoxic Activity in the Genome of Marine Streptomyces PHM034

open access: yesMetabolites, 2023
Three novel lipopeptides, PM130391 (1), PM130392 (2), and PM140293 (3) were obtained from cultures of Streptomyces tuirus PHM034 isolated from a marine sediment.
Ana Ceniceros   +7 more
doaj   +1 more source

Chapter 14 Biosynthesis of Nonribosomal Peptide Precursors

open access: yes, 2009
Nonribosomal peptides are natural products typically of bacterial and fungal origin. These highly complex molecules display a broad spectrum of biological activities, and have been exploited for the development of immunosuppressant, antibiotic ...
Wilkinson, Barrie   +3 more
core   +1 more source

Antibacterial Property of a Coral-Associated Bacterium Pseudoalteromonas luteoviolacea Against Shrimp Pathogenic Vibrio harveyi (In Vitro Study)

open access: yesHayati Journal of Biosciences, 2005
A coral-associated bacterium was successfully screened for secondary metabolites production based on PCR amplification of the nonribosomal peptide synthetase gene and was identified as closely related to Pseudoalteromonas luteoviolacea based on its 16S ...
OCKY KARNA RADJASA   +5 more
doaj   +3 more sources

Semi‐Artificial Photosynthesis Enables Light‐Driven Biomanufacturing in Non‐Photosynthetic Bacteria

open access: yesAdvanced Science, EarlyView.
A non‐invasive strategy exploits endogenous H2S metabolism in B. subtilis to drive in situ CdS biomineralization, enabling tight bio‐abiotic contact without genetic modification. Light harvested by the biomineralized nanoparticles powers NADPH regeneration, elevating 2’‐fucosyllactose and surfactin titres two‐ to three‐fold.
Jie Zheng   +8 more
wiley   +1 more source

Identification and structure of nonribosomal peptide synthetases in Cochliobolus miyabeanus TG12bL2.

open access: yes, 2016
Identification and structure of nonribosomal peptide synthetases in Cochliobolus miyabeanus TG12bL2.
Juan J. Gutierrez-Gonzalez (131256)   +6 more
core   +1 more source

Molecular basis for depsipeptide HDAC inhibitor combinatorial biosynthesis

open access: yesNature Communications
Polyketides and nonribosomal peptides are important natural product classes with wide-ranging medical and agricultural applications. The analogous enzymatic logic employed by bacterial modular polyketide synthases (PKSs) and nonribosomal peptide ...
Munro Passmore   +8 more
doaj   +1 more source

Resistance to nonribosomal peptide antibiotics mediated by d-stereospecific peptidases

open access: yes, 2018
Nonribosomal peptide antibiotics, including polymyxin, vancomycin, and teixobactin, most of which contain d-amino acids, are highly effective against multidrug-resistant bacteria.
Zhong, Zheng   +9 more
core   +1 more source

Structure and Biosynthesis of Mangotoxin Produced by the Plant Pathogen Pseudomonas syringae

open access: yesAngewandte Chemie, Volume 138, Issue 45, 2 November 2026.
The structure of mangotoxin remained elusive for over two decades. Here, mangotoxin was isolated from the native producer, Pseudomonas syringae pv. syringae, and was determined to be an alkyne‐containing dipeptide. Mangotoxin inhibited the growth of multidrug‐resistant human pathogen Klebsiella pneumoniae.
Alexis H. Murray   +4 more
wiley   +2 more sources

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