Results 41 to 50 of about 8,701 (163)

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

Preparation and Evaluation of Microbial Resistance of Nortriptyline Mouthwash Based on Pharmaceutical Pharmacopoeia Standards with the Aim of Application in Oral Mucositis [PDF]

Journal of Ardabil University of Medical Sciences
Background: Oral mucositis as a complication of chemotherapy has posed significant challenges to the quality of life in cancer patients. Tricyclic antidepressants, including nortriptyline can control the pain caused by mucositis by inhibiting sodium ...
Taher Sadeghian, Saeideh Allahyari
doaj  

Characterising the Economic Burden of Functional Dyspepsia: A Cost‐of‐Illness Study of Direct and Indirect Costs

United European Gastroenterology Journal, Volume 14, Issue 7, September 2026.
ABSTRACT Background Functional dyspepsia (FD) is a prevalent disorder of gut‐brain interaction (DGBI) and is associated with substantial impact on health care utilisation. However, analyses examining patient‐specific characteristics that contribute to this burden remain limited.
Daan H. C. A. Bosch, Brigitte A. B. Essers, Abraham B. Beckers, Johanna T. W. Snijkers, Bjorn Winkens, Ad A. M. Masclee, Daniel Keszthelyi   +6 more
wiley   +1 more source

Comparative effects of pregabalin and nortriptyline on post-burn neuropathic pain

Journal of Current Biomedical Reports
This clinical trial evaluates the effectiveness of nortriptyline and pregabalin in managing chronic pain in burn patients after discharge. Current treatments like acetaminophen and non-steroidal anti-inflammatory drugs (NSAIDs) are insufficient, leading ...
Cyrus Emir Alavi, Siamak Rimaz, Babak Bakhshayesh Eghbali, Hossein Khoshrang, Mohaya Farzin, Anahita Emir Alavi, Rozheen Mohseni, Roghaye Zare   +7 more
doaj   +1 more source

A Metabolomic Signature Predicts Gout Flare Clinical Outcome Associated With Colchicine Prophylaxis

Arthritis &Rheumatology, Volume 78, Issue 8, Page 1765-1775, August 2026.
Objective This study investigated that serum metabolomics, before urate‐lowering therapy (ULT) initiation, could serve as a biomarker for responsiveness to colchicine prophylaxis in patients with gout commencing treat‐to‐target ULT. Methods We studied a multicenter prospective cohort (n = 409) initiating treat‐to‐target ULT plus colchicine prophylaxis.
Wenyan Sun, Lingfang Xu, Haibing Chen, Mingshu Sun, Zhiqiang Li, Rui Li, Lidan Ma, Hui Zhang, Aichang Ji, Yuwei He, Na Wu, Le Yan, Robert Terkeltaub, Changgui Li   +13 more
wiley   +1 more source

Nortriptyline versus fluoxetine in the treatment of major depressive disorder: a six-month, double-blind clinical trial

Clinical Pharmacology: Advances and Applications, 2012
SN Hashemi1, HR Ghafarian Shirazi2,3, A Mohamadi4, GH Zadeh-Bagheri5, KH Noorian5, M Malekzadeh21Department of Psychiatry, Faculty of Medicine, 2Research Center of Social Factors Affecting Health, Yasuj University of Medical Sciences, Yasuj, 3School of ...
Hashemi SN, Ghafarian Shirazi HR, Mohammadi A, Zadeh-Bagheri GH, Noorian KH, Malekzadeh M   +5 more
doaj  

Relationship Between Sexual Attitude and Sexual Function Among Iranian Women and Men During Pregnancy: A Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Sexual function is considered an essential criterion for enhancing the quality of life, encompassing not only the genital component but also mental and physical factors. The present study was conducted to determine the relationship between sexual attitude and sexual function among Iranian women and men during pregnancy ...
Sepideh Mashayekh‐Amiri, Mobina Ahmadi, Elnaz Hemati, Mojgan Mirghafourvand   +3 more
wiley   +1 more source

Cigarette Smoke‐Exposed Alveolar Epithelial Cell‐Derived Exosomes Exacerbate Skeletal Muscle Dysfunction Through HDAC2 Signalling

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.
ABSTRACT Background Skeletal muscle dysfunction (SMD) is a common extrapulmonary complication of chronic obstructive pulmonary disease (COPD). Histone deacetylase 2 (HDAC2) is closely involved in the suppression of inflammatory transcription and is progressively reduced during COPD progression.
Chao Li, MingZhi Ou, Gang Jiang, GuiXian Zheng, YongLiang Jiang   +4 more
wiley   +1 more source

Dietary Patterns and Food Choices of Adults With Inflammatory Bowel Disease in New Zealand

JGH Open, Volume 10, Issue 8, August 2026.
ABSTRACT Aims This study aimed to assess current dietary patterns in adults with inflammatory bowel disease (IBD) in New Zealand and to evaluate associations with current self‐reported disease activity and well‐being. Methods A prospective online survey was conducted using validated dietary data collection instruments.
Peter Vivian Acire, Angharad Vernon‐Roberts, Andrew S. Day   +2 more
wiley   +1 more source

Study of the effect of nortriptyline and fluvoxamine on psychomotor functions in healthy volunteers

Indian Journal of Psychological Medicine, 2010
Background: Today, many antidepressants are available, but they often cause adverse effects, particularly psychomotor and cognitive. It leads to patient maladjustment and may impair psychomotor performance. Fluvoxamine is a newer antidepressant and hence
Khade Ajay, Bashir Mohammed Shakeel, Kale A, Turankar Avinash   +3 more
doaj