Results 191 to 200 of about 69,773 (297)

Work Disability, Early Retirement, and Loss of a Loved One in the World Trade Center Health Registry Cohort

American Journal of Industrial Medicine, Volume 69, Issue 5, Page 382-395, May 2026.
ABSTRACT Background Existing research on the economic outcomes of 9/11 remains limited and has primarily focused on early retirement. Little is known about the prevalence of work disability and loss of a loved one and whether they are associated with survey attrition.
Jennifer Brite, Matthew Di Vitto, Janna Metzler   +2 more
wiley   +1 more source

Dissecting the MAPK signaling landscape in malignant melanoma: from BRAF and NRAS mutations to precision combination therapies. [PDF]

Front Cell Dev Biol
Fang X, Wang S, Fu S.
europepmc   +1 more source

Noonan Syndrome Spectrum Disorders Predispose to Systemic Lupus Erythematosus: Case Report and Critical Review of the Literature

American Journal of Medical Genetics Part A, Volume 200, Issue 5, Page 1091-1097, May 2026.
ABSTRACT RASopathies are clinically overlapping neurodevelopmental syndromes resulting from germline mutations in genes involved in the rat sarcoma/mitogen‐activated protein kinases (RAS/MAPK) pathway. Historically, RASopathies have been described by clinical phenotypes, such as Noonan syndrome and Neurofibromatosis type I.
Anastasia‐Vasiliki Madenidou, Gillian I. Rice, James O'Sullivan, Ben Parker, Ian N. Bruce, Emma Burkitt‐Wright, Tracy A. Briggs   +6 more
wiley   +1 more source

Molecular Profiling and Tumor Biomarker Analysis of GOG281/LOGS: A Positive Late-Phase Trial of Trametinib for Recurrent/Persistent Low-Grade Serous Ovarian Carcinoma. [PDF]

Clin Cancer Res
Hollis RL, Miller A, Lankes HA, Wong KK, Rodgers W, Millan D, Carty K, Coleman RL, Moore KN, Alvarez Secord A, O'Malley DM, Chan JK, Hagemann AR, Gaillard S, Guntupalli SR, Edelson MI, Rose PG, Dorigo O, Banerjee S, Ewing A, Churchman M, Sood AK, Herrington CS, Gourley C, Gershenson DM.   +24 more
europepmc   +1 more source

TYRO3, AXL, MERTK and Their Ligands in Brain Metastases From Colorectal Cancers

Cancer Medicine, Volume 15, Issue 5, May 2026.
TYRO3, AXL, and MERTK are expressed in primary tumors and extra‐cerebral and brain metastases from colorectal cancers. AXL, primarily expressed in endothelial cells, is the more conserved marker between primary tumor and brain metastasis. The Low AXL/High GAS6 ratio is of poor prognosis in metastatic colorectal cancer patients.
Anaïs Noblanc, Fatima Dkhissi, Pierre‐Olivier Guichet, Lucie Lebeau, Serge Milin, Sheik Emambux, Pauline Roussille, Camille Evrard, Lucie Karayan‐Tapon, David Tougeron, Omar Benzakour, Violaine Randrian   +11 more
wiley   +1 more source

PHI-501, a dual inhibitor of RAF and DDR1/2, overcomes MAPK drug resistance in Melanoma. [PDF]

Cancer Cell Int
Kim SM, Cho S, Sung GJ, Nam KY, Yoon J, Sim T, Ahn JB, Shin SJ.   +7 more
europepmc   +1 more source

NRAS NP_002515.1:p.G12X [PDF]

, 2020
openaire   +1 more source

GATA2 Mutations Predict Poor Prognosis in Transplanted Myeloid Neoplasms

Cancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Background GATA binding protein 2 (GATA2) plays a crucial role in the differentiation, proliferation, and maintenance of hematopoietic stem cells (HSCs). GATA2 mutations have been identified in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS), but the impact of somatic GATA2 mutations on prognosis remains controversial ...
Xian Zhang, Bingjie Wang, Yujun Dong, Qingya Wang, Qian Wang, Jialin Zhu, Qingyun Wang, Na Han, Yuan Li   +8 more
wiley   +1 more source

MEK Inhibition Reduces Vascular Malformations and Gene Dysregulation in NRAS^Q61R Human Endothelial Cells. [PDF]

Pediatr Blood Cancer
Alharbi S, Wagner A, Merkle S, Pastura P, McDaniel CG, Fox D, Xu Y, Le Cras TD.   +7 more
europepmc   +1 more source

NRAS wt Allele [PDF]

, 2020
openaire   +1 more source