Results 111 to 120 of about 47,863 (285)

Wising up to NPYs [PDF]

Science-Business eXchange, 2009
Neuropeptide Y has failed many efforts to target for obesity. New research suggests the peptide hormone could be better suited as a target in atherosclerosis and coronary artery disease. The challenge is to figure out whether it acts in the brain or the vascular system and to target the appropriate receptors.
openaire   +2 more sources

Diet transition to a high-fat diet for 3 weeks reduces brain omega-3-fatty acid levels, alters BDNF signaling and induces anxiety & depression-like behavior in adult rats [PDF]

, 2012
Background: The consumption of diets high in calories and low in nutrient value is becoming increasingly common in modern society, which can lead to metabolic disorders like diabetes and obesity, and potentially to psychiatric disorders.
Fernando Gomez-Pinilla, Sandeep Sharma, Yumei Zhuang   +2 more
core   +1 more source

A structural, spectroscopic and theoretical study of the triphenylphosphine chalcogenide complexes of tungsten carbonyl, [W(XPPh3)(CO)5], X=O, S, Se [PDF]

, 2004
The series [W(XPPh3)(CO)5], X=O, S, Se has been structurally determined by X-ray crystallography and fully characterised spectroscopically to provide data for comparing the bonding of the Ph3PX ligands to the metal.
Cook, Julian B., Nicholson, Brian K., Smith, Derek W.   +2 more
core   +2 more sources

Therapeutic potential of neuropeptide Y (NPY) receptor ligands

EMBO Molecular Medicine, 2010
Neuropeptide Y (NPY) is widely distributed in the human body and contributes to a vast number of physiological processes. Since its discovery, NPY has been implicated in metabolic regulation and, although interest in its role in central mechanisms ...
S. Brothers, C. Wahlestedt
semanticscholar   +1 more source

The role of insulin receptor substrate 2 in hypothalamic and beta cell function [PDF]

, 2005
Insulin receptor substrate 2 (Irs2) plays complex roles in energy homeostasis. We generated mice lacking Irs2 in beta cells and a population of hypothalamic neurons (RIPCreIrs2KO), in all neurons (NesCreIrs2KO), and in proopiomelanocortin neurons ...
Al-Qassab, H, Ashford, MLJ, Barsh, GS, Batterham, RL, Bedford, DC, Bell, JD, Choudhury, AI, Claret, M, Clements, M, Diakonov, I, Heffron, H, Hisadome, K, MacColl, G, Moosajee, V, Selman, C, Simmgen, M, Smith, MA, Speakman, JR, Withers, DJ, Xu, AW   +19 more
core  

Deciphering the skeletal interoceptive circuitry to control bone homeostasis

BMEMat, EarlyView.
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu, Jiusi Guo, Zhen Chen, Fengwei Zhang, Billy Kwok Chong Chow, Zhuofan Chen, Kelvin Wai‐Kwok Yeung, Wei Qiao   +7 more
wiley   +1 more source

Influence of disorder on the ferromagnetism in diluted magnetic semiconductors

, 2001
Influence of disorder on the ferromagnetic phase transition in diluted (III,Mn)V semiconductors is investigated analytically. The regime of small disorder is addressed, and the enhancement of the critical temperature by disorder is found both in the mean
A. L. Chudnovskiy, D. Pfannkuche, F. Matsukura, F. Wegner, H. Ohno, H. Ohno, H. Ohno, J. König, J. König, J. Schliemann, J. Schliemann, L. Schäfer, M. Abolfath, M.P Kennett, R.N. Bhatt, T. Dietl, V.I. Litvinov   +16 more
core   +1 more source

Afferent Neuronal Control of Type-I Gonadotropin Releasing Hormone Neurons in the Human. [PDF]

, 2013
Understanding the regulation of the human menstrual cycle represents an important ultimate challenge of reproductive neuroendocrine research. However, direct translation of information from laboratory animal experiments to the human is often complicated ...
Hrabovszky, Erik, Liposits, Zsolt
core   +1 more source

Synthesis, Characterization, and Electrochemical Properties of Tri‐ and Tetranuclear CoIII‐Oxo Complexes

European Journal of Inorganic Chemistry, EarlyView.
A series of three tetranuclear and two trinuclear Co(III) carboxylate complexes are synthesized and thoroughly spectroscopically and electrochemically characterized. The relative stability of the tetranuclear versus trinuclear complexes is investigated by density functional theory calculations, and the infrared and ultraviolet/visible spectra are ...
Timo Fockenberg, Niklas Sülzner, Hatem M. A. Amin, Christoph Wölper, Christof Hättig, Stephan Schulz   +5 more
wiley   +1 more source

Unveiling Solvent‐Dependent Divergent Hydrogen Production Pathways during the Dehydrogenation of Formic Acid Using N,N′‐Iminopyridine Ruthenium(II) Complexes

European Journal of Inorganic Chemistry, EarlyView.
A readily available, efficient RuII catalyst mediates hydrogen production via formic acid dehydrogenation, via distinct, solvent‐dependent hydrogen production pathways. In water, catalyst robustness is observed, generating turnover numbers (TONs) of 13 791 under stepwise addition, while displaying sustained activity under continuous addition conditions
Thabiso Mphuti, Rotondwa Mphephu, Moegamat Joseph, Andrew J. Swarts   +3 more
wiley   +1 more source