Airway Involvement in Conradi–Hünermann–Happle Syndrome: A Novel Clinical Manifestation
We report the first documented case of airway involvement in Conradi–Hünermann–Happle syndrome (CDPX2), an X‐linked dominant form of chondrodysplasia punctata caused by pathogenic variants in EBP. A 2‐month‐old female with genetically confirmed CDPX2 developed severe subglottic stenosis and persistent respiratory distress requiring CPAP; cross ...
Enrique G. Villarreal +3 more
wiley +1 more source
PEGylated Tween 80-functionalized chitosan-lipidic nano-vesicular hybrids for heightening nose-to-brain delivery and bioavailability of metoclopramide. [PDF]
Al-Zuhairy SAS +5 more
europepmc +1 more source
Current advances in nose to brain drug delivery
Venkatesh Prasad S +2 more
openaire +1 more source
The Mental Health Impact of Retrograde Cricopharyngeus Dysfunction (RCPD) and Its Treatment
This study assessed the prevalence of anxiety and depression within patients with retrograde cricopharyngeus dysfunction (RCPD) while evaluating the impact of cricopharyngeal botulinum toxin injection (CPBTI) on associated symptoms. Using validated surveys for anxiety and depression given at specific time intervals, RCPD patients were found to have a ...
Alexander P. Simko, Andrew G. Tritter
wiley +1 more source
Nose-to-brain delivery of a SOD1-stabilizing small molecule ameliorates pathology in an ALS mouse model. [PDF]
Dhandapani R +9 more
europepmc +1 more source
What Are the Key Anatomical Features for the Success of Nose-to-Brain Delivery? A Study of Powder Deposition in 3D-Printed Nasal Casts. [PDF]
Rigaut C +6 more
europepmc +1 more source
Assessment of Hearing Health Among Adults in Rural Health Clinics
Rural health clinics are a critical healthcare system tasked with improving health in rural communities. This study recruited 403 adults from 10 rural healthcare clinics throughout rural Kentucky, mostly within Appalachia, to screen for hearing loss and evaluate the utilization of diagnostic hearing healthcare and found that 70% of participants ...
Mit A. Patel +4 more
wiley +1 more source
Outcomes in the Management of Pediatric Retrograde Cricopharyngeal Dysfunction
ABSTRACT Objective To review the presentation and treatment outcomes of pediatric patients with retrograde cricopharyngeal dysfunction (RCPD). Methods A retrospective chart review was performed on pediatric patients diagnosed with retrograde cricopharyngeal dysfunction (RCPD) and treated with cricopharyngeal botulinum toxin injection (CPBTI).
Aidan P. Wright +3 more
wiley +1 more source
Nanotechnological Advances for Nose to Brain Delivery of Therapeutics to Improve the Parkinson Therapy. [PDF]
Khatri DK +10 more
europepmc +1 more source
Validation of the TruBlue Light Laser for Laryngeal Somatosensory and Perturbation Testing
This study validates a blue light laser method for assessing laryngeal somatosensory function by measuring perceptual thresholds, reflexive responses, discrimination acuity, and vocal perturbations in healthy adults. Results demonstrate that the method provides precise, reliable stimulation and yields quantifiable sensory and acoustic responses ...
Adrianna C. Shembel +6 more
wiley +1 more source

