Results 81 to 90 of about 137,901 (245)

Applying DanGer Shock Eligibility Criteria to a Real‐World Cohort of Cardiogenic Shock Patients

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background The DanGer Shock trial investigated the effects of adding a microaxial flow pump to guideline‐recommended therapy in patients with ST‐elevation myocardial infarction (STEMI)‐related cardiogenic shock (CS), finding a lower all‐cause mortality at 180 days in the intervention group.
Raffaela Miriam Planka, Lukas Herold, Theresa Glantschnig, Gudrun Sommer, Jonathan Pavek, Stefan Hatzl, Nicolas Verheyen, Christoph Strohhofer, Johannes Gollmer, Ewald Kolesnik, Martin Benedikt, Markus Wallner, Andreas Zirlik, Gabor Toth‐Gayor, Dirk von Lewinski   +14 more
wiley   +1 more source

Derivatization of Small Molecules using Deuterated Analog of Reactive Matrix to Facilitate Identification in Mass Spectrometry Imaging

Chemistry–Methods, EarlyView.
The deuterated FMP‐10 analog, FMP‐10‐d3, enhances identification through isotopic labeling, providing structural insights via unique mass shifts. The approach improves the analysis of neurotransmitters and metabolites, facilitating neurochemical mapping and spatial metabolomics, with applications in neurodegenerative disease research. Mass spectrometry
Theodosia Vallianatou, Lorenzo Jacopo Ilic Balestri, Anna Nilsson, Xiaoqun Zhang, Per Svenningsson, Luke R. Odell, Per E. Andrén, Reza Shariatgorji   +7 more
wiley   +1 more source

Effect of ω‐Conotoxin GVIA on Noradrenaline Release from Postganglionic Sympathetic Neurones in Rabbit Aorta [PDF]

, 2000
Ove A. Nedergaard
openalex   +1 more source

Opportunities and Challenges of the Application of Nuclear Magnetic Resonance‐Based Cerebrospinal Fluid Metabolomics for Clinical Research

Chemistry–Methods, EarlyView.
Cerebrospinal fluid (CSF) is an important diagnostic matrix in neurology. This review illustrates the potentials and pitfalls of current CSF analysis by nuclear magnetic resonance. Created with BioRender.com in BioRender. Berezhnoy, G. (2025) https://BioRender.com/x80l903. Web of Science is owned by Clarivate.
Georgy Berezhnoy, Jannik Sprengel, Claire Cannet, Nils Pompe, Christoph Trautwein   +4 more
wiley   +1 more source

Generation of Pseudo Metabolites as a Side Reaction in On‐Tissue Chemical Derivatization in Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry Imaging

Chemistry–Methods, EarlyView.
On‐tissue chemical derivatization reagents enhance sensitivity and specificity, but the impact of side reactions remains understudied. The reactive matrix FMP‐10 promotes Mukaiyama‐like condensation reactions between endogenous metabolites to form pseudo metabolites that are structurally identical to endogenous metabolites.
Tobias Bausbacher, Alessa L. Henneberg, Stephanie Meyer, Stefan Schmidt, Aubry K. Miller, Christiane A. Opitz, Carsten Hopf   +6 more
wiley   +1 more source

Comparative Bioequivalence and Safety Evaluation of Ibuprofen/Phenylephrine Hydrochloride Fixed‐Dose Combination Tablets in Healthy Chinese Volunteers

Clinical Pharmacology in Drug Development, EarlyView.
Abstract This single‐center, randomized, open‐label bioequivalence program compared two fixed‐dose combination (FDC) tablets containing ibuprofen (200 mg) and phenylephrine hydrochloride (10 mg) from different manufacturers in healthy Chinese adults under fasting and fed conditions. A three‐period, partially replicated crossover design was used for the
Menghan Ye, Rui Zhang, Jing Wan, Jinping Zhou, Pengpeng Guo, Dianwen Yu, Peixia Li, Yani Liu, Shaojun Shi   +8 more
wiley   +1 more source

Supplementation with Lactobacillus helveticus NS8 alleviated behavioral, neural, endocrine, and microbiota abnormalities in an endogenous rat model of depression

Frontiers in Immunology
IntroductionMajor depressive disorder is a condition involving microbiota–gut–brain axis dysfunction. Increasing research aims to improve depression through gut microbiota regulation, including interventions such as probiotics, prebiotics, and fecal ...
Husile Alatan, Shan Liang, Shan Liang, Yosuke Shimodaira, Xiaoli Wu, Xu Hu, Tao Wang, Jia Luo, Katsunori Iijima, Feng Jin, Feng Jin   +10 more
doaj   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

RESPONSES OF THE CARDIOVASCULAR SYSTEM OF THE RAT TO NORADRENALINE INFUSIONS AND THEIR MODIFICATION BY ADRENOCEPTOR BLOCKING AGENTS [PDF]

, 1977
F. J. Imms, R Neame, David Powis
openalex   +1 more source

Separable actions of acetylcholine and noradrenaline on neuronal ensemble formation in hippocampal CA3 circuits

, 2021
Luke Y. Prince, Travis Bacon, Rachel Humphries, Krasimira Tsaneva‐Atanasova, Claudia Clopath, Jack R. Mellor   +5 more
openalex   +1 more source